The Population Council’s Center for Biomedical Research (CBR) is a vibrant hub of scientific investigation and product development. Our scientists address critical questions in reproductive health and develop innovative products that protect the health and well-being of millions of people worldwide. CBR is located at Rockefeller University in New York City.

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Submissions from 2024

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Ex vivo colonic tissue susceptibility to HIV-1 in cisgender men and women, Patrick Barnable, Sampurna Mukhopadhyay, Larisa Kizima, Narender Kumar, Marlena Gehret Plagianos, Saurabh Mehandru, and Natalia Teleshova

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Risk factors for and outcomes of ring expulsions with a one year contraceptive vaginal system, Marlena Gehret Plagianos, Shaalini Ramanadhan, Ruth Merkatz, Vivian Brache, Barbara Friedland, and Lisa Haddad

Submissions from 2023

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Adherence, safety, and choice of the monthly dapivirine vaginal ring or oral emtricitabine plus tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis among African adolescent girls and young women: A randomised, open-label, crossover trial, Gonasagrie Nair, Connie Celum, Daniel Szydlo, Elizabeth R. Brown, Carolyne Akello, Rita Nakalega, et al., and John Steytler

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Baseline preferences for oral pre-exposure prophylaxis (PrEP) or dapivirine intravaginal ring for HIV prevention among adolescent girls and young women in South Africa, Uganda and Zimbabwe (MTN-034/IPM-045 study), Kenneth Ngure, Barbara Friedland, Daniel W. Szydlo, Sarah Roberts, Morgan Garcia, Lisa Levy, Carolyne Akello, Krishnaveni Reddy, Thesla Palanee-Phillips, Pippa Macdonald, Bekezela Siziba, Lydia Soto-Torres, Sybil Hosek, Sharon L. Hillier, Gonasagrie Nair, Connie Celum, and Ariane van der Straten

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Center for Biomedical Research at the Population Council, Population Council

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Characterization of viruses in Phase 3 and Phase 3b trials (the Ring Study and the Dapivirine Ring Extended Access and Monitoring Trial) of the Dapivirine vaginal ring for human immunodeficiency virus type 1 infection risk reduction, John Steytler, Charles Craig, Elna van der Ryst, Ben Van Baelen, Jeremy Nuttall, Neliette van Niekerk, John Mellors, Urvi Parikh, and Carole Wallis

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Clinical presentation, treatment response, and virology outcomes of women who seroconverted in the Dapivirine Vaginal Ring Trials—The Ring Study and DREAM, John Steytler, Elna van der Ryst, Charles Craig, Ben Van Baelen, Jeremy Nuttall, Neliette van Niekerk, John Mellors, Urvi Parikh, and Carole Wallis

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Coming Full Circle: Microbicide Development at the Population Council, James Sailer, Barbara Friedland, Diantha Pillay, Christopher J. Elias, Sharon L. Hillier, and Georgina Caswell

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Commentary: Multipurpose prevention technologies—What about sexually transmitted infections?, Anjanique Mariquit Rosete Lu and Lisa Haddad

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Deep eutectic solvents for subcutaneous delivery of protein therapeutics, Alexander M. Curreri, Jayoung Kim, Michael Dunne, Pavimol Angsantikul, Morgan Goetz, Yongsheng Gao, and Samir Mitragotri

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Design of an international male contraceptive efficacy trial using a self-administered daily transdermal gel containing testosterone and segesterone acetate (Nestorone), John K. Amory, Diana Blithe, Régine Sitruk-Ware, Ronald S. Swerdloff, William J. Bremner, Clint Dart, Peter Y. Liu, Arthi Thirumalai, Brian T. Nguyen, Bradley D. Anawalt, Min S. Lee, Stephanie T. Page, and Christina Wang

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Development of mucoadhesive electrospun scaffolds for intravaginal delivery of Lactobacilli spp., a tenside, and metronidazole for the management of bacterial vaginosis, Margaret O. Ilomuanya, Peace O. Bassey, Deborah A. Ogundemuren, Uloma N. Ubani-Ukoma, Alkiviadis Tsamis, Yuwei Fan, Konstantinos Michalakis, Pavimol Angsantikul, Abdulrahman Usman, and Andrew N. Amenaghawon

