The Population Council’s Center for Biomedical Research (CBR) is a vibrant hub of scientific investigation and product development. Our scientists address critical questions in reproductive health and develop innovative products that protect the health and well-being of millions of people worldwide.

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Submissions from 2025

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Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development, Barbara Friedland, Holly Gundacker, Sharon Achilles, Beatrice A. Chen, Craig Hoesley, Barbra A. Richardson, Clifton W. Kelly, Jeanna Piper, Sherri Johnson, Brid Devlin, John Steytler, Kyle Kleinbeck, Bindi Dangi, Chantel Friend, Mei Song, Barbara Mensch, Ariane van der Straten, Cindy Jacobson, Craig W. Hendrix, Jill Brown, Diana Blithe, Sharon L. Hiller, and on behalf of the MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network

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Consensus recommendations for measuring the impact of contraception on the menstrual cycle in contraceptive clinical trials, Amelia C.L. Mackenzie, Stephanie Chung, Emily Hoppes, Nora Miller, Anne E. Burke, Sharon Achilles, C. Leigh Allen, Luis Bahamondes, Diana Blithe, et al., Lisa Haddad, and Regine Sitruk-Ware

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Development of a transdermal gel for reversible male contraception, Régine Sitruk-Ware, Diana Blithe, Stephanie T. Page, and Christina Wang

Submissions from 2024

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Acceptability and feasibility study for the DVR in three cities in Indonesia (Bali, Makassar and Tegal), ThinkPlace and UNAIDS

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A drug-drug interaction study to evaluate the effects of strong CYP3A induction and inhibition on the pharmacokinetics of Segesterone Acetate and Ethinyl Estradiol from the Annovera® contraceptive vaginal system, Marlena Gehret Plagianos, Narender Kumar, and Harvey Kushner

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A new vision for male contraception research and development, Régine Sitruk-Ware, James Sailer, David Serfaty, and Richard A. Anderson

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A Randomized, Phase 1, Open-Label Study in Healthy HIV-Negative Women to Evaluate the Pharmacokinetics, Safety and Bleeding Patterns Associated with 90-Day Use of Matrix Vaginal Rings Containing 200 mg Dapivirine and 320 mg, Barbara Friedland and Holly Gundacker

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Assessing the acceptability of, adherence to and preference for a dual prevention pill (DPP) for HIV and pregnancy prevention compared to oral pre-exposure prophylaxis (PrEP) and oral contraception taken separately: Protocols for two randomised, controlled, cross-over studies in South Africa and Zimbabwe, Barbara Friedland, Nyaradzo M. Mgodi, Thesla Palanee-Phillips, Sanyukta Mathur, Marlena Gehret Plagianos, Irene Bruce, Maud Lansiaux, Caroline Murombedzi, Petina Musara, Adlight Dandadzi, Krishnaveni Reddy, Nkosiphile Ndlovu, Sihle K. Zulu, Lerato R. Shale, Brady Zieman, and Lisa Haddad

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Biomimetic ghost nanomedicine-based optotheranostics for cancer, Rajendra Prasad, Vaskuri G.S. Jyothi, Nagavendra Kommineni, Ravi Teja Bulusu, Barbara B. Mendes, Jonathan F. Lovell, and João Conde

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Borophene: An emerging nanomaterial for biomedical applications, Sagar Salave, Nimeet Desai, Siddharth Salve, Dhwani Rana, Shreya Pande, Pranav Patel, Shubhangi Khode, Derajram Benival, and Nagavendra Kommineni

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Center for Biomedical Research at the Population Council, Population Council

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Correcting the scientific record on abortion and mental health outcomes, Julia H. Littell, Kathryn M. Abel, M. Antonia Biggs, Robert W. Blum, Diana Greene Foster, Lisa Haddad, Brenda Major, Trine Munk-Olsen, Chelsea Polis, Gail Erlick Robinson, Corinne H. Rocca, Nancy Felipe Russo, Julia Steinberg, Donna E. Stewart, Nada Logan Stotland, Ushma D. Upadhyay, and Jenneke van Ditzhuijzen

