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Submissions from 2010

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Deletion of the Igf1 gene: Suppressive effects on adult Leydig cell development, Guo-Xin Hu, Han Lin, Guo-Rong Chen, Bing-Bing Chen, Qing-Quan Lian, Dianne O. Hardy, Barry R. Zirkin, and Renshan Ge

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Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood–testis barrier, Linlin Su, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Endometrial effect of progesterone delivered by vaginal rings in estrogen-treated postmenopausal women, Gabriela Noe; Régine Sitruk-Ware; Fernando Zegers-Hochschild; Bruce Variano; Juan Carlos Montero; P. Arriagada; A. Li; Frank Z. Stanczyk; J.C. Felix; Daniel R. Mishell, Jr.; and Horacio B. Croxatto

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Glucocorticoid suppresses steroidogenesis in rat progenitor Leydig cells, Ye-Chen Xiao, Ya-Dong Huang, Dianne O. Hardy, Xiao-Kun Li, and Renshan Ge

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Inhibition of 3β- and 17β-hydroxysteroid dehydrogenase activities in rat Leydig cells by perfluorooctane acid, Binghai Zhao, Yanhui Chu, Dianne O. Hardy, Xiao-Kun Li, and Renshan Ge

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Inhibition of LH-stimulated androgen production in rat immature Leydig cells: Effects on nuclear receptor steroidogenic factor 1 by FGF2, Ye-Chen Xiao, Dianne O. Hardy, Chantal M. Sottas, Xiao-Kun Li, and Renshan Ge

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Intrauterine administration of CDB-2914 (Ulipristal) suppresses the endometrium of rhesus macaques, Robert M. Brenner, Ov D. Slayden, Anita Nath, Yun-yen Tsong, and Régine Sitruk-Ware

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In vivo binding and retention of CD4-Specific DARPin 57.2 in macaques, Pavel Pugach, Anders Krarup, Agegnehu Gettie, Marcelo Kuroda, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, Alexandra Trkola, and Melissa Robbiani

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New frontiers in nonhormonal male contraception, C. Yan Cheng and Dolores D. Mruk

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New frontiers in nonhormonal male contraception, C. Yan Cheng and Dolores D. Mruk

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No-needle local anesthesia for adult male circumcision, Yifeng Peng, Puneet Masson, Philip S. Li, Yue Chang, Long Tian, Richard Lee, Howard H. Kim, David C. Sokal, and Marc Goldstein

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Perinatal exposure to di-(2-ethylhexyl) phthalate leads to restricted growth and delayed lung maturation in newborn rats, Shang-Qin Chen, Jin-Ni Chen, Xiao-Hong Cai, Guo-Rong Chen, Yuan Gao, Renshan Ge, Hai-Shan Wu, Zhen-Lang Lin, and Jing Lin

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Progesterone vaginal ring for contraceptive use during lactation, Anita Nath and Régine Sitruk-Ware

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Regulation of blood–testis barrier dynamics by TGF-β3 is a Cdc42-dependent protein trafficking event, Elissa W.P. Wong, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: New insights and advances, C. Yan Cheng, Elissa W.P. Wong, Helen H.N. Yan, and Dolores D. Mruk

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Restricted Arp3 expression in the testis prevents blood–testis barrier disruption during junction restructuring at spermatogenesis, Pearl P.Y. Lie, Apple Y.N. Chan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Sertoli-germ cell junctions in the testis: A review of recent data, Ilona A. Ropera, Barbara Bilinska, C. Yan Cheng, and Dolores D. Mruk

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Single-dose Pharmacokinetics of Nestorone®, a potential female-contraceptive, Pramod Vishwanath Prasad, Mohammad Bashir, Régine Sitruk-Ware, and Narender Kumar

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Single-dose Pharmacokinetics of Nestorone®, a potential female-contraceptive, Pramod Vishwanath Prasad, Mohammad Bashir, Régine Sitruk-Ware, and Narender Kumar

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State-of-the-art of non-hormonal methods of contraception: III. Intrauterine devices, Irving Sivin and I. Batar

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State-of-the-art of non-hormonal methods of contraception: III. Intrauterine devices, Irving Sivin and I. Batar

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State-of-the-art of non-hormonal methods of contraception: I. Mechanical barrier contraception, I. Batar and Irving Sivin

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State-of-the-art of non-hormonal methods of contraception: I. Mechanical barrier contraception, I. Batar and Irving Sivin

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State-of-the-art of non-hormonal methods of contraception: IV. Natural family planning, G. Freundl, Irving Sivin, and I. Batar

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State-of-the-art of non-hormonal methods of contraception: IV. Natural family planning, G. Freundl, Irving Sivin, and I. Batar

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Structure-dependent inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 activities by phthalates, Binghai Zhao, Yanhui Chu, Ya-Dong Huang, Dianne O. Hardy, Shaoqiang Lin, and Renshan Ge