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Does size matter? A randomized controlled trial to assess the impact of external diameter on adherence to 3 different intravaginal rings among 24 US couples, Irene Bruce, Marlena Gehret Plagianos, Jessica M. Sales, Jessica Atrio, Shakti Shetty, Caio Sant’Anna Marinho, Brady Zieman, Lisa Haddad, and Barbara Friedland

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Drug reprofiling to identify potential HIV-1 protease inhibitors, Sunday Okafor, Abigail Meyer, Jay Gadsden, Fadi Ahmed, Lilian Guzmán, Hashim Ahmed, José Fernández-Romero, and Pavimol Angsantikul

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Equipping providers to offer novel MPTs: Developing counseling messages for the Dual Prevention Pill in clinical studies and beyond, Kate Segal, Danielle M. Harris, Andy Carmone, Lisa Haddad, Sanjay Hadigal, Karin Hatzold, Chris Jones, Eva Lathrop, Jennifer Mason, and Meridith Mikulich

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Evaluating the association of antiretroviral therapy and immune status with hypertensive disorders of pregnancy among people with HIV, Lynn M. Yee, Denise L. Jacobson, Lisa Haddad, Jennifer Jao, Kathleen M. Powis, Deborah Kacanek, Rebecca Zash, Alexandria Diperna, and Ellen G. Chadwick

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Exploring user and stakeholder perspectives from South Africa and Uganda to refine microarray patch development for HIV PrEP delivery and as a multipurpose prevention technology, Ayesha Ismail, Sarah Magni, Anne Katahoire, Florence Ayebare, Godfrey Siu, Fred Semitala, Peter Kyambadde, Barbara Friedland, Courtney Jarrahian, and Maggie Kilbourne-Brook

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Gestational weight gain in persons with HIV in the United States, Jennifer Jao, Deborah Kacanek, Carly Broadwell, Denise L. Jacobson, Ellen G. Chadwick, Paige L. Williams, Kathleen Powis, Lisa Haddad, and Lynn Yee

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Herpes simplex virus type 2 prevalence and association with inflammatory cytokines among sexual and gender minorities living with and without HIV-1 from Lagos, Nigeria, Meropi Aravantinou, Marlena Gehret Plagianos, Afoke Kokogho, Sylvia Adebajo, Rebecca G. Nowak, Elizabeth Shoyemi, Charles Ekeh, Kara Lombardi, Sheila Peel, Stefan Baral, Trevor A. Crowell, Nina Derby, Natalia Teleshova, and Elena Martinelli

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Influence of hormonal contraceptive use and HIV on cervicovaginal cytokines and microbiota in Malawi, Lisa Haddad, Jennifer H. Tang, Nicole L. Davis, Athena P. Kourtis, Lameck Chinula, Albans Msika, Gerald Tegha, Mina C. Hosseinipour, Julie A.E. Nelson, Marcia M. Hobbs, Pawel Gajer, Jacques Ravel, and Kristina De Paris

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New approaches for developing biomarkers of hormonal contraceptive use, Rakhee Sachdeva, Narender Kumar, Vivian Brache, Barbara Friedland, Marlena Gehret Plagianos, Shimin Zhang, Larisa Kizima, Leila Cochon, Ana Sofía Tejada Tabar, Ann K. Blanc, and Ruth Merkatz

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Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a Phase 1 clinical trial: Learning from users to improve acceptability, Mary Kate Shapley-Quinn, Mei Song, Beatrice A. Chen, Brid Devlin, Ellen Luecke, Jill Brown, Diana Blithe, Sharon Achilles, and Ariane van der Straten

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Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines, Christina Wang, M. Cristina Meriggiola, John K. Amory, Christopher L.R. Barratt, Hermann M. Behre, William J. Bremner, Alberto Ferlin, Stanton Honig, Zsolt Kopa, Kirk C. Lo, Eberhard Nieschlag, Stephanie T. Page, Jay Sandlow, Régine Sitruk-Ware, Ronald S. Swerdloff, Frederick C.W. Wu, and Dimitrios G. Goulis