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Correlates of adherence to oral and vaginal pre-exposure prophylaxis (PrEP) among adolescent girls and young women (AGYW) participating in the MTN-034/REACH Trial, Kenneth Ngure, Erica N. Browne, Krishnaveni Reddy, Barbara Friedland, Ariane van der Straten, Thesla Palanee-Phillips, Rita Nakalega, Brenda Gati, Hadijah N. Kalule, Bekezela Siziba, Lydia Soto-Torres, Gonasagrie Nair, Morgan Garcia, Connie Celum, and Sarah T. Roberts

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Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy, Satish Rojekar, Amol D. Gholap, Namdev Togre, Priyanka Bhoj, Clement M. Haeck, Navnath Hatvate, Nidhi Singh, Jyotsna Vitore, Sagar Dhoble, Snehal Kashid, and Vandana Patravale

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Development of generic liposome products for drug delivery, Sagar Salave, Dhwani Rana, Pranav Patel, Raghav Gupta, Derajram Benival, and Nagavendra Kommineni

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Differential expression of HIV target cells CCR5 and a4b7 in tissue resident memory CD4 T cells in endocervix during the menstrual cycle of HIV seronegative women, Sakthivel Govindaraj, Tyree Staple, Gina Bailey Herring, Sadia J. Rahman, Hemalatha Babu, Chris Ibegbu, Marisa R. Young, C. Christina Mehta, Lisa Haddad, Alicia K. Smith, and Vijayakumar Velu

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Editorial: Multipurpose prevention technologies for HIV, STIs and pregnancies, Barbara Friedland, Andrea Ries Thurman, Harriet Nuwagaba-Biribonwoha, and R. Karl Malcolm

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Expert opinion on the use of contraception in people with multiple sclerosis, Jan Hillert, Riley Bove, Lisa Haddad, Kerstin Hellwig, Maria Houtchens, Melinda Magyari, Gabriele S. Merki-Feld, Scott Montgomery, Rossella E. Nappi, Egon Stenager, Heidi Thompson, Zeliha Tulek, Elisabetta Verdun Di Cantogno, and Manuela Simoni

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Ex vivo colonic tissue susceptibility to HIV-1 in cisgender men and women, Patrick Barnable, Sampurna Mukhopadhyay, Larisa Kizima, Narender Kumar, Marlena Gehret Plagianos, Saurabh Mehandru, and Natalia Teleshova

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Family planning and contraception in people with multiple sclerosis: Perspectives for obstetricians, gynaecologists, and other health care professionals involved in reproductive planning, Gabriele S. Merki-Feld, Riley Bove, Lisa Haddad, Kerstin Hellwig, Jan Hillert, Maria Houtchens, Melinda Magyari, Scott Montgomery, Manuela Simoni, Egon Stenager, Heidi Thompson, Zeliha Tulek, Kurt Marhardt, and Rossella E. Nappi

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Genome editing and its role in vaccine, diagnosis, and therapeutic advancement, Deepanker Bisht, Sagar Salave, Nimeet Desai, Purnima Gogoi, Dhwani Rana, Prachurya Biswal, Gautami Sarma, Derajram Benival, Nagavendra Kommineni, and Dhruv Desai

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Health Outcomes around Pregnancy and Exposure to HIV/Antiretrovirals (HOPE) study protocol: A prospective observational cohort study of reproductive-aged women living with HIV, Deborah Kacanek, Lynn M. Yee, Tzy Jyun Yao, Jessica Lee, Ellen G. Chadwick, Paige L. Williams, Emily A. Barr, Claire A. Berman, Mariam Davtyan, Alex Diperna, Amanda Flores, Jennifer Green, Lisa Haddad, and et al.

