Submissions from 2009
Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence, Guo-Xin Hu, Qing-Quan Lian, Renshan Ge, Dianne O. Hardy, and Xiao-Kun Li
Phthalate levels and low birth weight: A nested case-control study of Chinese newborns, Yunhui Zhang, Ling Lin, Yang Cao, Bingheng Chen, Lixing Zheng, and Renshan Ge
Polarity proteins and cell–cell interactions in the testis, Elissa W.P. Wong and C. Yan Cheng
RAB13 participates in ectoplasmic specialization dynamics in the rat testis, Dolores D. Mruk and Ann S.N. Lau
Rates of serious infection after changes in regimens for medical abortion, Mary Fjerstad, James Trussell, Irving Sivin, E. Steve Lichtenberg, and Vanessa Cullins
Regulation of blood-testis barrier dynamics by focal adhesion kinase (FAK): An unexpected turn of events, C. Yan Cheng and Dolores D. Mruk
Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring, Joseph W. Romano, Bruce Variano, P. Coplan, J. Van Roey, K. Douville, Zeda Rosenberg, Marleen Temmerman, H. Verstraelen, L. Van Bortel, S. Weyers, and M. Mitchnick
Testicular cell junction: A novel target for male contraception, Nikki P.Y. Lee, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
TGF-β3 and TNFα perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: A new concept of BTB regulation during spermatogenesis, Weiliang Xia, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
The (+)- and (-)-gossypols potently inhibit human and rat 11β-hydroxysteroid dehydrogenase type 2, Bing-Bing Chen, Han Lin, Guo-Xin Hu, Ying Su, Hong-Yu Zhou, Qing-Quan Lian, Hui Cai, Dianne O. Hardy, Ding-Ying Gu, and Renshan Ge
Tonsillar application of AT-2 SIV affords partial protection against rectal challenge with SIVmac239, Panagiotis Vagenas; Vennansha G. Williams; Michael Piatak, Jr.; Julian W. Bess; Jeffrey D. Lifson; James Blanchard; Agegnehu Gettie; and Melissa Robbiani
Transcription regulation in spermatogenesis, Wing-Yee Lui and C. Yan Cheng
Unexpected heaping in reported gestational age for women undergoing medical abortion, Irving Sivin, James Trussell, E. Steve Lichtenberg, Mary Fjerstad, Kelly Cleland, and Vanessa Cullins
Value of serum antisperm antibodies in diagnosing obstructive azoospermia, Richard Lee, Marc Goldstein, Brant W. Ullery, Joshua Ehrlich, Marc Soares, Renee A. Razzano, Michael Herman, Mark A. Callahan, Philip S. Li, Peter N. Schlegel, and Steven S. Witkin
Submissions from 2008
Adult varicocele, Howard H. Kim and Marc Goldstein
A fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells, Ines Frank, Hella Stössel, Agegnehu Gettie, Stuart G. Turville, Julian W. Bess, Jeffrey D. Lifson, Irving Sivin, Nikolaus Romani, and Melissa Robbiani
An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis, Helen H.N. Yan, Dolores D. Mruk, Elissa W.P. Wong, Will M. Lee, and C. Yan Cheng
Anchoring junctions as drug targets: Role in contraceptive development, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng
A randomized, placebo-controlled trial to assess the safety and acceptability of use of carraguard vaginal gel by heterosexual couples in Thailand, Peter H. Kilmarx, Kelly Blanchard, Supaporn Chaikummao, Barbara Friedland, Nucharee Srivirojana, Cathy Connolly, Paisit Witwatwongwana, Somsak Supawitkul, Philip A. Mock, Thanyanan Chaowanachan, and Jordan W. Tappero
Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Candida albicans-induced DC activation partially restricts HIV amplification in DCs and increases DC to T-cell spread of HIV, Laurence Vachot, Vennansha G. Williams, Julian W. Bess, Jeffrey D. Lifson, and Melissa Robbiani
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics, Andreas Schweizer, Peter Rusert, Livia Berlinger, Claudia R. Ruprecht, Axel Mann, Stéphanie Corthesy, Stuart G. Turville, Meropi Aravantinou, Marek Fischer, Melissa Robbiani, Patrick Amstutz, and Alexandra Trkola
Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion, Xiao-Dong Fu, Maria Silva Giretti, Lorenzo Goglia, Marina Ines Flamini, Angel Matias Sanchez, Chiara Baldacci, Silvia Garibaldi, Régine Sitruk-Ware, Andrea R. Genazzani, and Tommaso Simoncini
Cross-talk between tight and anchoring junctions: Lesson from the testis, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Cyclic 3′,5′-AMP causes ADAM1/ADAM2 to rapidly diffuse within the plasma membrane of guinea pig sperm, Gary R. Hunnicutt, Dennis E. Koppel, Susanna Kwitny, and Ann E. Cowan
Delivering non-hormonal contraceptives to men: Advances and obstacles, Dolores D. Mruk and C. Yan Cheng
Delivery of contraceptives to men: Lesson from other therapeutic drugs, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: An integrated analysis, Peter Y. Liu, Ronald S. Swerdloff, Bradley D. Anawalt, Richard A. Anderson, William J. Bremner, Joerg Elliesen, Yi-Qun Gu, Wendy M. Kersemaekers, Robert I. McLachlan, M. Cristina Meriggiola, Eberhard Nieschlag, Régine Sitruk-Ware, Kirsten M. Vogelsong, Xing-Hai Wang, Frederick C.W. Wu, Michael Zitzmann, David J. Handelsman, and Christina Wang
Does estrogen therapy reduce coronary artery calcification in postmenopausal women?, Régine Sitruk-Ware
Dynamins, spermatogenesis and contraceptive development, Pearl P.Y. Lie, Dolores D. Mruk, and C. Yan Cheng
Efficacy of Carraguard®-based microbicides in vivo despite variable in vitro activity, Stuart G. Turville, Meropi Aravantinou, Todd Miller, Jessica Kenney, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M. Zydowsky, Michael Piatak Jr., Julian W. Bess Jr., Jeffrey D. Lifson, James Blanchard, Agegnehu Gettie, and Melissa Robbiani
Efficacy of Carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebo-controlled trial, Stephanie Skoler-Karpoff, Gita Ramjee, Khatija Ahmed, Lydia Altini, Marlena Gehret Plagianos, Barbara Friedland, Sumen Govender, Alana de Kock, Nazira Cassim, Thesla Palanee, Gregory Dozier, Robin A. Maguire, and Pekka Lahteenmaki
Endocrine manipulation in male infertility, Howard H. Kim and Peter N. Schlegel
Feline immunodeficiency virus dendritic cell infection and transfer, Wendy S. Sprague, Melissa Robbiani, Paul R. Avery, Kevin P. O'Halloran, and Edward A. Hoover
Identification and characterization of the minimal androgen-regulated kidney-specific kidney androgen-regulated protein gene promoter, Liqiang Fan, Dianne O. Hardy, James F. Catteral, Jian Zhao, and Suxia Li
Inhibition of 11β-hydroxysteroid dehydrogenase enzymatic activities by glycyrrhetinic acid in vivo supports direct glucocorticoid-mediated suppression of steroidogenesis in leydig cells, Guo-Xin Hu, Han Lin, Chantal M. Sottas, David J. Morris, Matthew P. Hardy, and Renshan Ge
Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat, Oli Sarkar, Premendu P. Mathur, C. Yan Cheng, and Dolores D. Mruk
Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero, Han Lin, Renshan Ge, Guo-Rong Chen, Guo-Xin Hu, Lei Dong, Qing-Quan Lian, Dianne O. Hardy, Chantal M. Sottas, Xiao-Kun Li, and Matthew P. Hardy
Microbicide product development, Robin A. Maguire
Microbicides: Chemistry, structure, and strategy, Thomas Zydowsky
Modulation of 11β-hydroxysteroid dehydrogenase expression by bombesin: A possible mechanism for glucocorticoid resistance in androgen independent prostate cancer, J.G. Lee, Renshan Ge, Dianne O. Hardy, K. Leong, D.M. Nanus, Matthew P. Hardy, and R. Shen
Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2, Thomas M. Onorato, Petrice W. Brown, and Patricia L. Morris
New perspectives in non-hormonal male contraception, Dolores D. Mruk
New vistas in contraceptive technology, Saumya Ramarao, Régine Sitruk-Ware, and John Townsend
Nitric oxide-cGMP signaling: Its role in cell junction dynamics during spermatogenesis, Oli Sarkar, Premendu P. Mathur, and Dolores D. Mruk
Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis, Elissa W.P. Wong, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Progesterone and progestins: Neuroprotection and myelin repair, Michael Schumacher, Régine Sitruk-Ware, and Alejandro De Nicola
Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells, Qin Xu, Noriyuki Ohara, Jin Liu, Mariko Amano, Régine Sitruk-Ware, Shigeki Yoshida, and Takeshi Maruo
Rapid mechanisms of glucocorticoid signaling in the Leydig cell, Guo-Xin Hu, Qing-Quan Lian, Han Lin, Syed A. Latif, David J. Morris, Matthew P. Hardy, and Renshan Ge
Reassessing reconstruction in the management of obstructive azoospermia: Reconstruction or sperm acquisition?, Richard Lee, Philip S. Li, Peter N. Schlegel, and Marc Goldstein
Resolution of de novo HIV production and trafficking in immature dendritic cells, Stuart G. Turville, Meropi Aravantinou, Hella Stoessel, Nikolaus Romani, and Melissa Robbiani
Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men, Petrice W. Brown, KeumSil Hwang, Peter N. Schlegel, and Patricia L. Morris
Sphingomyelin synthases and testicular function, Nikki P.Y. Lee, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
"Unlocking" the blood-testis barrier and the ectoplasmic specialization by cytokines during spermatogenesis: Emerging targets for male contraception, Michelle W.M. Li, Dolores D. Mruk, and C. Yan Cheng
Submissions from 2007
7α-methyl-19-nortestosterone (MENT) vs testosterone in combination with etonogestrel implants for spermatogenic suppression in healthy men, Melanie J. Walton, Narender Kumar, David T. Baird, Helen Ludlow, and Richard A. Anderson
Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa, Gita Ramjee, Neetha S. Morar, Sarah Braunstein, Barbara Friedland, Heidi E. Jones, and Janneke van de Wijgert
An initial pharmacokinetic study with a Metered Dose Transdermal System® for delivery of the progestogen Nestorone® as a possible future contraceptive, Ian S. Fraser, Edith Weisberg, Narender Kumar, Sushma Kumar, Andrew J. Humberstone, Louise McCrossin, Deborah Shaw, Yun-yen Tsong, and Régine Sitruk-Ware
A seamless trespass: Germ cell migration across the seminiferous epithelium during spermatogenesis, Claire Q.F. Wang and C. Yan Cheng
Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats, Renshan Ge, Guo-Rong Chen, Qiang Dong, Benson T. Akingbemi, Chantal M. Sottas, Michelle Santos, Stuart C. Sealfon, Daniel J. Bernard, and Matthew P. Hardy
Carrageenan/MIV-150 (PC-815), a combination microbicide, José Fernández-Romero, Mitchell Thorn, Stuart G. Turville, Kanani Titchen, Kristin M. Sudol, Jifan Li, Todd Miller, Melissa Robbiani, Robin A. Maguire, Robert W. Buckheit Jr., Tracy L. Hartman, and David M. Phillips
Cellular localization of sphingomyelin synthase 2 in the seminiferous epithelium of adult rat testes, Nikki P.Y. Lee, Dolores D. Mruk, Weiliang Xia, and C. Yan Cheng
Comparison of the impact of vaginal and oral administration of combined hormonal contraceptives on hepatic proteins sensitive to estrogen, Régine Sitruk-Ware, Joel Menard, Mandana Rad, Jacobus Burggraaf, Marieke L. de Kam, Barbara A. Tokay, Irving Sivin, and Cornelis Kluft
Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface, Claire Q.F. Wang, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
C-type natriuretic peptide regulates blood-testis barrier dynamics in adult rat testes, Weiliang Xia, Dolores D. Mruk, and C. Yan Cheng
Current concepts of HIV transmission, Gavin Morrow, Laurence Vachot, Panagiotis Vagenas, and Melissa Robbiani
Determining the feasibility of utilizing the microbicide applicator compliance assay for use in clinical trials, Andrea R. Wallace, Aaron Teitelbaum, Livia Wan, Maria Gloria Mulima, Laura Guichard, Stephanie Skoler, Hlengiwe Vilakazi, Fridda S. Mapula, Jasmine Rossier, Sumentheran N. Govender, Pekka Lahteenmaki, Robin A. Maguire, and David M. Phillips
Development of a cryopreservation protocol for Leydig cells, Guo-Rong Chen, Renshan Ge, Han Lin, Lei Dong, Chantal M. Sottas, and Matthew P. Hardy
Ectoplasmic specialization: A friend or a foe of spermatogenesis?, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Effect of a single vaginal administration of levonorgestrel in Carraguard® gel on the ovulatory process: A potential candidate for "dual protection" emergency contraception, Vivian Brache, Horacio B. Croxatto, Régine Sitruk-Ware, Robin A. Maguire, Juan Carlos Montero, Narender Kumar, Ana Maria Salvatierra, Ana Sofia Tejada, Leila Cochon, María Luisa Forcelledo, Pekka Lahteenmaki, Francisco Alvarez, and Anibal Faundes
Effects of estradiol with oral or intravaginal progesterone on risk markers for breast cancer in a postmenopausal monkey model, Charles E. Wood, Régine Sitruk-Ware, Yun-yen Tsong, Thomas C. Register, Cynthia J. Lees, and J. Mark Cline
Effects of levonorgestrel-releasing IUS and progesterone receptor modulator PRM CDB-2914 on uterine leiomyomas, Takeshi Maruo, Noriyuki Ohara, Hiroya Matsuo, Qin Xu, Wei Chen, Régine Sitruk-Ware, and Elof D.B. Johansson
Effects of oral and transvaginal ethinyl estradiol on hemostatic factors and hepatic proteins in a randomized, crossover study, Régine Sitruk-Ware, Genevieve Plu-Bureau, Joel Menard, Jacqueline Conard, Sushma Kumar, Jean-Christophe Thalabard, Barbara A. Tokay, and Philippe Bouchard
Gene expression during development of fetal and adult Leydig cells, Lei Dong, Scott A. Jelinsky, Joshua N. Finger, Daniel S. Johnston, Gregory S. Kopf, Chantal M. Sottas, Matthew P. Hardy, and Renshan Ge
GM1 dynamics as a marker for membrane changes associated with the process of capacitation in murine and bovine spermatozoa, Vimal Selvaraj, Danielle E. Buttke, Atsushi Asano, John L. McElwee, Collin A. Wolff, Jacquelyn L. Nelson, Angela V. Klaus, Gary R. Hunnicutt, and Alexander J. Travis
Hormone therapy effects on social behavior and activity levels of surgically postmenopausal cynomolgus monkeys, Carol A. Shively, Charles E. Wood, Thomas C. Register, Stephanie L. Willard, Cynthia J. Lees, Haiying Chen, Régine Sitruk-Ware, Yun-yen Tsong, and J. Mark Cline
Junction restructuring and spermatogenesis: The biology, regulation, and implication in male contraceptive development, Helen H.N. Yan, Dolores D. Mruk, and C. Yan Cheng
New hormonal therapies and regimens in the postmenopause: Routes of administration and timing of initiation, Régine Sitruk-Ware
Pharmacokinetic study to compare the absorption and tolerability of two doses of levonorgestrel following single vaginal administration of levonorgestrel in Carraguard® gel: A new formulation for "dual protection" contraception, Régine Sitruk-Ware, Vivian Brache, Robin A. Maguire, Horacio B. Croxatto, Narender Kumar, Sushma Kumar, Juan Carlos Montero, Ana Maria Salvatierra, David M. Phillips, and Anibal Faundes
Phthalate ester toxicity in Leydig cells: Developmental timing and dosage considerations, Renshan Ge, Guo-Rong Chen, Cigdem Tanrikut, and Matthew P. Hardy
Preclinical and clinical properties of trimegestone: A potent and selective progestin, Régine Sitruk-Ware, Ronald Bossemeyer, and Phillipe Bouchard
Rab4A GTPase-catenin interactions are involved in cell junction dynamics in the testis, Dolores D. Mruk, Ann S.N. Lau, Oli Sarkar, and Weiliang Xia
Regulation of cell junction dynamics by cytokines in the testis—A molecular and biochemical perspective, Wing Yee Lui and C. Yan Cheng
Routes of delivery for progesterone and progestins, Régine Sitruk-Ware
Special issue on intrauterine devices and systems, Régine Sitruk-Ware and Peter J. Donaldson
Targeted and reversible disruption of the blood-testis barrier by an FSH mutant-occludin peptide conjugate, Ching-hang Wong, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Testosterone production in mice lacking inducible nitric oxide synthase expression is sensitive to restraint stress, Ben-Avi Weissman, Chantal M. Sottas, Ping Zhou, Costantino Iadecola, and Matthew P. Hardy
The levonorgestrel intrauterine system for use in peri- and postmenopausal women, Régine Sitruk-Ware
Unraveling the molecular targets pertinent to junction restructuring events during spermatogenesis using the Adjudin-induced germ cell depletion model, Weiliang Xia, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Utility and drawbacks of continuous use of a copper T IUD for 20 years, Irving Sivin
Submissions from 2006
Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions, Oli Sarkar, Weiliang Xia, and Dolores D. Mruk
A male contraceptive targeting germ cell adhesion, Dolores D. Mruk, Ching-hang Wong, Bruno Silvestrini, and C. Yan Cheng
A multistep kinase-based Sertoli cell autocrine-amplifying loop regulates prostaglandins, their receptors, and cytokines, Tomomoto Ishikawa and Patricia L. Morris
A novel class of small RNAs bind to MILI protein in mouse testes, Alexei Aravin, Dimos Gaidatzis, Sebastien Pfeffer, Mariana Lagos-Quintana, Pablo Landgraf, Nicola Iovino, Patricia L. Morris, Michael J. Brownstein, Satomi Kuramochi-Miyagawa, Toru Nakano, Minchen Chien, James J. Russo, Jingyue Ju, Robert Sheridan, Chris Sander, Mihaela Zavolan, and Thomas Tuschl
A novel pathway involving progesterone receptor, endothelin-2, and endothelin receptor B controls ovulation in mice, Gopinath S. Palanisamy, Yong-Pil Cheon, Jaeyeon Kim, Athilakshmi Kannan, Quanxi Li, Marcey Sato, Srinivasa R. Mantena, Régine Sitruk-Ware, Milan K. Bagchi, and Indrani C. Bagchi
Comparative effects of a contraceptive vaginal ring delivering a nonandrogenic progestin and continuous ethinyl estradiol and a combined oral contraceptive containing levonorgestrel on hemostasis variables, Mandana Rad, Cornelis Kluft, Joel Ménard, Jacobus Burggraaf, Marieke L. de Kam, Piet Meijer, Irving Sivin, and Régine Sitruk-Ware
Contraception: An international perspective, Régine Sitruk-Ware
CpG-C ISS-ODN activation of blood-derived B cells from healthy and chronic immunodeficiency virus-infected macaques, Natalia Teleshova, Jessica Kenney, Vennansha G. Williams, Gary Van Nest, Jason Marshall, Jeffrey D. Lifson, Irving Sivin, Jason Dufour, Rudolf Bohm, Agegnehu Gettie, and Melissa Robbiani
Cyclical mastalgia and breast cancer risk: Results of a French cohort study, Genevieve Plu-Bureau, Monique G. Lê, Régine Sitruk-Ware, and Jean-Christophe Thalabard
Day of Dialogue on Public Sector Pricing of Pharmaceutical Products, Population Council