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The annulus of the mouse sperm tail is required to establish a membrane diffusion barrier that is engaged during the late steps of spermiogenesis, Susanna Kwitny, Angela V. Klaus, and Gary R. Hunnicutt

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The biology of spermatogenesis: The past, present and future, C. Yan Cheng and Dolores D. Mruk

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The use of newer progestins for contraception, Régine Sitruk-Ware and Anita Nath

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The use of newer progestins for contraception, Régine Sitruk-Ware and Anita Nath

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Tight junctions in the testis: New perspectives, Dolores D. Mruk and C. Y. Cheng

Submissions from 2009

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14-3-3 and its binding partners are regulators of protein-protein interactions during spermatogenesis, Shengyi Sun, Elissa W.P. Wong, Michelle W.M. Li, Will M. Lee, and C. Yan Cheng

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14-3-3 protein regulates cell adhesion in the seminiferous epithelium of rat testes, Elissa W.P. Wong, Shengyi Sun, Michelle W.M. Li, Will M. Lee, and C. Yan Cheng

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Acceptability of a Carrageenan-based candidate vaginal microbicide and matching placebo: Findings from a Phase II safety trial among women in Chiang Rai, Thailand, Heidi E. Jones, Supaporn Chaikummao, Janneke van de Wijgert, Barbara Friedland, Chomnad Manopaiboon, Paisit Witwatwongwana, Mayuree Wankrairot, Nartlada Chantharojwong, and Peter H. Kilmarx

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Activins regulate 17β-hydroxysteroid dehydrogenase type I transcription in murine gonadotrope cells, Beata Bak, Laura Carpio, Jinjing L. Kipp, Pankaj Lamba, Ying Wang, Renshan Ge, Matthew P. Hardy, Kelly E. Mayo, and Daniel J. Bernard

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A decision analysis of treatments for nonobstructive azoospermia associated with varicocele, Richard Lee, Philip S. Li, Marc Goldstein, Glenn Schattman, and Peter N. Schlegel

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Adjudin targeting rabbit germ cell adhesion as a male contraceptive: A pharmacokinetics study, Guo-Xin Hu, Lu-Feng Hu, Dai-Zheng Yang, Jun-Wei Li, Guo-Rong Chen, Bing-Bing Chen, Dolores D. Mruk, Michele Bonanomi, Bruno Silvestrini, C. Yan Cheng, and Renshan Ge

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A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy, Federica Crostarosa, Meropi Aravantinou, Onome J. Akpogheneta, Edith Jasny, Andrew Shaw, Jessica Kenney, Michael Piatak Jr., Jeffrey D. Lifson, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M. Zydowsky, James Blanchard, Agegnehu Gettie, and Melissa Robbiani

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An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: A biochemical and molecular perspective, C. Yan Cheng and Dolores D. Mruk

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An in vivo study on adjudin and blood-testis barrier dynamics, Ilona A. Kopera, Linlin Su, Barbara Bilínska, C. Yan Cheng, and Dolores D. Mruk

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An occludin-focal adhesion kinase protein complex at the blood-testis barrier: A study using the cadmium model, Erica R. Siu, Elissa W.P. Wong, Dolores D. Mruk, K.L. Sze, Catarina S. Porto, and C. Yan Cheng

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Cadmium-induced testicular injury, Erica R. Siu, Dolores D. Mruk, Catarina S. Porto, and C. Yan Cheng

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Central modifications of allopregnanolone and β-endorphin following subcutaneous administration of Nestorone, E. Lenzi, N. Pluchino, S. Begliuomini, E. Casarosa, S. Merlini, A. Giannini, M. Luisi, Narender Kumar, Régine Sitruk-Ware, and A.R. Genazzani

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Characterization of a novel gain of function glucocorticoid receptor knock-in mouse, Junhui Zhang, Renshan Ge, Catherine Matte-Martone, Julie Goodwin, Warren D. Shlomchik, Mark J. Mamula, Ali Kooshkabadi, Matthew P. Hardy, and David Geller

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Combined transdermal testosterone gel and the progestin Nestorone suppresses serum gonadotropins in men, Vahid Mahabadi, John K. Amory, Ronald S. Swerdloff, William J. Bremner, Stephanie T. Page, Régine Sitruk-Ware, Peter D. Christensen, Narender Kumar, Yun-yen Tsong, Diana Blithe, and Christina Wang

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Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Coordinating cellular events during spermatogenesis: A biochemical model, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk

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Cytokines and junction restructuring events during spermatogenesis in the testis: An emerging concept of regulation, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Deprival of testicular innervation induces apoptosis of Leydig cells via caspase-8-dependent signaling: A novel survival pathway revealed, Yong-Guang Gong, Yi-Qiu Wang, Min Gu, Ming-Ming Feng, Wei Zhang, and Renshan Ge