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In situ photo responsive biodegradable nanoparticle forming intrauterine implant for drug delivery to treat ovarian diseases: A rationale-based review, Leander Corrie, Nagavendra Kommineni, Jaskiran Kaur, Ankit Awasthi, Raghunandan Gundaram, and Latha Kukati

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“Killing two birds with one stone” – a qualitative study on women’s perspectives on the dual prevention pill in Johannesburg, South Africa, Siyanda Tenza, Lydia Mampuru, Mpho Moji, Sihle K. Zulu, Lorna Begg, Irene Bruce, Krishnaveni Reddy, Barbara Friedland, Thesla Palanee-Phillips, and Sanyukta Mathur

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Knowledge of abortion legality among health facility staff in Ghana, Grace Sheehy, Chelsea Polis, Easmon Otupiri, and Caroline Moreau

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Matching Design to Desire: Developing the Next Generation of Contraceptives, Lorna Begg and Sanyukta Mathur

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Metabolism of progestogens used for contraception and menopausal hormone therapy, Frank Z. Stanczyk, Alexandra McGough, Laura Chagam, and Régine Sitruk-Ware

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Microneedle of drug delivery systems, Fouad Damiri, Hitendra M. Patel, Sagar Salave, Nagavendra Kommineni, B.H. Jaswanth Gowda, Karthika Paul, Sanju Bala Dhull, and Mohammed Berrada

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Mifepristone as a non-emergency contraceptive among women of reproductive age: A protocol for systematic review and meta-analysis, Miriam Nkangu, Caroline Frisendahl, Chelsea Polis, Tracy Chen, Evan Sterling, Rebecca Gomperts, Marlena Gehret Plagianos, Lisa Haddad, and Kristina Gemzell-Danielsson

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MTN-030/IPM-041: A Phase 1, Randomized, Double-Blind Pharmacokinetic and Safety Study of Dapivirine/Levonorgestrel Vaginal Rings, Barbara Friedland and Holly Gundacker

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Nanofibrous microspheres: A biomimetic platform for bone tissue regeneration, Nimeet Desai, Shreya Pande, Lalitkumar K. Vora, and Nagavendra Kommineni

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Nestorone (segesterone acetate) effects on neuroregeneration, Regine Sitruk-Ware, Heather Sussman, Roberta Brinton, Michael Schumacher, Patrick Singer, Narender Kumar, Alejandro F. De Nicola, Martine El-Etr, Rachida Guennoun, and Cesario V. Borlongan

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Peptide conjugated boron neutron capture therapy for enhanced tumor targeting, Vaskuri G.S.Sainaga Jyothi and Nagavendra Kommineni

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Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings, Sharon Achilles, Clifton W. Kelly, Craig Hoesley, Diana Blithe, Jill Brown, Barbra A. Richardson, Brid Devlin, Craig W. Hendrix, Samuel M. Poloyac, Mark A. Marzinke, Holly Gundacker, Devika Singh, Jeanna Piper, Sherri Johnson, John Steytler, Beatrice A. Chen, and on behalf of the MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network

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Phase I dose volume escalation of rectally administered PC-1005 to assess safety, pharmacokinetics, and antiviral pharmacodynamics as a multipurpose prevention technology (MTN-037), Ken Ho, Craig Hoesley, Peter L. Anderson, José Fernández-Romero, Barbara Friedland, Natalia Teleshova, Patrick Barnable, et al., and MTN-037 Study Team

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Regulatory challenges of new male contraceptive methods, Regine Sitruk-Ware, Lisa Soule, Jonathan P. Jarow, and Viveca Odlind

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Risk factors for and outcomes of ring expulsions with a one year contraceptive vaginal system, Marlena Gehret Plagianos, Shaalini Ramanadhan, Ruth Merkatz, Vivian Brache, Barbara Friedland, and Lisa Haddad

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Special Issue “Latest Advances in Nanomedicine Strategies for Different Diseases”, Nagavendra Kommineni and Veera Ganesh Yerra

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Substance use during pregnancy and postpartum among individuals with perinatally-acquired HIV in the United States, Lynn M. Yee, Kathleen M. Powis, Jennifer Jao, Lisa Haddad, Tzy-Jyun Yao, Emily Barr, Suzanne Siminski, Carly Broadwell, Ellen G. Chadwick, and Deborah Kacanek

