Submissions from 2019
Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques, Giulia Calenda, Ines Frank, Geraldine Arrode-Bruses, Amarendra Pegu, Keyun Wang, James Arthos, Claudia Cicala, Kenneth A. Rogers, Lisa Shirreff, Brooke Grasperge, James L. Blanchard, Stephanie Maldonado, Kevin Roberts, Agegnehu Gettie, Francois Villinger, Anthony S. Fauci, John R. Mascola, and Elena Martinelli
Efficacy and safety of a 1-year segesterone acetate and ethinyl estradiol contraceptive vaginal system, Ruth Merkatz, Maureen Magnani, Heather Sussman, George W. Creasy, and Régine Sitruk-Ware
Efficacy of the 1-year (13-cycle) segesterone acetate and ethinylestradiol contraceptive vaginal system: Results of two multicentre, open-label, single-arm, phase 3 trials, David F. Archer, Ruth Merkatz, Luis Bahamondes, Carolyn Westhoff, Philip Darney, Dan Apter, Jeffrey T. Jensen, Vivian Brache, Anita L. Nelson, Erika Banks, György Bártfai, David J. Portman, Marlena Gehret Plagianos, Clint Dart, Narender Kumar, George W. Creasy, Régine Sitruk-Ware, and Diana Blithe
Emerging role for SRC family kinases in junction dynamics during spermatogenesis, Xiang Xiao, Yue Yang, Baiping Mao, C. Yan Cheng, and Ya Ni
F5-peptide and mTORC1/rpS6 effectively enhance BTB transport function in the testis—Lesson from the adjudin model, Baiping Mao, Linxi Li, Ming Yan, Chris K.C. Wong, Bruno Silvestrini, Chao Li, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng
F5-peptide enhances the efficacy of the non-hormonal male contraceptive adjudin, Haiqi Chen, Dolores D. Mruk, Chris K.C. Wong, Bruno Silvestrini, and C. Yan Cheng
In vitro release testing methods for drug-releasing vaginal rings, Peter Boyd, Bruce Variano, Patrick Spence, Clare F. McCoy, Diarmaid J. Murphy, Yahya H. Dallal Bashi, and R. Karl Malcolm
Kruppel-like factor 6 regulates Sertoli cell blood-testis barrier, Xiu-Xia Wang, Yan Zhang, Xiao-Yu Li, Jian Li, Ji-Xin Tang, Yuan-Yuan Li, Shou-Long Deng, C. Yan Cheng, and Yi-Xun Liu
mTORC1/rpS6 and spermatogenic function in the testis—Insights from the adjudin model, Siwen Wu, Ming Yan, Linxi Li, Baiping Mao, Chris K.C. Wong, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng
mTORC1/rpS6 signaling complex that modifies BTB transport function—An in vivo study using the adjudin model, Ming Yan, Linxi Li, Baiping Mao, Huitao Li, Stephen Y.T. Li, Dolores D. Mruk, Bruno Silvestrini, Qing-Quan Lian, Renshan Ge, and C. Yan Cheng
Mucosal susceptibility to human immunodeficiency virus infection in the proliferative and secretory phases of the menstrual cycle, Giulia Calenda, Guillermo Villegas, Alexandra Reis, Lily Millen, Patrick Barnable, Lisa Mamkina, Narender Kumar, Kevin Roberts, Tamara Kalir, Elena Martinelli, Rhoda Sperling, and Natalia Teleshova
Myosin VIIa supports spermatid/organelle transport and cell adhesion during spermatogenesis in the rat testis, Qing Wen, Siwen Wu, Will M. Lee, Chris K.C. Wong, Wing-Yee Lui, Bruno Silvestrini, and C. Yan Cheng
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization, Linxi Li, Baiping Mao, Ming Yan, Siwen Wu, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng
Post-use ring weight and residual drug content as potential objective measures of user adherence to a contraceptive progesterone vaginal ring, Diarmaid J. Murphy, Clare F. McCoy, Marlena Gehret Plagianos, Saumya RamaRao, Ruth Merkatz, Heather Clark, Peter Boyd, Bruce Variano, and R. Karl Malcolm
Preventing secondary exposure to women from men applying a novel Nestorone/testosterone contraceptive gel, F. Yuen, S. Wu, A. Thirumalai, Ronald S. Swerdloff, Stephanie T. Page, Peter Y. Liu, Clint Dart, H. Wu, Diana Blithe, Régine Sitruk-Ware, J. Long, F. Bai, L. Hull, William J. Bremner, Bradley D. Anawalt, and Christina Wang
Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro study, Linxi Li, Siwen Wu, Ming Yan, Qing-Quan Lian, Renshan Ge, and C. Yan Cheng
Regulation of BTB dynamics in spermatogenesis—Insights from the adjudin model, Baiping Mao, Linxi Li, Ming Yan, Renshan Ge, Qing-Quan Lian, and C. Yan Cheng
Rollout of ShangRing circumcision with active surveillance for adverse events and monitoring for uptake in Kenya, Elijah Odoyo-June, Nandi Owuor, Saida Kassim, Stephanie Davis, Kawango Agot, Kennedy Serrem, George Otieno, Quentin Awori, Jonas Hines, Carlos Toledo, Catey Laube, Christine Kisia, Appolonia Aoko, Vincent Ojiambo, Zebedee Mwandi, Ambrose Juma, and Bartilol Kigen
Segesterone acetate/ethinyl estradiol 12-month contraceptive vaginal system safety evaluation, Kristina Gemzell-Danielsson, Régine Sitruk-Ware, Mitchell Creinin, Michael Thomas, Kurt T. Barnhart, George W. Creasy, Heather Sussman, Mohcine Alami, Anne E. Burke, Edith Weisberg, Ian S. Fraser, Marie-José Miranda, Melissa Gilliam, James Liu, Bruce R. Carr, Marlena Gehret Plagianos, Kevin Roberts, and Diana Blithe
Topical formulations to prevent sexually transmitted infections: Are we on track?, José Fernández-Romero, Maria Gabriela Paglini, and Thomas Zydowsky
Use of topical versus injectable anaesthesia for ShangRing circumcisions in men and boys in Kenya: Results from a randomized controlled trial, Quentin Awori, Philip S. Li, Richard K. Lee, Daniel Ouma, Millicent Oundo, Mukhaye Barasa, Nereah Obura, David Mwamkita, Raymond Otieno Simba, Jairus Oketch, Nixon Nyangweso, Mary N. Maina, Nicholas Kiswi, Michael Kirui, Betty Chirchir, Marc Goldstein, and Mark Barone
Submissions from 2018
Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis, Qing Wen, Nan Li, Xiang Xiao, Wing-Yee Lui, Darren S. Chu, Chris K.C. Wong, Qing-Quan Lian, Renshan Ge, Will M. Lee, Bruno Silvestrini, and C. Yan Cheng
Advances in our understanding of human spermatogenesis, Qing Wen, Elizabeth I. Tang, Tito T. Jesus, Bruno Silvestrini, and C. Yan Cheng
A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis, Shun Bai, Le Cheng, Yingwen Zhang, Chunsen Zhu, Zhiping Zhu, Ruping Zhu, C. Yan Cheng, Lan Ye, and Ke Zheng
A look into the testis as a reservoir for HIV and ZIKV—A reproductive biologist’s perspective, Elizabeth I. Tang, Christopher L. Robinson, Chi Nok Chong, Shuibing Chen, and C. Yan Cheng
Cell junctions in the testis as targets for toxicants, Elissa W.P. Wong, Helen H.N. Yan, Michelle W.M. Li, Pearl P.Y. Lie, Dolores D. Mruk, and C. Yan Cheng
Cell polarity and cytoskeletons—Lesson from the testis, Qing Wen, Dolores D. Mruk, Elizabeth I. Tang, Chris K.C. Wong, Wing-Yee Lui, Will M. Lee, Xiang Xiao, Bruno Silvestrini, and C. Yan Cheng
Cell polarity and planar cell polarity (PCP) in spermatogenesis, Haiqi Chen, Dolores D. Mruk, Wing-Yee Lui, Chris K.C. Wong, Will M. Lee, and C. Yan Cheng
Characterization of molecular changes in endometrium associated with chronic use of progesterone receptor modulators: Ulipristal acetate versus mifepristone, Athilakshmi Kannan, A. Bhurke, Régine Sitruk-Ware, P.G. Lalitkumar, Kristina Gemzell-Danielsson, A. Williams, R.N. Taylor, Milan K. Bagchi, and Indrani C. Bagchi
Continuous dosing of a novel contraceptive vaginal ring releasing Nestorone® and estradiol: Pharmacokinetics from a dose-finding study, Jeffrey T. Jensen, Alison E. Edelman, Beatrice A. Chen, D.F. Archer, Kurt T. Barnhart, M.A. Thomas, Anne E. Burke, Carolyn Westhoff, Livia Wan, Régine Sitruk-Ware, Narender Kumar, Bruce Variano, and Diana Blithe
Development of a vaginal fast-dissolving insert combining griffithsin and carrageenan for potential use against sexually transmitted infections, Manjari Lal, Manshun Lai, Shweta Ugaonkar, Asa Wesenberg, Larisa Kizima, Aixa Rodriguez, Keith Levendosky, Olga Mizenina, José Fernández-Romero, and Thomas Zydowsky
Effects of concurrent vaginal miconazole treatment on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol delivered from a contraceptive vaginal ring: A randomized, crossover drug–drug interaction study, Katharine B. Simmons, Narender Kumar, Marlena Gehret Plagianos, Kevin Roberts, Elena Hoskin, Leo Han, Mohcine Alami, George W. Creasy, Bruce Variano, and Ruth Merkatz
Factors associated with non-adherence to instructions for using the Nestorone®/ethinyl estradiol contraceptive vaginal ring, Bianca M. Stifani, Marlena Gehret Plagianos, Carolina Sales Vieira, and Ruth Merkatz
Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo, Nina Derby, Manjari Lal, Meropi Aravantinou, Larisa Kizima, Patrick Barnable, Aixa Rodriguez, Manshun Lai, Asa Wesenberg, Shweta Ugaonkar, Keith Levendosky, Olga Mizenina, Kyle Kleinbeck, Jeffrey D. Lifson, M. Melissa Peet, Zachary Lloyd, Michael Benson, Walid Heneine, Barry R. O'Keefe, Melissa Robbiani, Elena Martinelli, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Natalia Teleshova, José Fernández-Romero, and Thomas Zydowsky
Integrin α_4β_7 blockade preferentially impacts CCR6^+ lymphocyte subsets in blood and mucosal tissues of naive rhesus macaques, Giulia Calenda, Rassamon Keawvichit, Geraldine Arrode-Bruses, Kovit Pattanapanyasat, Ines Frank, Siddappa Byrareddy, James Arthos, Claudia Cicala, Brooke Grasperge, James L. Blanchard, Agegnehu Gettie, Keith A. Reimann, Aftab A. Ansari, and Elena Martinelli
MAdCAM costimulation through Integrin-α_4β_7 promotes HIV replication, Fatima Nawaz, Livia R. Goes, Jocelyn C. Ray, Ronke Olowojesiku, Alia Sajani, Aftab A. Ansari, Ian Perrone, Joseph Hiatt, Donald Van Ryk, Danlan Wei, Mia Waliszewski, Marcelo A. Soares, Katija Jelicic, Mark Connors, Stephen A. Migueles, Elena Martinelli, Francois Villinger, Claudia Cicala, Anthony S. Fauci, and James Arthos
Male germ cells support long-term propagation of Zika virus, Christopher L. Robinson, Angie C.N. Chong, Alison W. Ashbrook, Ginnie Jeng, Julia Jin, Haiqi Chen, Elizabeth I. Tang, Laura A. Martin, Rosa S. Kim, Reyn M. Kenyon, Eileen Do, Joseph M. Luna, Mohsan Saeed, Lori Zeltser, Harold Ralph, Vanessa L. Dudley, Marc Goldstein, Charles M. Rice, C. Yan Cheng, Marco Seandel, and Shuibing Chen
Mechanistic insights into PFOS-mediated Sertoli cell injury, Baiping Mao, Dolores D. Mruk, Qing-Quan Lian, Renshan Ge, Chao Li, Bruno Silvestrini, and C. Yan Cheng
Melatonin promotes sheep Leydig cell testosterone secretion in a co-culture with Sertoli cells, Shou-Long Deng, Zhi-Peng Wang, Cheng Jin, Xiao-Long Kang, Alia Batool, Yan Zhang, Xiao-Yu Li, Xiu-Xia Wang, Su-Ren Chen, Chawn-Shang Chang, C. Yan Cheng, Zheng-Xing Lian, and Yi-Xun Liu
Monitoring the integrity of the blood-testis barrier (BTB): An in vivo assay, Haiqi Chen, Wing-Yee Lui, Dolores D. Mruk, Xiang Xiao, Renshan Ge, Qing-Quan Lian, Will M. Lee, Bruno Silvestrini, and C. Yan Cheng
mTORC1/rpS6 regulates blood-testis barrier (BTB) dynamics and spermatogenetic function in the testis in vivo, Stephen Y.T. Li, Ming Yan, Haiqi Chen, Tito T. Jesus, Will M. Lee, Xiang Xiao, and C. Yan Cheng
Neurosteroidogenesis and progesterone anti-inflammatory/neuroprotective effects, Alejandro De Nicola, Laura Garay, Maria Meyer, Rachida Guennoun, Régine Sitruk-Ware, Michael Schumacher, and Maria Claudia Gonzalez Deniselle
Non-clinical studies of progesterone, Régine Sitruk-Ware
Patent: Combination product for the prevention of sexually transmitted infections, Barry R. O'Keefe, Melissa Robbiani, and José Fernández-Romero
Patent: Neuroprotection and myelin repair using Nestorone.RTM, Régine Sitruk-Ware, Michael Schumacher, Maria Helmut, Roberta Brinton, Martine El-Etr, Abdelmouman Ghoumari, and Rachida Guennoun
Regulation of blood–testis barrier assembly in vivo by germ cells, Xiao-Yu Li, Yan Zhang, Xiu-Xia Wang, Cheng Jin, Yu-Qian Wang, Tie-Cheng Sun, Ji-Xin Tang, Alia Batool, Shou-Long Deng, Su-Ren Chen, C. Yan Cheng, and Yi-Xun Liu
Regulation of blood-testis barrier (BTB) dynamics, role of actin-, and microtubule-based cytoskeletons, Qing Wen, Elizabeth I. Tang, Nan Li, Dolores D. Mruk, Will M. Lee, Bruno Silvestrini, and C. Yan Cheng
Safety of tubal occlusion by minilaparotomy provided by trained clinical officers versus assistant medical officers in Tanzania: A randomized, controlled, noninferiority trial, Mark Barone, Zuhura Mbuguni, Japhet Ominde Achola, Annette Almeida, Carmela Cordero, Joseph Kanama, Adriana Marquina, Projestine Muganyizi, Jamilla Mwanga, Daniel Ouma, Caitlin S. Shannon, and Leopold Tibyehabwa
Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7, Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa Byrareddy, Philip J. Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D. Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A. Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S. Fauci, and James Arthos
Signaling pathways regulating blood-tissue barriers—Lesson from the testis, Qing Wen, Elizabeth I. Tang, Ying Gao, Tito T. Jesus, Darren S. Chu, Will M. Lee, Chris K.C. Wong, Yi-Xun Liu, Xiang Xiao, Bruno Silvestrini, and C. Yan Cheng
Simplifying the ShangRing technique for circumcision in boys and men: Use of the no-flip technique with randomization to removal at 7 days versus spontaneous detachment, Mark Barone, Philip S. Li, Richard K. Lee, Daniel Ouma, Millicent Oundo, Mukhaye Barasa, Jairus Oketch, Patrick Otiende, Nixon Nyangweso, Mary N. Maina, Nicholas Kiswi, Betty Chirchir, Marc Goldstein, and Quentin Awori
Solid state ^13C NMR spectroscopy provides direct evidence for reaction between ethinyl estradiol and a silicone elastomer vaginal ring drug delivery system, Clare F. McCoy, David C. Apperley, Bruce Variano, Heather Sussman, Dan Loeven, Peter Boyd, and R. Karl Malcolm
Study to evaluate the safety of griffithsin in a carrageenan gel in healthy women, Population Council
SUMOylation regulates germinal vesicle break-down and the AKT/PKB pathway during mouse oocyte maturation, Weber Beringui Feitosa and Patricia L. Morris
Therapeutic progestin segesterone acetate promotes neurogenesis: Implications for sustaining regeneration in female brain, Shuhua Chen, Narender Kumar, Zisu Mao, Régine Sitruk-Ware, and Roberta Diaz Brinton
Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: Updated indirect comparison meta-analysis, Agustin Conde-Agudelo, Roberto Romero, Eduardo Da Fonseca, John M. O'Brien, Elcin Cetingoz, George W. Creasy, Sonia S. Hassan, Offer Erez, Percy Pacora, and Kypros H. Nicolaides
Vangl2 regulates spermatid planar cell polarity through microtubule (MT)-based cytoskeleton in the rat testis, Haiqi Chen, Xiang Xiao, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
Submissions from 2017
Abcb1a and Abcb1b genes function differentially in blood–testis barrier dynamics in the rat, Linlin Su, C. Yan Cheng, Will M. Lee, Min Zhang, Fangfang Yang, Bin Zhao, Daishu Han, Yixun Liu, and Dahai Hu
Adjudin—A male contraceptive with anti-cancer, anti-neuroinflammation and anti-ototoxicity activities, Yan Ho Cheng, Weiliang Xia, Xiang Xiao, Elizabeth I. Tang, Haiqi Chen, Qing Wen, Ying Gao, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng
A fresh look at an old problem, Thomas Zydowsky
A model of genital herpes simplex virus Type 1 infection in Rhesus Macaques, Meropi Aravantinou, Ines Frank, Geraldine Arrode-Bruses, Moriah Szpara, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Nina Derby, and Elena Martinelli
An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques, Nina Derby, Meropi Aravantinou, Jessica Kenney, Shweta Ugaonkar, Asa Wesenberg, Jolanta Wilk, Larisa Kizima, Aixa Rodriguez, Shimin Zhang, Olga Mizenina, Keith Levendosky, Michael Cooney, Samantha Seidor, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, José Fernández-Romero, Thomas Zydowsky, and Melissa Robbiani
Annexin A2 is critical for blood-testis barrier integrity and spermatid disengagement in the mammalian testis, Katarzyna Chojnacka, Barbara Bilinska, and Dolores D. Mruk
Basement membrane laminin α2 regulates BTB dynamics via its effects on F-actin- and microtubule (MT)-cytoskeletons via mTORC1 signaling, Ying Gao, Haiqi Chen, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
Cell polarity, cell adhesion, and spermatogenesis: Role of cytoskeletons, Linxi Li, Ying Gao, Haiqi Chen, Tito T. Jesus, Elizabeth I. Tang, Nan Li, Qing-Quan Lian, Renshan Ge, and C. Yan Cheng
Drebrin and spermatogenesis, Haiqi Chen, Michelle W.M. Li, and C. Yan Cheng
Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance, Kenneth S.K. Tung, Jessica Harakal, Hui Qiao, Claudia Rival, Jonathan C.H. Li, Alberta G.A. Paul, Karen Wheeler, Patcharin Pramoonjago, Constance M. Grafer, Wei Sun, Robert D. Sampson, Elissa W.P. Wong, Prabhakara P. Reddi, Umesh S. Deshmukh, Daniel M. Hardy, Huanghui Tang, C. Yan Cheng, and Erwin Goldberg
Emerging role for mammalian target of rapamycin in male fertility, Pedro F. Oliveira, C. Yan Cheng, and Marco G. Alves
Experimental oral herpes simplex virus-1 (HSV-1) co-infection in simian immunodeficiency virus (SIV)-infected rhesus macaques, Meropi Aravantinou, Olga Mizenina, Giulia Calenda, Jessica Kenney, Ines Frank, Jeffrey D. Lifson, Moriah Szpara, Lichen Jing, David M. Koelle, Natalia Teleshova, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Elena Martinelli, and Nina Derby
Factors predicting improper use of a woman-controlled long-acting reversible contraceptive: Results from the acceptability study of a novel contraceptive vaginal ring, Bianca M. Stifani, Marlena Gehret Plagianos, Carolina Sales Vieira, and Ruth Merkatz
Focal adhesion kinase (FAK), Haiqi Chen and C. Yan Cheng
Human spermatogenesis and its regulation, Haiqi Chen, Dolores D. Mruk, Xiang Xiao, and C. Yan Cheng
Impact of various progestins with or without transdermal testosterone on gonadotropin levels for non-invasive hormonal male contraception: A randomized clinical trial, Michael Zitzmann, Julia Rohayem, J. Raidt, Sabine Kliesch, Narender Kumar, and Régine Sitruk-Ware
Lonidamine-ethyl ester-mediated remodelling of the Sertoli cell cytoskeleton induces phosphorylation of plakoglobin and promotes its interaction with α-catenin at the blood–testis barrier, Dolores D. Mruk, Michele Bonanomi, and Bruno Silvestrini
Mammalian target of rapamycin (mTOR): A central regulator of male fertility?, Tito T. Jesus, Pedro F. Oliveira, Mario Sousa, C. Yan Cheng, and Marco G. Alves
MAP/Microtubule affinity-regulating kinase, Elizabeth I. Tang and C. Yan Cheng
Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell differentiation culture system, Shou-Long Deng, Yan Zhang, Kun Yu, Xiu-Xia Wang, Su-Ren Chen, De-Ping Han, C. Yan Cheng, Zheng-Xing Lian, and Yi-Xun Liu
MIV-150 and zinc acetate combination provides potent and broad activity against HIV-1, Olga Mizenina, Mayla Hsu, Ninochka Jean-Pierre, Meropi Aravantinou, Keith Levendosky, Maria Gabriela Paglini, Thomas Zydowsky, Melissa Robbiani, and José Fernández-Romero
MZC gel inhibits SHIV-RT and HSV-2 in macaque vaginal mucosa and SHIV-RT in rectal mucosa, Giulia Calenda, Guillermo Villegas, Patrick Barnable, Claudia Litterst, Keith Levendosky, Agegnehu Gettie, Michael Cooney, James Blanchard, José Fernández-Romero, Thomas Zydowsky, and Natalia Teleshova
Nestorone® (NES) a novel progestin for non-oral contraception: Structure-activity relationships and brain metabolism studies, Narender Kumar, Jerome Fagart, Philippe Liere, Scott J. Mitchell, Alanah R. Knibb, Isabelle Petit-Topin, Marion Rame, Martine El-Etr, Michael Schumacher, Jeremy J. Lambert, Marie-Edith Rafestin-Oblin, and Régine Sitruk-Ware
Patent: Nestorone®/estradiol transdermal gel, Régine Sitruk-Ware, Dario Norberto Ramon Carrara, and Arnaud Grenier
Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2, Ying Gao, Haiqi Chen, Xiang Xiao, Wing-Yee Lui, Will M. Lee, Dolores D. Mruk, and C. Yan Cheng
Pixuna virus modifies host cell cytoskeleton to secure infection, Pedro Ignacio Gil, Guillermo Albrieu-Llinás, Estela Cecilia Mlewski, Marina Monetti, Laura Fozzatti, Cecilia Cuffini, José Fernández-Romero, Patricia Kunda, and Maria Gabriela Paglini
Regulation of spermatogenesis by a local functional axis in the testis: Role of the basement membrane–derived noncollagenous 1 domain peptide, Haiqi Chen, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Regulation of the blood–testis barrier by a local axis in the testis: Role of laminin α2 in the basement membrane, Ying Gao, Dolores D. Mruk, Haiqi Chen, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
Rescue of PFOS-induced human Sertoli cell injury by overexpressing a p-FAK-Y407E phosphomimetic mutant, Haiqi Chen, Ying Gao, Dolores D. Mruk, and C. Yan Cheng
Sperm release at spermiation is regulated by changes in the organization of actin- and microtubule-based cytoskeletons at the apical ectoplasmic specialization—A study using the adjudin model, Linxi Li, Elizabeth I. Tang, Haiqi Chen, Qing-Quan Lian, Renshan Ge, Bruno Silvestrini, and C. Yan Cheng
Submissions from 2016
A first-in-human trial of MIV-150 and zinc acetate co-formulated in a carrageenan gel: Safety, pharmacokinetics, acceptability, adherence and pharmacodynamics, Barbara Friedland, Craig Hoesley, Marlena Gehret Plagianos, Elena Hoskin, Shimin Zhang, Natalia Teleshova, Mohcine Alami, Lea Novak, Kyle Kleinbeck, Lauren L. Katzen, Thomas Zydowsky, José Fernández-Romero, and George W. Creasy
AKAP9, a regulator of microtubule dynamics, contributes to blood-testis barrier function, Deepak Venkatesh, Dolores D. Mruk, Jan M. Herter, Xavier Cullere, Katarzyna Chojnacka, C. Yan Cheng, and Tanya N. Mayadas
A novel microbicide/contraceptive intravaginal ring protects macaque genital mucosa against SHIV-RT infection ex vivo, Guillermo Villegas, Giulia Calenda, Shweta Ugaonkar, Shimin Zhang, Larisa Kizima, Olga Mizenina, Agegnehu Gettie, James Blanchard, Michael Cooney, Melissa Robbiani, José Fernández-Romero, Thomas Zydowsky, and Natalia Teleshova
A small molecule, which competes with MAdCAM-1, activates integrin α4β7 and fails to prevent mucosal transmission of SHIV-SF162P3, Geraldine Arrode-Bruses, Diana J. Goode, Kyle Kleinbeck, Jolanta Wilk, Ines Frank, Siddappa Byrareddy, James Arthos, Brooke Grasperge, James Blanchard, Thomas Zydowsky, Agegnehu Gettie, and Elena Martinelli
Baseline predictors of high adherence to a coitally dependent microbicide gel based on an objective marker of use: Findings from the Carraguard Phase 3 Trial, Barbara Friedland, Marie Stoner, Michelle Chau, Marlena Gehret Plagianos, Sumentheran N. Govender, Neetha S. Morar, Lydia Altini, Stephanie Skoler-Karpoff, Khatija Ahmed, Gita Ramjee, Constance Monedi, Robin A. Maguire, and Pekka Lahteenmaki
Biology of the Sertoli cell in the fetal, pubertal, and adult mammalian testis, Katarzyna Chojnacka, Marta Zarzycka, and Dolores D. Mruk
Cell polarity proteins and spermatogenesis, Ying Gao, Xiang Xiao, Wing-Yee Lui, Will M. Lee, Dolores D. Mruk, and C. Yan Cheng
Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption, Nan Li, Dolores D. Mruk, Ka-Wai Mok, Michelle W.M. Li, Chris K.C. Wong, Will M. Lee, Daishu Han, Bruno Silvestrini, and C. Yan Cheng
Development, function and fate of fetal Leydig cells, Qing Wen, C. Yan Cheng, and Yi-Xun Liu
Does cell polarity matter during spermatogenesis?, Ying Gao and C. Yan Cheng
Editorial: It is time for new male contraceptives!, Christina Wang, Régine Sitruk-Ware, and David Serfaty
Effective delivery of male contraceptives behind the blood-testis barrier (BTB)—Lesson from adjudin, Haiqi Chen, Dolores D. Mruk, Weiliang Xia, Michele Bonanomi, Bruno Silvestrini, and C. Yan Cheng
Emergent roles for intercellular adhesion molecule-1 in the restructuring of the blood-testis barrier during spermatogenesis in the mammal, Dolores D. Mruk