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Unique profile of inflammation and immune activation in pregnant people with HIV in the United States, Stephanie Shiau, Denise L. Jacobson, Yanling Huo, Deborah Kacanek, Lynn M. Yee, David B. Williams, Lisa Haddad, Lena Serghides, Kathleen M. Powis, Rhoda Sperling, Paige L. Williams, Jennifer Jao, and Pediatric HIV/AIDS Cohort Study (PHACS)

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Vaginal microbiome, antiretroviral concentrations, and HIV genital shedding in the setting of hormonal contraception initiation in Malawi, Alyssa M. Lantz, Mackenzie L. Cottrell, Amanda H. Corbett, Lameck Chinula, Athena P. Kourtis, Julie A.E. Nelson, Gerald Tegha, Stacey Hurst, Pawel Gajer, Jacques Ravel, Lisa Haddad, Jennifer H. Tang, and Melanie R. Nicol

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Women want choices: Opinions from the Share.Learn.Shape global internet survey about multipurpose prevention technology (MPT) products in development, Barbara Friedland, Marlena Gehret Plagianos, Craig Savel, Virginia Kallianes, C. Martinez, Lorna Begg, K.M. Guthrie, D. Venkatasetty, J. Pickett, and Lisa Haddad

Submissions from 2022

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Acceptability of PC-1005 gel administered rectally to HIV-1 seronegative adults at three different volume levels (MTN-037), José A. Bauermeister, Ryan C. Tingler, Ken Ho, Rachel Scheckter, Tara McClure, Jontraye Davis, Jeanna Piper, Barbara Friedland, Stacey Edick, Mei Song, Yuqing Jiao, Craig W. Hendrix, and Craig Hoesley

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A content analysis of Reddit users’ posts about challenges to contraceptive care-seeking during COVID-19-related restrictions in the United States, Zoe H. Pleasure, Lori F. Frohwirth, Naomi Li, and Chelsea Polis

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A mixed-methods study of factors influencing postpartum intrauterine device uptake after family planning counseling among women in Kigali, Rwanda, Mariama S. Tounkara, Rosine Ingabire, Dawn L. Comeau, Etienne Karita, Susan Allen, Julien Nyombayire, Rachel Parker, Lisa Haddad, Vanessa Da Costa, Amanda Tichacek, Amelia Mazzei, Jeannine Mukamuyango, and Kristin M. Wall

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Antiviral activity of aframomum melegueta against severe acute respiratory syndrome coronaviruses type 1 and 2, Oneil Mahoney, Claudia Melo, Anthony Lockhart, Nadjet Cornejal, Sahar Alsaidi, Qingli Wu, Jim Simon, Rodolfo Juliani, Thomas Zydowsky, Christine Priano, Adolfina Koroch, and José Fernández-Romero

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Biomimetic targeted theranostic nanoparticles for breast cancer treatment, Suphalak Khamruang Marshall, Pavimol Angsantikul, Zhiqing Pang, Norased Nasongkla, Rusnah Syahila Duali Hussen, and Soracha Dechaumpahi Thamphiwatana

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Bone, Brain, Heart study protocol: A resilient nested, tripartite prospective cohort study of the role of estrogen depletion on HIV pathology, C. Christina Mehta, Kimberly S. Hagen, Anna A. Rubtsova, Cecile D. Lahiri, Vasiliki Michopoulos, Caitlin A. Moran, Lisa Haddad, Kehmia Titanji, Lauren F. Collins, Arshed A. Quyyumi, Gretchen Neigh, Leslee J. Shaw, M. Neale Weitzmann, Lance Waller, and Ighovwerha Ofotokun

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Contraceptive drug, Nestorone, enhances stem cell-mediated remodeling of the stroke brain by dampening inflammation and rescuing mitochondria, Jea-Young Lee, Vanessa Castelli, Narender Kumar, Régine Sitruk-Ware, and Cesario V. Borlongan