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The implementation and impact of a 3-week postpartum telephone visit, Julia Grande, Talitha L. Bruney, Vruti Virani, and Marlena Gehret Plagianos

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The Population Council’s Center for Biomedical Research Implements an End-to-End Approach to Product Development, Anita Bhatia Garg, Lisa Haddad, Sanyukta Mathur, and Lorna Begg

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The PrEP Ring Quarterly—Edition 1, October 2024, IPM South Africa

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The Promise of Vaginal Rings: From the Global Leader in Vaginal Ring Development and Implementation, Population Council

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The role of advocacy in sustaining male contraceptive research and development, Heather L. Vahdat, Logan M. Nickels, Kevin Shane, David Serfaty, and Régine Sitruk-Ware

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Use of at-home sperm concentration testing in a male hormonal contraceptive efficacy clinical trial, Christina Wang, Yanhe Lue, Ronald S. Swerdloff, Dayton Morris, Youngju Pak, Brian T. Nguyen, Peter Y. Liu, Mitchell Creinin, Prasanth Surampudi, David K. Turok, Kenneth I. Aston, Richard A. Anderson, John Reynolds-Wright, Stephanie T. Page, John K. Amory, Clint Dart, Jeffrey M. Kroopnick, Min S. Lee, Régine Sitruk-Ware, and Diana Blithe

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Vaginal progesterone to prevent spontaneous preterm birth in women with a sonographic short cervix: The story of the PREGNANT trial, Roberto Romero, Arun Meyyazhagan, Sonia S. Hassan, George W. Creasy, and Agustin Conde-Agudelo

Submissions from 2023

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Adherence, safety, and choice of the monthly dapivirine vaginal ring or oral emtricitabine plus tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis among African adolescent girls and young women: A randomised, open-label, crossover trial, Gonasagrie Nair, Connie Celum, Daniel Szydlo, Elizabeth R. Brown, Carolyne Akello, Rita Nakalega, et al., and John Steytler

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Baseline preferences for oral pre-exposure prophylaxis (PrEP) or dapivirine intravaginal ring for HIV prevention among adolescent girls and young women in South Africa, Uganda and Zimbabwe (MTN-034/IPM-045 study), Kenneth Ngure, Barbara Friedland, Daniel W. Szydlo, Sarah Roberts, Morgan Garcia, Lisa Levy, Carolyne Akello, Krishnaveni Reddy, Thesla Palanee-Phillips, Pippa Macdonald, Bekezela Siziba, Lydia Soto-Torres, Sybil Hosek, Sharon L. Hillier, Gonasagrie Nair, Connie Celum, and Ariane van der Straten

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Characterization of viruses in Phase 3 and Phase 3b trials (the Ring Study and the Dapivirine Ring Extended Access and Monitoring Trial) of the Dapivirine vaginal ring for human immunodeficiency virus type 1 infection risk reduction, John Steytler, Charles Craig, Elna van der Ryst, Ben Van Baelen, Jeremy Nuttall, Neliette van Niekerk, John Mellors, Urvi Parikh, and Carole Wallis

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Clinical presentation, treatment response, and virology outcomes of women who seroconverted in the Dapivirine Vaginal Ring Trials—The Ring Study and DREAM, John Steytler, Elna van der Ryst, Charles Craig, Ben Van Baelen, Jeremy Nuttall, Neliette van Niekerk, John Mellors, Urvi Parikh, and Carole Wallis

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Coming Full Circle: Microbicide Development at the Population Council, James Sailer, Barbara Friedland, Diantha Pillay, Christopher J. Elias, Sharon L. Hillier, and Georgina Caswell

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Commentary: Multipurpose prevention technologies—What about sexually transmitted infections?, Anjanique Mariquit Rosete Lu and Lisa Haddad

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Deep eutectic solvents for subcutaneous delivery of protein therapeutics, Alexander M. Curreri, Jayoung Kim, Michael Dunne, Pavimol Angsantikul, Morgan Goetz, Yongsheng Gao, and Samir Mitragotri