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Different cardiovascular effects of progestins according to structure and activity, Anita Nath and Régine Sitruk-Ware

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Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying blood-testis barrier dynamics?, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Distribution, metabolism and excretion of a synthetic androgen 7α-methyl-19-nortestosterone, a potential male-contraceptive, Pramod Vishwanath Prasad, Ramamani Arumugam, Mark Willman, Renshan Ge, Régine Sitruk-Ware, and Narender Kumar

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Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G, Susanna Trapp, Nina Derby, Rachel Singer, Andrew Shaw, Vennansha G. Williams, Stuart G. Turville, Julian W. Bess Jr., Jeffrey D. Lifson, and Melissa Robbiani

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Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier, Linlin Su, C. Yan Cheng, and Dolores D. Mruk

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Effectiveness of medical abortion with mifepristone and buccal misoprostol through 59 gestational days, Mary Fjerstad, Irving Sivin, E. Steve Lichtenberg, James Trussell, Kelly Cleland, and Vanessa Cullins

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Effect of sexual intercourse on the absorption of levonorgestrel after vaginal administration of 0.75 mg in Carraguard® gel: A randomized, cross-over, pharmacokinetic study, Vivian Brache, Horacio B. Croxatto, Narender Kumar, Régine Sitruk-Ware, Leila Cochón, Veronica Schiappacasse, Irving Sivin, Carla Muñoz, Robin A. Maguire, and Anibal Faundes

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Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium, Pearl P.Y. Lie, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Extracellular matrix and its role in spermatogenesis, Michelle K.Y. Siu and C. Yan Cheng

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Focal adhesion kinase is a blood-testis barrier regulator, Erica R. Siu, Elissa W.P. Wong, Dolores D. Mruk, Catarina S. Porto, and C. Yan Cheng

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Increased proliferation but decreased steroidogenic capacity in Leydig cells from mice lacking cyclin-dependent kinase inhibitor 1B, Han Lin, Guo-Xin Hu, Lei Dong, Qiang Dong, Motoko Mukai, Bing-Bing Chen, Denise R. Holsberger, Chantal M. Sottas, Paul S. Cooke, Qing-Quan Lian, Xiao-Kun Li, and Renshan Ge

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In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats, Han Lin, Qing-Quan Lian, Guo-Xin Hu, Yuan Jin, Yunhui Zhang, Dianne O. Hardy, Guo-Rong Chen, Zhong-Qiu Lu, Chantal M. Sottas, Matthew P. Hardy, and Renshan Ge

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Leydig cells: From stem cells to aging, Haolin Chen, Renshan Ge, and Barry R. Zirkin

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Meta-analysis of 200 or 600 mg mifepristone in association with two prostaglandins for termination of early pregnancy, Michel Lièvre and Régine Sitruk-Ware

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Methods for female contraception: A model for innovation in drug delivery systems, Ruth Merkatz, Barbara A. Tokay, and Régine Sitruk-Ware

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Mitogen-activated protein kinases in male reproductive function, Michelle W.M. Li, Dolores D. Mruk, and C. Yan Cheng

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Mono-(2-ethylhexyl) phthalate (MEHP) regulates glucocorticoid metabolism through 11β-hydroxysteroid dehydrogenase 2 in murine gonadotrope cells, Dun Hong, Xing-Wang Li, Qing-Quan Lian, Pankaj Lamba, Daniel J. Bernard, Dianne O. Hardy, Hai-Xiao Chen, and Renshan Ge

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Nitric oxide and cyclic nucleotides: Their roles in junction dynamics and spermatogenesis, Nikki P.Y. Lee and C. Yan Cheng

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Normal responses to restraint stress in mice lacking the gene for neuronal nitric oxide synthase, Ben-Avi Weissman, Chantal M. Sottas, Michael Holmes, Ping Zhou, Costantino Iadecola, Dianne O. Hardy, Renshan Ge, and Matthew P. Hardy

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Novel non-oral hormonal contraceptive methods for women, Anita Nath and Régine Sitruk-Ware

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Parenteral administration of progestins for hormonal replacement therapy, Anita Nath and Régine Sitruk-Ware

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Peptidergic not monoaminergic fibers profusely innervate the young adult human testis, Yong-Guang Gong, Ming-Ming Feng, Xiang-Nong Hu, Yi-Qiu Wang, Min Gu, Wei Zhang, and Renshan Ge

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Pharmacology and clinical applications of selective estrogen receptor modulators, Anita Nath and Régine Sitruk-Ware

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Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence, Guo-Xin Hu, Qing-Quan Lian, Renshan Ge, Dianne O. Hardy, and Xiao-Kun Li

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Phthalate levels and low birth weight: A nested case-control study of Chinese newborns, Yunhui Zhang, Ling Lin, Yang Cao, Bingheng Chen, Lixing Zheng, and Renshan Ge