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Discovery of novel HIV protease inhibitors using modern computational techniques, Sunday Okafor and Pavimol Angsantikul

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Discovery of novel HIV protease inhibitors using modern computational techniques, Sunday Okafor, Pavimol Angsantikul, and Hashim Ahmed

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Drug repurposing for HIV-1 protease inhibitors: High throughput virtual screening, rigid molecular docking and molecular dynamics studies, Sunday Okafor, Pavimol Angsantikul, and Hashim Ahmed

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Essential oils block cellular entry of SARS-CoV-2 delta variant, Luiz Torres Neto, Maria Lúcia Guerra Monteiro, José Fernández-Romero, Natalia Teleshova, James Sailer, and Carlos Adam Conte Junior

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Estradiol inhibits HIV-1BaL infection and induces CFL1 expression in peripheral blood mononuclear cells and endocervical mucosa, Neeharika Verma, Sampurna Mukhopadhyay, Patrick Barnable, Marlena Gehret Plagianos, and Natalia Teleshova

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Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): A prospective cohort study protocol, Lisa Haddad, Gina Bailey Herring, C. Christina Mehta, Tyree Staple, Marisa R. Young, Sakthivel Govindaraj, Vijayakumar Velu, and Alicia K. Smith

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Exposed and sequestered antigens in testes and their protection by regulatory T cell-dependent systemic tolerance, Jessica Harakal, Hui Qiao, Karen Wheeler, Claudia Rival, Alberta G.A. Paul, Daniel M. Hardy, C. Yan Cheng, Erwin Goldberg, and Kenneth S.K. Tung

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Freeze-drying for the preservation of immunoengineering products, Nagavendra Kommineni, Arun Butreddy, Vaskuri G.S. Sainaga Jyothi, and Pavimol Angsantikul

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High throughput scRNA-Seq provides insights into leydig cell senescence induced by experimental autoimmune orchitis: A prominent role of interstitial fibrosis and complement activation, Yinchuan Li, Panpan Mi, Jiabao Wu, Yunge Tang, Xiaohua Liu, Jinmei Cheng, Yingying Huang, Weibing Qin, C. Yan Cheng, and Fei Sun

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Implementation and evaluation of a large-scale postpartum family planning program in Rwanda: Study protocol for a clinic-randomized controlled trial, Kristin M. Wall, Rosine Ingabire, Amelia Mazzei, Claudine Umuhoza, Rachel Parker, Amanda Tichacek, Azhar Nizam, Jessica M. Sales, Lisa Haddad, Phaedra Corso, Susan Allen, Julien Nyombayire, and Etienne Karita

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Incidence and characteristics of stillbirths before and during the Coronavirus 2019 pandemic, Kavita Vani, Fatima Estrada Trejo, Marlena Gehret Plagianos, Morit Segui, Thammatat Vorawandthanachai, Lisa Nathan, and Francine Hughes

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MARK2 and MARK4 regulate Sertoli cell BTB dynamics through microtubule and actin cytoskeletons, Elizabeth I. Tang and C. Yan Cheng

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Measuring potential interest in a postpartum contraceptive vaginal ring among breastfeeding women in India, Lorna Begg, James Sailer, Avishek Hazra, Malabika Roy, Ruth Merkatz, Lisa Haddad, Rebecca Brodsky, and John Bongaarts

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mTORC1/rpS6 and p-FAK-Y407 signaling regulate spermatogenesis: Insights from studies of the adjudin pharmaceutical/toxicant model, Lingling Wang, Linxi Li, Xiaolong Wu, Chris K.C. Wong, Adolfo Perrotta, Bruno Silvestrini, Fei Sun, and C. Yan Cheng

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Nestorone nanosuspension-loaded dissolving microneedles array patch: A promising novel approach for “on-demand” hormonal female-controlled peritcoital contraception, Ebru Altuntaş, Ismaiel A. Tekko, Lalitkumar K. Vora, Narender Kumar, Rebecca Brodsky, Olivier Chevallier, Emma McAlister, Qonita Kurnia Anjani, Helen O. McCarthy, and Ryan F. Donnelly

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Progress in male contraception: A brief summary of the Third International Congress on Male Contraception, May 2022, Christina Wang, Diana Blithe, Stephanie Page, David Serfaty, and Régine Sitruk-Ware

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Recap of the Sixth International Symposium on Intrauterine Devices and Systems for Women's Health, Rachel Ferat, Lisa Haddad, Carolyn Westhoff, and David Hubacher

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Results of a phase 1, randomized, placebo controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel, Natalia Teleshova, Marla J. Keller, José Fernández-Romero, Barbara Friedland, George W. Creasy, Marlena Gehret Plagianos, Laurie Ray, Patrick Barnable, Larisa Kizima, Aixa Rodriguez, Nadjet Cornejal, Claudia Melo, Gearoff Cruz Rodriguez, Sampurna Mukhopadhyay, Giulia Calenda, Shweta U. Sinkar, Thierry Bonnaire, Asa Wesenberg, Shimin Zhang, Kyle Kleinbeck, Kenneth Palmer, Mohcine Alami, Barry R. O'Keefe, Patrick Gillevet, Hong Hur, Yupu Liang, Gabriela Santone, Raina N. Fichorova, Tamara Kalir, and Thomas Zydowsky

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Role of laminin and collagen chains in human spermatogenesis—Insights from studies in rodents and scRNA-Seq transcriptome profiling, Xiaolong Wu, Sheng Gao, Lingling Wang, Tiao Bu, Siwen Wu, Liwei Zhou, Jie Shi, Di Wu, Fei Sun, and C. Yan Cheng

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Sexually transmitted infections in pregnant people with human immunodeficiency virus: Temporal trends, demographic correlates, and association with preterm birth, Marisa R. Young, Carly Broadwell, Deborah Kacanek, Ellen G. Chadwick, Jennifer Jao, Anna Barbara Moscicki, Kathleen Powis, Katherine Tassiopoulos, Lynn M. Yee, and Lisa Haddad

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ShangRing versus Mogen clamp for early infant male circumcision in eastern sub-Saharan Africa: A multicentre, non-inferiority, adaptive, randomised controlled trial, Spyridon P. Basourakos, Quincy G. Nang, Karla V. Ballman, Omar Al Hussein Al Awamlh, Nahid Punjani, Kaylee Ho, Mark Barone, Quentin Awori, Daniel Ouma, Jairus Oketch, Alice E. Christensen, Augustino Hellar, Maende Makokha, Alphonce Isangu, Robert Salim, Jackson Lija, Ronald H. Gray, Stephen Kiboneka, Aggrey Anok, Godfrey Kigozi, Regina Nakabuye, Charles Ddamulira, Andrew Mulooki, Silas Odiya, Rose Nazziwa, Marc Goldstein, Philip S. Li, and Richard K. Lee

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Small molecules targeting SARS-CoV-2 spike glycoprotein receptor-binding domain, Yoel Rodriguez, Scarlet Martínez Cardoze, Onyinyechi W. Obineche, Claudia Melo, Ashanna Persaud, and José Fernández-Romero

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SNAC for enhanced oral bioavailability: An updated review, Nagavendra Kommineni, Vaskuri G.S. Sainaga Jyothi, Arun Butreddy, Saka Raju, Tovi Shapira, Wahid Khan, Pavimol Angsantikul, and Abraham J. Domb

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“They're forcing people to have children that they can't afford”: A qualitative study of social support and capital among individuals receiving an abortion in Georgia, Madison S. Dickey, Elizabeth A. Mosley, Elizabeth A. Clark, Sarah Cordes, Eva Lathrop, and Lisa Haddad

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Transport and permeation properties of dapivirine: Understanding potential drug-drug interactions, Ruohui Zheng, Guru R. Valicherla, Junmei Zhang, Jeremy Nuttall, Peter Silvera, Leslie J. Marshall, Philip E. Empey, and Lisa C. Rohan

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Trichomonas vaginalis and spontaneous preterm birth in a high-risk obstetric cohort in Atlanta, GA, Marisa R. Young, Kristin M. Wall, Carolynn M. Dude, Emily R. Burdette, Denise J. Jamieson, Igho Ofotokun, and Lisa Haddad

Submissions from 2021

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Addressing contraceptive needs exacerbated by COVID-19: A call for increasing choice and access to self-managed methods, Lisa Haddad, Saumya RamaRao, Avishek Hazra, Harriet Birungi, and James Sailer

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AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis, Siwen Wu, Linxi Li, Xiaolong Wu, Chris K.C. Wong, Fei Sun, and C. Yan Cheng

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Algal and cyanobacterial lectins and their antimicrobial properties, José Fernández-Romero, Maria Gabriela Paglini, Christine Priano, Adolfina Koroch, Yoel Rodriguez, James Sailer, and Natalia Teleshova

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A local regulatory network in the testis mediated by laminin and collagen fragments that supports spermatogenesis, Linxi Li, Huitao Li, Lingling Wang, Tiao Bu, Shiwen Liu, Baiping Mao, and C. Yan Cheng

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An in vitro assay to monitor sertoli cell blood-testis barrier (BTB) integrity, Siwen Wu, Lingling Wang, Elizabeth I. Tang, Junlu Wang, and C. Yan Cheng

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Antioxidant, antibacterial, and anti-SARS-CoV activity of commercial products of Xylopia (Xylopia aethiopica), Claudia Melo, Rosemary Perdomo, Fadel Yerima, Oneil Mahoney, Nadjet Cornejal, Sahar Alsaidi, Sahar Coron, Thierry Bonnaire, Shimin Zhang, Thomas Zydowsky, Christine Priano, José Fernández-Romero, Rodolfo Juliani, and Adolfina Koroch

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Antioxidant capacity and antimicrobial activity of commercial samples of guava leaves, Claudia Melo, Nadjet Cornejal, Victor Cruz, Sahar Alsaidi, Gearoff Cruz Rodriguez, Aned Gomez Ramirez, Victor Sorel, Thierry Bonnaire, Thomas Zydowsky, Christine Priano, José Fernández-Romero, and Adolfina Koroch

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Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodies, Ines Frank, Maria Sole Cigoli, Muhammad Shafique Arif, Marissa D. Fahlberg, Stephanie Maldonado, Giulia Calenda, Amarendra Pegu, Eun Sung Yang, Reda Rawi, Gwo-Yu Chuang, Hui Geng, Cuiping Liu, Tongqing Zhou, Peter D. Kwong, James Arthos, Claudia Cicala, Brooke Grasperge, James L. Blanchard, Agegnehu Gettie, Christine M. Fennessey, Brandon F. Keele, Monica Vaccari, Thomas J. Hope, Anthony S. Fauci, John R. Mascola, and Elena Martinelli

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Contraception au futur: Nouvelles techniques à l’horizon de la prochaine décennie, Régine Sitruk-Ware

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Contraception methods used among women with HIV starting antiretroviral therapy in a large United States clinical trial, 2009–2011, Anandi N. Sheth, Christine D. Angert, Lisa Haddad, C. Christina Mehta, and Susan E. Cohn

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Contraceptive technologies: Looking ahead to new approaches to increase options for family planning, Lisa Haddad, John Townsend, and Régine Sitruk-Ware

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Dissecting mammalian spermatogenesis using spatial transcriptomics, Haiqi Chen, Evan Murray, Anubhav Sinha, Jilong Li, Daniel Lesman, Xichen Nie, Jim Hotaling, Jingtao Guo, Bradley R. Cairns, Evan Z. Macosko, C. Yan Cheng, and Fei Chen

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Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis, Yinchuan Li, Panpan Mi, Xue Chen, Jiabao Wu, Weibing Qin, Yiqi Shen, Pingbao Zhang, Yunge Tang, C. Yan Cheng, and Fei Sun