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Design of an international male contraceptive efficacy trial using a self-administered daily transdermal gel containing testosterone and segesterone acetate (Nestorone), John K. Amory, Diana Blithe, Régine Sitruk-Ware, Ronald S. Swerdloff, William J. Bremner, Clint Dart, Peter Y. Liu, Arthi Thirumalai, Brian T. Nguyen, Bradley D. Anawalt, Min S. Lee, Stephanie T. Page, and Christina Wang

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Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration, Satish Rojekar, Anusha R. Pallapati, Judit Gimenez-Roig, Funda Korkmaz, Farhath Sultana, Damini Sant, Clement M. Haeck, Anne Macdonald, Se Min Kim, Clifford J. Rosen, Orly Barak, Marcia Meseck, John Caminis, Daria Lizneva, Tony Yuen, and Mone Zaidi

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Development of mucoadhesive electrospun scaffolds for intravaginal delivery of Lactobacilli spp., a tenside, and metronidazole for the management of bacterial vaginosis, Margaret O. Ilomuanya, Peace O. Bassey, Deborah A. Ogundemuren, Uloma N. Ubani-Ukoma, Alkiviadis Tsamis, Yuwei Fan, Konstantinos Michalakis, Pavimol Angsantikul, Abdulrahman Usman, and Andrew N. Amenaghawon

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Does size matter? A randomized controlled trial to assess the impact of external diameter on adherence to 3 different intravaginal rings among 24 US couples, Irene Bruce, Marlena Gehret Plagianos, Jessica M. Sales, Jessica Atrio, Shakti Shetty, Caio Sant’Anna Marinho, Brady Zieman, Lisa Haddad, and Barbara Friedland

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Drug reprofiling to identify potential HIV-1 protease inhibitors, Sunday Okafor, Abigail Meyer, Jay Gadsden, Fadi Ahmed, Lilian Guzmán, Hashim Ahmed, José Fernández-Romero, and Pavimol Angsantikul

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Equipping providers to offer novel MPTs: Developing counseling messages for the Dual Prevention Pill in clinical studies and beyond, Kate Segal, Danielle M. Harris, Andy Carmone, Lisa Haddad, Sanjay Hadigal, Karin Hatzold, Chris Jones, Eva Lathrop, Jennifer Mason, and Meridith Mikulich

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Evaluating the association of antiretroviral therapy and immune status with hypertensive disorders of pregnancy among people with HIV, Lynn M. Yee, Denise L. Jacobson, Lisa Haddad, Jennifer Jao, Kathleen M. Powis, Deborah Kacanek, Rebecca Zash, Alexandria Diperna, and Ellen G. Chadwick

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Exploring user and stakeholder perspectives from South Africa and Uganda to refine microarray patch development for HIV PrEP delivery and as a multipurpose prevention technology, Ayesha Ismail, Sarah Magni, Anne Katahoire, Florence Ayebare, Godfrey Siu, Fred Semitala, Peter Kyambadde, Barbara Friedland, Courtney Jarrahian, and Maggie Kilbourne-Brook

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Gestational weight gain in persons with HIV in the United States, Jennifer Jao, Deborah Kacanek, Carly Broadwell, Denise L. Jacobson, Ellen G. Chadwick, Paige L. Williams, Kathleen Powis, Lisa Haddad, and Lynn Yee

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Herpes simplex virus type 2 prevalence and association with inflammatory cytokines among sexual and gender minorities living with and without HIV-1 from Lagos, Nigeria, Meropi Aravantinou, Marlena Gehret Plagianos, Afoke Kokogho, Sylvia Adebajo, Rebecca G. Nowak, Elizabeth Shoyemi, Charles Ekeh, Kara Lombardi, Sheila Peel, Stefan Baral, Trevor A. Crowell, Nina Derby, Natalia Teleshova, and Elena Martinelli

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Influence of hormonal contraceptive use and HIV on cervicovaginal cytokines and microbiota in Malawi, Lisa Haddad, Jennifer H. Tang, Nicole L. Davis, Athena P. Kourtis, Lameck Chinula, Albans Msika, Gerald Tegha, Mina C. Hosseinipour, Julie A.E. Nelson, Marcia M. Hobbs, Pawel Gajer, Jacques Ravel, and Kristina De Paris

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New approaches for developing biomarkers of hormonal contraceptive use, Rakhee Sachdeva, Narender Kumar, Vivian Brache, Barbara Friedland, Marlena Gehret Plagianos, Shimin Zhang, Larisa Kizima, Leila Cochon, Ana Sofía Tejada Tabar, Ann K. Blanc, and Ruth Merkatz

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Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a Phase 1 clinical trial: Learning from users to improve acceptability, Mary Kate Shapley-Quinn, Mei Song, Beatrice A. Chen, Brid Devlin, Ellen Luecke, Jill Brown, Diana Blithe, Sharon Achilles, and Ariane van der Straten

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Patent: Combination therapy intravaginal rings, Brid Devlin, Jonathon Holt, Andrew Brimer, Jeremy Nuttall, Karl Malcolm, Susan Fetherston, and Peter Boyd

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Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines, Christina Wang, M. Cristina Meriggiola, John K. Amory, Christopher L.R. Barratt, Hermann M. Behre, William J. Bremner, Alberto Ferlin, Stanton Honig, Zsolt Kopa, Kirk C. Lo, Eberhard Nieschlag, Stephanie T. Page, Jay Sandlow, Régine Sitruk-Ware, Ronald S. Swerdloff, Frederick C.W. Wu, and Dimitrios G. Goulis

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Unique profile of inflammation and immune activation in pregnant people with HIV in the United States, Stephanie Shiau, Denise L. Jacobson, Yanling Huo, Deborah Kacanek, Lynn M. Yee, David B. Williams, Lisa Haddad, Lena Serghides, Kathleen M. Powis, Rhoda Sperling, Paige L. Williams, Jennifer Jao, and Pediatric HIV/AIDS Cohort Study (PHACS)

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Vaginal microbiome, antiretroviral concentrations, and HIV genital shedding in the setting of hormonal contraception initiation in Malawi, Alyssa M. Lantz, Mackenzie L. Cottrell, Amanda H. Corbett, Lameck Chinula, Athena P. Kourtis, Julie A.E. Nelson, Gerald Tegha, Stacey Hurst, Pawel Gajer, Jacques Ravel, Lisa Haddad, Jennifer H. Tang, and Melanie R. Nicol

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Women want choices: Opinions from the Share.Learn.Shape global internet survey about multipurpose prevention technology (MPT) products in development, Barbara Friedland, Marlena Gehret Plagianos, Craig Savel, Virginia Kallianes, C. Martinez, Lorna Begg, K.M. Guthrie, D. Venkatasetty, J. Pickett, and Lisa Haddad

Submissions from 2022

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Acceptability and preference for 3-month versus 1-month vaginal rings for HIV-1 risk reduction among participants in a Phase 1 trial, Sarah Roberts, Imogen Hawley, Ellen Luecke, Barbara Mensch, Theresa Wagner, Craig Hoesley, Tara McClure, Clara P. Dominguez Islas, Jeanna Piper, Albert Y. Liu, and Ariane van der Straten

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Acceptability of PC-1005 gel administered rectally to HIV-1 seronegative adults at three different volume levels (MTN-037), José A. Bauermeister, Ryan C. Tingler, Ken Ho, Rachel Scheckter, Tara McClure, Jontraye Davis, Jeanna Piper, Barbara Friedland, Stacey Edick, Mei Song, Yuqing Jiao, Craig W. Hendrix, and Craig Hoesley

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A content analysis of Reddit users’ posts about challenges to contraceptive care-seeking during COVID-19-related restrictions in the United States, Zoe H. Pleasure, Lori F. Frohwirth, Naomi Li, and Chelsea Polis

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A mixed-methods study of factors influencing postpartum intrauterine device uptake after family planning counseling among women in Kigali, Rwanda, Mariama S. Tounkara, Rosine Ingabire, Dawn L. Comeau, Etienne Karita, Susan Allen, Julien Nyombayire, Rachel Parker, Lisa Haddad, Vanessa Da Costa, Amanda Tichacek, Amelia Mazzei, Jeannine Mukamuyango, and Kristin M. Wall

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Antiviral activity of aframomum melegueta against severe acute respiratory syndrome coronaviruses type 1 and 2, Oneil Mahoney, Claudia Melo, Anthony Lockhart, Nadjet Cornejal, Sahar Alsaidi, Qingli Wu, Jim Simon, Rodolfo Juliani, Thomas Zydowsky, Christine Priano, Adolfina Koroch, and José Fernández-Romero

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Biomimetic targeted theranostic nanoparticles for breast cancer treatment, Suphalak Khamruang Marshall, Pavimol Angsantikul, Zhiqing Pang, Norased Nasongkla, Rusnah Syahila Duali Hussen, and Soracha Dechaumpahi Thamphiwatana

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Bone, Brain, Heart study protocol: A resilient nested, tripartite prospective cohort study of the role of estrogen depletion on HIV pathology, C. Christina Mehta, Kimberly S. Hagen, Anna A. Rubtsova, Cecile D. Lahiri, Vasiliki Michopoulos, Caitlin A. Moran, Lisa Haddad, Kehmia Titanji, Lauren F. Collins, Arshed A. Quyyumi, Gretchen Neigh, Leslee J. Shaw, M. Neale Weitzmann, Lance Waller, and Ighovwerha Ofotokun

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Contraceptive drug, Nestorone, enhances stem cell-mediated remodeling of the stroke brain by dampening inflammation and rescuing mitochondria, Jea-Young Lee, Vanessa Castelli, Narender Kumar, Régine Sitruk-Ware, and Cesario V. Borlongan

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Discovery of novel HIV protease inhibitors using modern computational techniques, Sunday Okafor and Pavimol Angsantikul

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Discovery of novel HIV protease inhibitors using modern computational techniques, Sunday Okafor, Pavimol Angsantikul, and Hashim Ahmed

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Drug repurposing for HIV-1 protease inhibitors: High throughput virtual screening, rigid molecular docking and molecular dynamics studies, Sunday Okafor, Pavimol Angsantikul, and Hashim Ahmed

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Essential oils block cellular entry of SARS-CoV-2 delta variant, Luiz Torres Neto, Maria Lúcia Guerra Monteiro, José Fernández-Romero, Natalia Teleshova, James Sailer, and Carlos Adam Conte Junior

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Estradiol inhibits HIV-1BaL infection and induces CFL1 expression in peripheral blood mononuclear cells and endocervical mucosa, Neeharika Verma, Sampurna Mukhopadhyay, Patrick Barnable, Marlena Gehret Plagianos, and Natalia Teleshova

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Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): A prospective cohort study protocol, Lisa Haddad, Gina Bailey Herring, C. Christina Mehta, Tyree Staple, Marisa R. Young, Sakthivel Govindaraj, Vijayakumar Velu, and Alicia K. Smith

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Exposed and sequestered antigens in testes and their protection by regulatory T cell-dependent systemic tolerance, Jessica Harakal, Hui Qiao, Karen Wheeler, Claudia Rival, Alberta G.A. Paul, Daniel M. Hardy, C. Yan Cheng, Erwin Goldberg, and Kenneth S.K. Tung

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Freeze-drying for the preservation of immunoengineering products, Nagavendra Kommineni, Arun Butreddy, Vaskuri G.S. Sainaga Jyothi, and Pavimol Angsantikul

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High throughput scRNA-Seq provides insights into leydig cell senescence induced by experimental autoimmune orchitis: A prominent role of interstitial fibrosis and complement activation, Yinchuan Li, Panpan Mi, Jiabao Wu, Yunge Tang, Xiaohua Liu, Jinmei Cheng, Yingying Huang, Weibing Qin, C. Yan Cheng, and Fei Sun

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Implementation and evaluation of a large-scale postpartum family planning program in Rwanda: Study protocol for a clinic-randomized controlled trial, Kristin M. Wall, Rosine Ingabire, Amelia Mazzei, Claudine Umuhoza, Rachel Parker, Amanda Tichacek, Azhar Nizam, Jessica M. Sales, Lisa Haddad, Phaedra Corso, Susan Allen, Julien Nyombayire, and Etienne Karita

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Incidence and characteristics of stillbirths before and during the Coronavirus 2019 pandemic, Kavita Vani, Fatima Estrada Trejo, Marlena Gehret Plagianos, Morit Segui, Thammatat Vorawandthanachai, Lisa Nathan, and Francine Hughes

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In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel, Diarmaid J. Murphy, Yahya H. Dallal Bashi, Clare F. McCoy, Peter Boyd, Leeanne Brown, François Martin, Nicole McMullen, Kyle Kleinbeck, Bindi Dangi, Patrick Spence, Bashir Hansraj, Brid Devlin, and R. Karl Malcolm

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MARK2 and MARK4 regulate Sertoli cell BTB dynamics through microtubule and actin cytoskeletons, Elizabeth I. Tang and C. Yan Cheng

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Measuring potential interest in a postpartum contraceptive vaginal ring among breastfeeding women in India, Lorna Begg, James Sailer, Avishek Hazra, Malabika Roy, Ruth Merkatz, Lisa Haddad, Rebecca Brodsky, and John Bongaarts

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mTORC1/rpS6 and p-FAK-Y407 signaling regulate spermatogenesis: Insights from studies of the adjudin pharmaceutical/toxicant model, Lingling Wang, Linxi Li, Xiaolong Wu, Chris K.C. Wong, Adolfo Perrotta, Bruno Silvestrini, Fei Sun, and C. Yan Cheng

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Nestorone nanosuspension-loaded dissolving microneedles array patch: A promising novel approach for “on-demand” hormonal female-controlled peritcoital contraception, Ebru Altuntaş, Ismaiel A. Tekko, Lalitkumar K. Vora, Narender Kumar, Rebecca Brodsky, Olivier Chevallier, Emma McAlister, Qonita Kurnia Anjani, Helen O. McCarthy, and Ryan F. Donnelly

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Patent: System for providing birth control, Bruce Variano

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Progress in male contraception: A brief summary of the Third International Congress on Male Contraception, May 2022, Christina Wang, Diana Blithe, Stephanie Page, David Serfaty, and Régine Sitruk-Ware

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Recap of the Sixth International Symposium on Intrauterine Devices and Systems for Women's Health, Rachel Ferat, Lisa Haddad, Carolyn Westhoff, and David Hubacher

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Results of a phase 1, randomized, placebo controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel, Natalia Teleshova, Marla J. Keller, José Fernández-Romero, Barbara Friedland, George W. Creasy, Marlena Gehret Plagianos, Laurie Ray, Patrick Barnable, Larisa Kizima, Aixa Rodriguez, Nadjet Cornejal, Claudia Melo, Gearoff Cruz Rodriguez, Sampurna Mukhopadhyay, Giulia Calenda, Shweta U. Sinkar, Thierry Bonnaire, Asa Wesenberg, Shimin Zhang, Kyle Kleinbeck, Kenneth Palmer, Mohcine Alami, Barry R. O'Keefe, Patrick Gillevet, Hong Hur, Yupu Liang, Gabriela Santone, Raina N. Fichorova, Tamara Kalir, and Thomas Zydowsky

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Role of laminin and collagen chains in human spermatogenesis—Insights from studies in rodents and scRNA-Seq transcriptome profiling, Xiaolong Wu, Sheng Gao, Lingling Wang, Tiao Bu, Siwen Wu, Liwei Zhou, Jie Shi, Di Wu, Fei Sun, and C. Yan Cheng