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Polarity proteins and cell–cell interactions in the testis, Elissa W.P. Wong and C. Yan Cheng

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RAB13 participates in ectoplasmic specialization dynamics in the rat testis, Dolores D. Mruk and Ann S.N. Lau

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Rates of serious infection after changes in regimens for medical abortion, Mary Fjerstad, James Trussell, Irving Sivin, E. Steve Lichtenberg, and Vanessa Cullins

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Regulation of blood-testis barrier dynamics by focal adhesion kinase (FAK): An unexpected turn of events, C. Yan Cheng and Dolores D. Mruk

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Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring, Joseph W. Romano, Bruce Variano, P. Coplan, J. Van Roey, K. Douville, Zeda Rosenberg, Marleen Temmerman, H. Verstraelen, L. Van Bortel, S. Weyers, and M. Mitchnick

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Testicular cell junction: A novel target for male contraception, Nikki P.Y. Lee, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng

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TGF-β3 and TNFα perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: A new concept of BTB regulation during spermatogenesis, Weiliang Xia, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng

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The (+)- and (-)-gossypols potently inhibit human and rat 11β-hydroxysteroid dehydrogenase type 2, Bing-Bing Chen, Han Lin, Guo-Xin Hu, Ying Su, Hong-Yu Zhou, Qing-Quan Lian, Hui Cai, Dianne O. Hardy, Ding-Ying Gu, and Renshan Ge

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Tonsillar application of AT-2 SIV affords partial protection against rectal challenge with SIVmac239, Panagiotis Vagenas; Vennansha G. Williams; Michael Piatak, Jr.; Julian W. Bess; Jeffrey D. Lifson; James Blanchard; Agegnehu Gettie; and Melissa Robbiani

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Transcription regulation in spermatogenesis, Wing-Yee Lui and C. Yan Cheng

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Unexpected heaping in reported gestational age for women undergoing medical abortion, Irving Sivin, James Trussell, E. Steve Lichtenberg, Mary Fjerstad, Kelly Cleland, and Vanessa Cullins

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Value of serum antisperm antibodies in diagnosing obstructive azoospermia, Richard Lee, Marc Goldstein, Brant W. Ullery, Joshua Ehrlich, Marc Soares, Renee A. Razzano, Michael Herman, Mark A. Callahan, Philip S. Li, Peter N. Schlegel, and Steven S. Witkin

Submissions from 2008

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Adult varicocele, Howard H. Kim and Marc Goldstein

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A fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells, Ines Frank, Hella Stössel, Agegnehu Gettie, Stuart G. Turville, Julian W. Bess, Jeffrey D. Lifson, Irving Sivin, Nikolaus Romani, and Melissa Robbiani

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An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis, Helen H.N. Yan, Dolores D. Mruk, Elissa W.P. Wong, Will M. Lee, and C. Yan Cheng

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Anchoring junctions as drug targets: Role in contraceptive development, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng

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A randomized, placebo-controlled trial to assess the safety and acceptability of use of carraguard vaginal gel by heterosexual couples in Thailand, Peter H. Kilmarx, Kelly Blanchard, Supaporn Chaikummao, Barbara Friedland, Nucharee Srivirojana, Cathy Connolly, Paisit Witwatwongwana, Somsak Supawitkul, Philip A. Mock, Thanyanan Chaowanachan, and Jordan W. Tappero

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Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng

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Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Candida albicans-induced DC activation partially restricts HIV amplification in DCs and increases DC to T-cell spread of HIV, Laurence Vachot, Vennansha G. Williams, Julian W. Bess, Jeffrey D. Lifson, and Melissa Robbiani

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CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics, Andreas Schweizer, Peter Rusert, Livia Berlinger, Claudia R. Ruprecht, Axel Mann, Stéphanie Corthesy, Stuart G. Turville, Meropi Aravantinou, Marek Fischer, Melissa Robbiani, Patrick Amstutz, and Alexandra Trkola

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Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion, Xiao-Dong Fu, Maria Silva Giretti, Lorenzo Goglia, Marina Ines Flamini, Angel Matias Sanchez, Chiara Baldacci, Silvia Garibaldi, Régine Sitruk-Ware, Andrea R. Genazzani, and Tommaso Simoncini

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Cross-talk between tight and anchoring junctions: Lesson from the testis, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Cyclic 3′,5′-AMP causes ADAM1/ADAM2 to rapidly diffuse within the plasma membrane of guinea pig sperm, Gary R. Hunnicutt, Dennis E. Koppel, Susanna Kwitny, and Ann E. Cowan

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Delivering non-hormonal contraceptives to men: Advances and obstacles, Dolores D. Mruk and C. Yan Cheng

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Delivery of contraceptives to men: Lesson from other therapeutic drugs, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng