The Population Council’s Center for Biomedical Research (CBR) is a vibrant hub of scientific investigation and product development. Our scientists address critical questions in reproductive health and develop innovative products that protect the health and well-being of millions of people worldwide. CBR is located at Rockefeller University in New York City.

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Submissions from 2020

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Editorial: The 6th International IUD Symposium, David Hubacher, James Sailer, Carolyn Westhoff, and IUD Symposium Organizing Committee

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Endogenously produced LG3/4/5-peptide protects testes against toxicant-induced injury, Linxi Li, Baiping Mao, Siwen Wu, Huitao Li, Lixiu Lv, Renshan Ge, and C. Yan Cheng

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Expanding Access and Instilling Faith in Vaccines, James Sailer

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ICA Foundation supports LNG IUS access in low- and middle-income countries, Population Council

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Microtubule cytoskeleton and spermatogenesis—Lesson from studies of toxicant models, Lingling Wang, Ming Yan, Siwen Wu, Baiping Mao, Chris K.C. Wong, Renshan Ge, Fei Sun, and C. Yan Cheng

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NC1-peptide from collagen α3 (IV) chains in the basement membrane of testes regulates spermatogenesis via p-FAK-Y407, Huitao Li, Shiwen Liu, Siwen Wu, Renshan Ge, and C. Yan Cheng

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NC1‐peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1, Shiwen Liu, Huitao Li, Siwen Wu, Linxi Li, Renshan Ge, and C. Yan Cheng

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No-flip ShangRing circumcision in 10-12 year old boys: Results from randomized clinical trials in Kenya, Omar Al Hussein Alawamlh, Quentin Awori, Mark Barone, Soo-Jeong Kim, Marc Goldstein, Philip S. Li, and Richard K. Lee

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Progesterone vaginal ring as a new contraceptive option for lactating mothers: Evidence from a multicenter non-randomized comparative clinical trial in India, Malabika Roy, Avishek Hazra, Ruth Merkatz, Marlena Gehret Plagianos, Mohcine Alami, L.N. Gaur, Kumudha Aruldas, Heather Sussman, Bruce Variano, and Régine Sitruk-Ware

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Reorganized 3D genome structures support transcriptional regulation in mouse spermatogenesis, Zhengyu Luo, Xiaorong Wang, Hong Jiang, Ruoyu Wang, Jian Chen, Yusheng Chen, Qianlan Xu, Jun Cao, Xiaowen Gong, Ji Wu, Yungui Yang, Wenbo Li, Chunsheng Han, C. Yan Cheng, Michael G. Rosenfeld, Fei Sun, and Xiaoyuan Song

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Role of cell polarity and planar cell polarity (PCP) proteins in spermatogenesis, Linxi Li, Huitao Li, Lingling Wang, Siwen Wu, Lixiu Lv, Anam Tahir, Xiang Xiao, Chris K.C. Wong, Fei Sun, and C. Yan Cheng

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Role of microtubule +TIPs and -TIPs in spermatogenesis—Insights from studies of toxicant models, Baiping Mao, Renshan Ge, and C. Yan Cheng

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Taking the daily grind out of HIV prevention, Thomas Zydowsky

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Testin regulates the blood‐testis barrier via disturbing occludin/ZO‐1 association and actin organization, Linlin Su, Zhaohua Wang, Songtao Xie, Dahai Hu, C. Yan Cheng, Dolores D. Mruk, and Yongjun Guan

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The ins and outs of drug-releasing vaginal rings: A literature review of expulsions and removals, Peter Boyd, Ruth Merkatz, Bruce Variano, and R. Karl Malcolm

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The Population Council's Center for Biomedical Research: A nonprofit product-development entity, Population Council

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Unraveling epigenomic abnormality in azoospermic human males by WGBS, RNA-Seq, and transcriptome profiling analyses, Xiaolong Wu, Chunhai Luo, Longfei Hu, Xue Chen, Yunmei Chen, Jue Fan, C. Yan Cheng, and Fei Sun

Submissions from 2019

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A tat/rev induced limiting dilution assay to measure viral reservoirs in non-human primate models of HIV infection, Ines Frank, Arpan Acharya, Nanda K. Routhu, Meropi Aravantinou, Justin L. Harper, Stephanie Maldonado, Maria Sole Cigoli, Stanka Semova, Svetlana Mazel, Mirko Paiardini, Nina Derby, Siddappa Byrareddy, and Elena Martinelli

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Beyond contraception and hormone replacement therapy: Advancing Nestorone to a neuroprotective drug in the clinic, Julian P. Tuazon, Régine Sitruk-Ware, and Cesario V. Borlongan

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Bleeding profile associated with 1-year use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system: Pooled analysis from phase 3 trials, Carolina Sales Vieira, Ian S. Fraser, Marlena Gehret Plagianos, Anne E. Burke, Carolyn Westhoff, Jeffrey T. Jensen, Vivian Brache, Luis Bahamondes, Ruth Merkatz, Régine Sitruk-Ware, and Diana Blithe

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Bone turnover markers in women participating in a dose-finding trial of a contraceptive vaginal ring releasing Nestorone and estradiol, Molly Tiedeken, Carolyn Westhoff, Adi Cohen, Serge Cremers, Régine Sitruk-Ware, Diana Blithe, and The NICHD Contraceptive Trials Network Vaginal Ring Group

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CAMSAP2 is a microtubule minus-end targeting protein (-TIP) that regulates BTB dynamics through cytoskeletal organization, Baiping Mao, Linxi Li, Renshan Ge, Chao Li, Chris K.C. Wong, Bruno Silvestrini, Qing-Quan Lian, and C. Yan Cheng

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Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization, Wenhui Su and C. Yan Cheng

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Combined Nestorone–testosterone gel suppresses serum gonadotropins to concentrations associated with effective hormonal contraception in men, Bradley D. Anawalt, Mara Y. Roth, Jonas Ceponis, Vijaya Surampadi, John K. Amory, Ronald S. Swerdloff, Peter Y. Liu, Clint Dart, William J. Bremner, Régine Sitruk-Ware, Narender Kumar, Diana Blithe, Stephanie T. Page, and Christina Wang

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Comparative transcriptome analysis of the human endocervix and ectocervix during the proliferative and secretory phases of the menstrual cycle, Sampurna Mukhopadhyay, Y. Liang, H. Hur, Guillermo Villegas, Giulia Calenda, Alexandra Reis, Lily Millen, Patrick Barnable, Lisa Mamkina, Narender Kumar, Tamara Kalir, Rhoda Sperling, and Natalia Teleshova

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Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques, Giulia Calenda, Ines Frank, Geraldine Arrode-Bruses, Amarendra Pegu, Keyun Wang, James Arthos, Claudia Cicala, Kenneth A. Rogers, Lisa Shirreff, Brooke Grasperge, James L. Blanchard, Stephanie Maldonado, Kevin Roberts, Agegnehu Gettie, Francois Villinger, Anthony S. Fauci, John R. Mascola, and Elena Martinelli

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Efficacy and safety of a 1-year segesterone acetate and ethinyl estradiol contraceptive vaginal system, Ruth Merkatz, Maureen Magnani, Heather Sussman, George W. Creasy, and Régine Sitruk-Ware

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Efficacy of the 1-year (13-cycle) segesterone acetate and ethinylestradiol contraceptive vaginal system: Results of two multicentre, open-label, single-arm, phase 3 trials, David F. Archer, Ruth Merkatz, Luis Bahamondes, Carolyn Westhoff, Philip Darney, Dan Apter, Jeffrey T. Jensen, Vivian Brache, Anita L. Nelson, Erika Banks, György Bártfai, David J. Portman, Marlena Gehret Plagianos, Clint Dart, Narender Kumar, George W. Creasy, Régine Sitruk-Ware, and Diana Blithe

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Emerging role for SRC family kinases in junction dynamics during spermatogenesis, Xiang Xiao, Yue Yang, Baiping Mao, C. Yan Cheng, and Ya Ni

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F5-peptide and mTORC1/rpS6 effectively enhance BTB transport function in the testis—Lesson from the adjudin model, Baiping Mao, Linxi Li, Ming Yan, Chris K.C. Wong, Bruno Silvestrini, Chao Li, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng

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F5-peptide enhances the efficacy of the non-hormonal male contraceptive adjudin, Haiqi Chen, Dolores D. Mruk, Chris K.C. Wong, Bruno Silvestrini, and C. Yan Cheng

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In vitro release testing methods for drug-releasing vaginal rings, Peter Boyd, Bruce Variano, Patrick Spence, Clare F. McCoy, Diarmaid J. Murphy, Yahya H. Dallal Bashi, and R. Karl Malcolm

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Kruppel-like factor 6 regulates Sertoli cell blood-testis barrier, Xiu-Xia Wang, Yan Zhang, Xiao-Yu Li, Jian Li, Ji-Xin Tang, Yuan-Yuan Li, Shou-Long Deng, C. Yan Cheng, and Yi-Xun Liu

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mTORC1/rpS6 and spermatogenic function in the testis—Insights from the adjudin model, Siwen Wu, Ming Yan, Linxi Li, Baiping Mao, Chris K.C. Wong, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng

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mTORC1/rpS6 signaling complex that modifies BTB transport function—An in vivo study using the adjudin model, Ming Yan, Linxi Li, Baiping Mao, Huitao Li, Stephen Y.T. Li, Dolores D. Mruk, Bruno Silvestrini, Qing-Quan Lian, Renshan Ge, and C. Yan Cheng

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Mucosal susceptibility to human immunodeficiency virus infection in the proliferative and secretory phases of the menstrual cycle, Giulia Calenda, Guillermo Villegas, Alexandra Reis, Lily Millen, Patrick Barnable, Lisa Mamkina, Narender Kumar, Kevin Roberts, Tamara Kalir, Elena Martinelli, Rhoda Sperling, and Natalia Teleshova

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Myosin VIIa supports spermatid/organelle transport and cell adhesion during spermatogenesis in the rat testis, Qing Wen, Siwen Wu, Will M. Lee, Chris K.C. Wong, Wing-Yee Lui, Bruno Silvestrini, and C. Yan Cheng

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Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization, Linxi Li, Baiping Mao, Ming Yan, Siwen Wu, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng

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Post-use ring weight and residual drug content as potential objective measures of user adherence to a contraceptive progesterone vaginal ring, Diarmaid J. Murphy, Clare F. McCoy, Marlena Gehret Plagianos, Saumya RamaRao, Ruth Merkatz, Heather Clark, Peter Boyd, Bruce Variano, and R. Karl Malcolm

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Preventing secondary exposure to women from men applying a novel Nestorone/testosterone contraceptive gel, F. Yuen, S. Wu, A. Thirumalai, Ronald S. Swerdloff, Stephanie T. Page, Peter Y. Liu, Clint Dart, H. Wu, Diana Blithe, Régine Sitruk-Ware, J. Long, F. Bai, L. Hull, William J. Bremner, Bradley D. Anawalt, and Christina Wang

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Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro study, Linxi Li, Siwen Wu, Ming Yan, Qing-Quan Lian, Renshan Ge, and C. Yan Cheng

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Regulation of BTB dynamics in spermatogenesis—Insights from the adjudin model, Baiping Mao, Linxi Li, Ming Yan, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng

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Rollout of ShangRing circumcision with active surveillance for adverse events and monitoring for uptake in Kenya, Elijah Odoyo-June, Nandi Owuor, Saida Kassim, Stephanie Davis, Kawango Agot, Kennedy Serrem, George Otieno, Quentin Awori, Jonas Hines, Carlos Toledo, Catey Laube, Christine Kisia, Appolonia Aoko, Vincent Ojiambo, Zebedee Mwandi, Ambrose Juma, and Bartilol Kigen

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Segesterone acetate/ethinyl estradiol 12-month contraceptive vaginal system safety evaluation, Kristina Gemzell-Danielsson, Régine Sitruk-Ware, Mitchell Creinin, Michael Thomas, Kurt T. Barnhart, George W. Creasy, Heather Sussman, Mohcine Alami, Anne E. Burke, Edith Weisberg, Ian S. Fraser, Marie-José Miranda, Melissa Gilliam, James Liu, Bruce R. Carr, Marlena Gehret Plagianos, Kevin Roberts, and Diana Blithe

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Topical formulations to prevent sexually transmitted infections: Are we on track?, José Fernández-Romero, Maria Gabriela Paglini, and Thomas Zydowsky

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Use of topical versus injectable anaesthesia for ShangRing circumcisions in men and boys in Kenya: Results from a randomized controlled trial, Quentin Awori, Philip S. Li, Richard K. Lee, Daniel Ouma, Millicent Oundo, Mukhaye Barasa, Nereah Obura, David Mwamkita, Raymond Otieno Simba, Jairus Oketch, Nixon Nyangweso, Mary N. Maina, Nicholas Kiswi, Michael Kirui, Betty Chirchir, Marc Goldstein, and Mark Barone

Submissions from 2018

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Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis, Qing Wen, Nan Li, Xiang Xiao, Wing-Yee Lui, Darren S. Chu, Chris K.C. Wong, Qing-Quan Lian, Renshan Ge, Will M. Lee, Bruno Silvestrini, and C. Yan Cheng

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Advances in our understanding of human spermatogenesis, Qing Wen, Elizabeth I. Tang, Tito T. Jesus, Bruno Silvestrini, and C. Yan Cheng

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A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis, Shun Bai, Le Cheng, Yingwen Zhang, Chunsen Zhu, Zhiping Zhu, Ruping Zhu, C. Yan Cheng, Lan Ye, and Ke Zheng

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A look into the testis as a reservoir for HIV and ZIKV—A reproductive biologist’s perspective, Elizabeth I. Tang, Christopher L. Robinson, Chi Nok Chong, Shuibing Chen, and C. Yan Cheng

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Cell junctions in the testis as targets for toxicants, Elissa W.P. Wong, Helen H.N. Yan, Michelle W.M. Li, Pearl P.Y. Lie, Dolores D. Mruk, and C. Yan Cheng

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Cell polarity and cytoskeletons—Lesson from the testis, Qing Wen, Dolores D. Mruk, Elizabeth I. Tang, Chris K.C. Wong, Wing-Yee Lui, Will M. Lee, Xiang Xiao, Bruno Silvestrini, and C. Yan Cheng

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Cell polarity and planar cell polarity (PCP) in spermatogenesis, Haiqi Chen, Dolores D. Mruk, Wing-Yee Lui, Chris K.C. Wong, Will M. Lee, and C. Yan Cheng

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Characterization of molecular changes in endometrium associated with chronic use of progesterone receptor modulators: Ulipristal acetate versus mifepristone, Athilakshmi Kannan, A. Bhurke, Régine Sitruk-Ware, P.G. Lalitkumar, Kristina Gemzell-Danielsson, A. Williams, R.N. Taylor, Milan K. Bagchi, and Indrani C. Bagchi

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Continuous dosing of a novel contraceptive vaginal ring releasing Nestorone® and estradiol: Pharmacokinetics from a dose-finding study, Jeffrey T. Jensen, Alison E. Edelman, Beatrice A. Chen, D.F. Archer, Kurt T. Barnhart, M.A. Thomas, Anne E. Burke, Carolyn Westhoff, Livia Wan, Régine Sitruk-Ware, Narender Kumar, Bruce Variano, and Diana Blithe

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Development of a vaginal fast-dissolving insert combining griffithsin and carrageenan for potential use against sexually transmitted infections, Manjari Lal, Manshun Lai, Shweta Ugaonkar, Asa Wesenberg, Larisa Kizima, Aixa Rodriguez, Keith Levendosky, Olga Mizenina, José Fernández-Romero, and Thomas Zydowsky

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Effects of concurrent vaginal miconazole treatment on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol delivered from a contraceptive vaginal ring: A randomized, crossover drug–drug interaction study, Katharine B. Simmons, Narender Kumar, Marlena Gehret Plagianos, Kevin Roberts, Elena Hoskin, Leo Han, Mohcine Alami, George W. Creasy, Bruce Variano, and Ruth Merkatz

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Factors associated with non-adherence to instructions for using the Nestorone®/ethinyl estradiol contraceptive vaginal ring, Bianca M. Stifani, Marlena Gehret Plagianos, Carolina Sales Vieira, and Ruth Merkatz

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Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo, Nina Derby, Manjari Lal, Meropi Aravantinou, Larisa Kizima, Patrick Barnable, Aixa Rodriguez, Manshun Lai, Asa Wesenberg, Shweta Ugaonkar, Keith Levendosky, Olga Mizenina, Kyle Kleinbeck, Jeffrey D. Lifson, M. Melissa Peet, Zachary Lloyd, Michael Benson, Walid Heneine, Barry R. O'Keefe, Melissa Robbiani, Elena Martinelli, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Natalia Teleshova, José Fernández-Romero, and Thomas Zydowsky

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Integrin α_4β_7 blockade preferentially impacts CCR6^+ lymphocyte subsets in blood and mucosal tissues of naive rhesus macaques, Giulia Calenda, Rassamon Keawvichit, Geraldine Arrode-Bruses, Kovit Pattanapanyasat, Ines Frank, Siddappa Byrareddy, James Arthos, Claudia Cicala, Brooke Grasperge, James L. Blanchard, Agegnehu Gettie, Keith A. Reimann, Aftab A. Ansari, and Elena Martinelli

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MAdCAM costimulation through Integrin-α_4β_7 promotes HIV replication, Fatima Nawaz, Livia R. Goes, Jocelyn C. Ray, Ronke Olowojesiku, Alia Sajani, Aftab A. Ansari, Ian Perrone, Joseph Hiatt, Donald Van Ryk, Danlan Wei, Mia Waliszewski, Marcelo A. Soares, Katija Jelicic, Mark Connors, Stephen A. Migueles, Elena Martinelli, Francois Villinger, Claudia Cicala, Anthony S. Fauci, and James Arthos

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Male germ cells support long-term propagation of Zika virus, Christopher L. Robinson, Angie C.N. Chong, Alison W. Ashbrook, Ginnie Jeng, Julia Jin, Haiqi Chen, Elizabeth I. Tang, Laura A. Martin, Rosa S. Kim, Reyn M. Kenyon, Eileen Do, Joseph M. Luna, Mohsan Saeed, Lori Zeltser, Harold Ralph, Vanessa L. Dudley, Marc Goldstein, Charles M. Rice, C. Yan Cheng, Marco Seandel, and Shuibing Chen

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Mechanistic insights into PFOS-mediated Sertoli cell injury, Baiping Mao, Dolores D. Mruk, Qing-Quan Lian, Renshan Ge, Chao Li, Bruno Silvestrini, and C. Yan Cheng

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Melatonin promotes sheep Leydig cell testosterone secretion in a co-culture with Sertoli cells, Shou-Long Deng, Zhi-Peng Wang, Cheng Jin, Xiao-Long Kang, Alia Batool, Yan Zhang, Xiao-Yu Li, Xiu-Xia Wang, Su-Ren Chen, Chawn-Shang Chang, C. Yan Cheng, Zheng-Xing Lian, and Yi-Xun Liu

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Monitoring the integrity of the blood-testis barrier (BTB): An in vivo assay, Haiqi Chen, Wing-Yee Lui, Dolores D. Mruk, Xiang Xiao, Renshan Ge, Qing-Quan Lian, Will M. Lee, Bruno Silvestrini, and C. Yan Cheng

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mTORC1/rpS6 regulates blood-testis barrier (BTB) dynamics and spermatogenetic function in the testis in vivo, Stephen Y.T. Li, Ming Yan, Haiqi Chen, Tito T. Jesus, Will M. Lee, Xiang Xiao, and C. Yan Cheng

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Neurosteroidogenesis and progesterone anti-inflammatory/neuroprotective effects, Alejandro De Nicola, Laura Garay, Maria Meyer, Rachida Guennoun, Régine Sitruk-Ware, Michael Schumacher, and Maria Claudia Gonzalez Deniselle

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Non-clinical studies of progesterone, Régine Sitruk-Ware

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Patent: Combination product for the prevention of sexually transmitted infections, Barry R. O'Keefe, Melissa Robbiani, and José Fernández-Romero

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Patent: Neuroprotection and myelin repair using Nestorone.RTM, Régine Sitruk-Ware, Michael Schumacher, Maria Helmut, Roberta Brinton, Martine El-Etr, Abdelmouman Ghoumari, and Rachida Guennoun

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Regulation of blood–testis barrier assembly in vivo by germ cells, Xiao-Yu Li, Yan Zhang, Xiu-Xia Wang, Cheng Jin, Yu-Qian Wang, Tie-Cheng Sun, Ji-Xin Tang, Alia Batool, Shou-Long Deng, Su-Ren Chen, C. Yan Cheng, and Yi-Xun Liu

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Regulation of blood-testis barrier (BTB) dynamics, role of actin-, and microtubule-based cytoskeletons, Qing Wen, Elizabeth I. Tang, Nan Li, Dolores D. Mruk, Will M. Lee, Bruno Silvestrini, and C. Yan Cheng

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Safety of tubal occlusion by minilaparotomy provided by trained clinical officers versus assistant medical officers in Tanzania: A randomized, controlled, noninferiority trial, Mark Barone, Zuhura Mbuguni, Japhet Ominde Achola, Annette Almeida, Carmela Cordero, Joseph Kanama, Adriana Marquina, Projestine Muganyizi, Jamilla Mwanga, Daniel Ouma, Caitlin S. Shannon, and Leopold Tibyehabwa

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Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7, Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa Byrareddy, Philip J. Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D. Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A. Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S. Fauci, and James Arthos

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Signaling pathways regulating blood-tissue barriers—Lesson from the testis, Qing Wen, Elizabeth I. Tang, Ying Gao, Tito T. Jesus, Darren S. Chu, Will M. Lee, Chris K.C. Wong, Yi-Xun Liu, Xiang Xiao, Bruno Silvestrini, and C. Yan Cheng

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Simplifying the ShangRing technique for circumcision in boys and men: Use of the no-flip technique with randomization to removal at 7 days versus spontaneous detachment, Mark Barone, Philip S. Li, Richard K. Lee, Daniel Ouma, Millicent Oundo, Mukhaye Barasa, Jairus Oketch, Patrick Otiende, Nixon Nyangweso, Mary N. Maina, Nicholas Kiswi, Betty Chirchir, Marc Goldstein, and Quentin Awori

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Solid state ^13C NMR spectroscopy provides direct evidence for reaction between ethinyl estradiol and a silicone elastomer vaginal ring drug delivery system, Clare F. McCoy, David C. Apperley, Bruce Variano, Heather Sussman, Dan Loeven, Peter Boyd, and R. Karl Malcolm

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Study to evaluate the safety of griffithsin in a carrageenan gel in healthy women, Population Council

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SUMOylation regulates germinal vesicle break-down and the AKT/PKB pathway during mouse oocyte maturation, Weber Beringui Feitosa and Patricia L. Morris

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Therapeutic progestin segesterone acetate promotes neurogenesis: Implications for sustaining regeneration in female brain, Shuhua Chen, Narender Kumar, Zisu Mao, Régine Sitruk-Ware, and Roberta Diaz Brinton

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Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: Updated indirect comparison meta-analysis, Agustin Conde-Agudelo, Roberto Romero, Eduardo Da Fonseca, John M. O'Brien, Elcin Cetingoz, George W. Creasy, Sonia S. Hassan, Offer Erez, Percy Pacora, and Kypros H. Nicolaides

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Vangl2 regulates spermatid planar cell polarity through microtubule (MT)-based cytoskeleton in the rat testis, Haiqi Chen, Xiang Xiao, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng

Submissions from 2017

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Abcb1a and Abcb1b genes function differentially in blood–testis barrier dynamics in the rat, Linlin Su, C. Yan Cheng, Will M. Lee, Min Zhang, Fangfang Yang, Bin Zhao, Daishu Han, Yixun Liu, and Dahai Hu

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Adjudin—A male contraceptive with anti-cancer, anti-neuroinflammation and anti-ototoxicity activities, Yan Ho Cheng, Weiliang Xia, Xiang Xiao, Elizabeth I. Tang, Haiqi Chen, Qing Wen, Ying Gao, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng

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A fresh look at an old problem, Thomas Zydowsky

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A model of genital herpes simplex virus Type 1 infection in Rhesus Macaques, Meropi Aravantinou, Ines Frank, Geraldine Arrode-Bruses, Moriah Szpara, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Nina Derby, and Elena Martinelli

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An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques, Nina Derby, Meropi Aravantinou, Jessica Kenney, Shweta Ugaonkar, Asa Wesenberg, Jolanta Wilk, Larisa Kizima, Aixa Rodriguez, Shimin Zhang, Olga Mizenina, Keith Levendosky, Michael Cooney, Samantha Seidor, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, José Fernández-Romero, Thomas Zydowsky, and Melissa Robbiani

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Annexin A2 is critical for blood-testis barrier integrity and spermatid disengagement in the mammalian testis, Katarzyna Chojnacka, Barbara Bilinska, and Dolores D. Mruk

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Basement membrane laminin α2 regulates BTB dynamics via its effects on F-actin- and microtubule (MT)-cytoskeletons via mTORC1 signaling, Ying Gao, Haiqi Chen, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng

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Cell polarity, cell adhesion, and spermatogenesis: Role of cytoskeletons, Linxi Li, Ying Gao, Haiqi Chen, Tito T. Jesus, Elizabeth I. Tang, Nan Li, Qing-Quan Lian, Renshan Ge, and C. Yan Cheng

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Drebrin and spermatogenesis, Haiqi Chen, Michelle W.M. Li, and C. Yan Cheng

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Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance, Kenneth S.K. Tung, Jessica Harakal, Hui Qiao, Claudia Rival, Jonathan C.H. Li, Alberta G.A. Paul, Karen Wheeler, Patcharin Pramoonjago, Constance M. Grafer, Wei Sun, Robert D. Sampson, Elissa W.P. Wong, Prabhakara P. Reddi, Umesh S. Deshmukh, Daniel M. Hardy, Huanghui Tang, C. Yan Cheng, and Erwin Goldberg

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Emerging role for mammalian target of rapamycin in male fertility, Pedro F. Oliveira, C. Yan Cheng, and Marco G. Alves

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Experimental oral herpes simplex virus-1 (HSV-1) co-infection in simian immunodeficiency virus (SIV)-infected rhesus macaques, Meropi Aravantinou, Olga Mizenina, Giulia Calenda, Jessica Kenney, Ines Frank, Jeffrey D. Lifson, Moriah Szpara, Lichen Jing, David M. Koelle, Natalia Teleshova, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Elena Martinelli, and Nina Derby

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Factors predicting improper use of a woman-controlled long-acting reversible contraceptive: Results from the acceptability study of a novel contraceptive vaginal ring, Bianca M. Stifani, Marlena Gehret Plagianos, Carolina Sales Vieira, and Ruth Merkatz

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Focal adhesion kinase (FAK), Haiqi Chen and C. Yan Cheng

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Human spermatogenesis and its regulation, Haiqi Chen, Dolores D. Mruk, Xiang Xiao, and C. Yan Cheng

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Impact of various progestins with or without transdermal testosterone on gonadotropin levels for non-invasive hormonal male contraception: A randomized clinical trial, Michael Zitzmann, Julia Rohayem, J. Raidt, Sabine Kliesch, Narender Kumar, and Régine Sitruk-Ware

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Lonidamine-ethyl ester-mediated remodelling of the Sertoli cell cytoskeleton induces phosphorylation of plakoglobin and promotes its interaction with α-catenin at the blood–testis barrier, Dolores D. Mruk, Michele Bonanomi, and Bruno Silvestrini

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Mammalian target of rapamycin (mTOR): A central regulator of male fertility?, Tito T. Jesus, Pedro F. Oliveira, Mario Sousa, C. Yan Cheng, and Marco G. Alves