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Estimating the market size for a dual prevention pill: Adding contraception to pre-exposure prophylaxis (PrEP) to increase uptake, Lorna Begg, Rebecca Brodsky, Barbara Friedland, Sanyukta Mathur, James Sailer, and George W. Creasy

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Griffithsin and carrageenan combination results in antiviral synergy against SARS-CoV-1 and 2 in a pseudoviral model, Sahar Alsaidi, Nadjet Cornejal, Oneil Mahoney, Claudia Melo, Neeharika Verma, Thierry Bonnaire, Theresa Chang, Barry R. O'Keefe, James Sailer, Thomas Zydowsky, Natalia Teleshova, and José Fernández-Romero

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Harnessing the power of partnership to advance reproductive health and rights, Julia Bunting and Régine Sitruk-Ware

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HIV-1 establishes a sanctuary site in the testis by permeating the BTB through changes in cytoskeletal organization, Siwen Wu, Ines Frank, Nina Derby, Elena Martinelli, and C. Yan Cheng

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KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin and septin cytoskeletons, Siwen Wu, Lixiu Lv, Linxi Li, Lingling Wang, Baiping Mao, Jun Li, Xian Shen, Renshan Ge, Chris K.C. Wong, Fei Sun, and C. Yan Cheng

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Marijuana, opioid, and alcohol use among pregnant and postpartum individuals living with HIV in the US, Lynn M. Yee, Deborah Kacanek, Chase Brightwell, Lisa Haddad, Jennifer Jao, Kathleen M. Powis, Tzy-Jyun Yao, Emily Barr, Carly Broadwell, Suzanne Siminski, George R. Seage, Ellen G. Chadwick, and Pediatric HIV/AIDS Cohort Study (PHACS)

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Marijuana, opioid, and alcohol use among pregnant and postpartum individuals living with HIV in the US, Lynn M. Yee, Deborah Kacanek, Chase Brightwell, Lisa Haddad, Jennifer Jao, Kathleen M. Powis, Tzy-Jyun Yao, Emily Barr, Carly Broadwell, Suzanne Siminski, George R. Seage, Ellen G. Chadwick, and Pediatric HIV/AIDS Cohort Study (PHACS)

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Microtubule-associated proteins (MAPs) in microtubule cytoskeletal dynamics and spermatogenesis, Lingling Wang, Ming Yan, Chris K.C. Wong, Renshan Ge, Xiaolong Wu, Fei Sun, and C. Yan Cheng

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Motor proteins and spermatogenesis, Siwen Wu, Huitao Li, Lingling Wang, Nathan Mak, Xiaolong Wu, Renshan Ge, Fei Sun, and C. Yan Cheng

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NC1-peptide derived from collagen α3 (IV) chain is a blood-tissue barrier regulator: Lesson from the testis, Shiwen Liu, Huitao Li, Renshan Ge, and C. Yan Cheng

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Nestorone®, a 19nor‐progesterone derivative boosts remyelination in an animal model of demyelination, Martine El-Etr, Yvette Akwa, Marion Rame, Michael Schumacher, and Régine Sitruk-Ware

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Pharmacodynamics and pharmacokinetics of a copper intrauterine contraceptive system releasing ulipristal acetate: A randomized proof-of-concept study, Vivian Brache, Carolina Sales Vieira, Marlena Gehret Plagianos, Maud Lansiaux, Ruth Merkatz, Heather Sussman, Leila Cochon, Ana-Sofia Tejada, Narender Kumar, Dan Loeven, Diana Blithe, Abi Santhosh Aprem, Alistair Williams, Athilakshmi Kannan, Indrani C. Bagchi, and Régine Sitruk-Ware

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Polymorphism characterization of segesterone acetate: A comprehensive study using XRPD, FT-IR and Raman spectroscopy, Fermin F.H. Aragon, Clement M. Haeck, Paulo C. Morais, and Bruce Variano

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Progress in progestin-based therapies for neurological disorders, Régine Sitruk-Ware, Brooke Bonsack, Roberta Diaz Brinton, Michael Schumacher, Narender Kumar, Jea-Young Lee, Vanessa Castelli, Sydney Corey, Alexandreya Coats, Nadia Sadanandan, Bella Gonzales-Portillo, Matt Heyck, Alex Shear, Cozene Blaise, Henry Zhang, Michael Sheyner, Julián García-Sánchez, Lisset Navarro, Martine El-Etr, Alejandro De Nicola, and Cesario V. Borlongan

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Segesterone acetate serum levels with a regression model of continuous use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system, James Liu, Marlena Gehret Plagianos, David F. Archer, James A. Simon, Andrew M. Kaunitz, Shelli Graham, Brian Bernick, and Sebastian Mirkin

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Sex differences in the cerebroprotection by Nestorone intranasal delivery following stroke in mice, Magalie Fréchou, Xiaoyan Zhu, Narender Kumar, Régine Sitruk-Ware, Michael Schumacher, Claudia Mattern, and Rachida Guennoun

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Tex13a optimizes sperm motility via its potential roles in mRNA turnover, Yinchuan Li, Panpan Mi, Xue Chen, Jiabao Wu, Xiaohua Liu, Yunge Tang, Jinmei Cheng, Yingying Huang, Weibing Qin, and C. Yan Cheng

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The effect of antiretroviral therapy for the treatment of human immunodeficiency virus (HIV)-1 in pregnancy on gestational weight gain, Naima T. Joseph, Glen A. Satten, Rachel E. Williams, Lisa Haddad, Denise J. Jamieson, Anandi N. Sheth, and Martina L. Badell

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The non-hormonal male contraceptive adjudin exerts its effects via MAPs and signaling proteins mTORC1/rpS6 and FAK-Y407, Lingling Wang, Ming Yan, Huitao Li, Siwen Wu, Renshan Ge, Chris K.C. Wong, Bruno Silvestrini, Fei Sun, and C. Yan Cheng

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The promise of the dual prevention pill: A framework for development and introduction, Barbara Friedland, Sanyukta Mathur, and Lisa Haddad

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The vaginal microbiota, bacterial biofilms and polymeric drug-releasing vaginal rings, Louise Carson, Ruth Merkatz, Elena Martinelli, Peter Boyd, Bruce Variano, Teresa Sallent, and R. Karl Malcolm

Submissions from 2020

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Actin binding proteins, actin cytoskeleton and spermatogenesis—Lesson from toxicant models, Lingling Wang, Ming Yan, Siwen Wu, Xiaolong Wu, Tiao Bu, Chris K.C. Wong, Renshan Ge, Fei Sun, and C. Yan Cheng

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An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy, Yu-Qian Wang, Jin-Mei Cheng, Qing Wen, Ji-Xin Tang, Jian Li, Su-Ren Chen, and Yi-Xun Liu

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Anti-α4β7 monoclonal antibody–conjugated nanoparticles block integrin α4β7 on intravaginal T cells in rhesus macaques, Sidi Yang, Geraldine Arrode-Bruses, Ines Frank, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Elena Martinelli, and Emmanuel A. Ho

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Bioactive fragments of laminin and collagen chains—Lesson from the testis, Huitao Li, Shiwen Liu, Siwen Wu, Linxi Li, Renshan Ge, and C. Yan Cheng

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Chagas disease screening using point-of-care testing in an at-risk obstetric population, Lindsey E. Zamora, Federico Palacio, Debra S. Kozlowski, Kamini Doraivelu, Carolynn M. Dude, Denise J. Jamieson, and Lisa Haddad

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Crosstalk between Sertoli and germ cells in male fertility, Siwen Wu, Ming Yan, Renshan Ge, and C. Yan Cheng

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Dose-finding study of a 90-day contraceptive vaginal ring releasing estradiol and segesterone acetate, Melissa J. Chen, Mitchell Creinin, David K. Turok, David F. Archer, Kurt T. Barnhart, Carolyn Westhoff, Michael A. Thomas, Jeffrey T. Jensen, Bruce Variano, Régine Sitruk-Ware, Anita Shanker, Jill Long, and Diana Blithe