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Submissions from 2010
State-of-the-art of non-hormonal methods of contraception: I. Mechanical barrier contraception, I. Batar and Irving Sivin
State-of-the-art of non-hormonal methods of contraception: IV. Natural family planning, G. Freundl, Irving Sivin, and I. Batar
State-of-the-art of non-hormonal methods of contraception: IV. Natural family planning, G. Freundl, Irving Sivin, and I. Batar
Structure-dependent inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 activities by phthalates, Binghai Zhao, Yanhui Chu, Ya-Dong Huang, Dianne O. Hardy, Shaoqiang Lin, and Renshan Ge
The annulus of the mouse sperm tail is required to establish a membrane diffusion barrier that is engaged during the late steps of spermiogenesis, Susanna Kwitny, Angela V. Klaus, and Gary R. Hunnicutt
The biology of spermatogenesis: The past, present and future, C. Yan Cheng and Dolores D. Mruk
The use of newer progestins for contraception, Régine Sitruk-Ware and Anita Nath
The use of newer progestins for contraception, Régine Sitruk-Ware and Anita Nath
Tight junctions in the testis: New perspectives, Dolores D. Mruk and C. Y. Cheng
Submissions from 2009
14-3-3 and its binding partners are regulators of protein-protein interactions during spermatogenesis, Shengyi Sun, Elissa W.P. Wong, Michelle W.M. Li, Will M. Lee, and C. Yan Cheng
14-3-3 protein regulates cell adhesion in the seminiferous epithelium of rat testes, Elissa W.P. Wong, Shengyi Sun, Michelle W.M. Li, Will M. Lee, and C. Yan Cheng
Acceptability of a Carrageenan-based candidate vaginal microbicide and matching placebo: Findings from a Phase II safety trial among women in Chiang Rai, Thailand, Heidi E. Jones, Supaporn Chaikummao, Janneke van de Wijgert, Barbara Friedland, Chomnad Manopaiboon, Paisit Witwatwongwana, Mayuree Wankrairot, Nartlada Chantharojwong, and Peter H. Kilmarx
Activins regulate 17β-hydroxysteroid dehydrogenase type I transcription in murine gonadotrope cells, Beata Bak, Laura Carpio, Jinjing L. Kipp, Pankaj Lamba, Ying Wang, Renshan Ge, Matthew P. Hardy, Kelly E. Mayo, and Daniel J. Bernard
A decision analysis of treatments for nonobstructive azoospermia associated with varicocele, Richard Lee, Philip S. Li, Marc Goldstein, Glenn Schattman, and Peter N. Schlegel
Adjudin targeting rabbit germ cell adhesion as a male contraceptive: A pharmacokinetics study, Guo-Xin Hu, Lu-Feng Hu, Dai-Zheng Yang, Jun-Wei Li, Guo-Rong Chen, Bing-Bing Chen, Dolores D. Mruk, Michele Bonanomi, Bruno Silvestrini, C. Yan Cheng, and Renshan Ge
A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy, Federica Crostarosa, Meropi Aravantinou, Onome J. Akpogheneta, Edith Jasny, Andrew Shaw, Jessica Kenney, Michael Piatak Jr., Jeffrey D. Lifson, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M. Zydowsky, James Blanchard, Agegnehu Gettie, and Melissa Robbiani
An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: A biochemical and molecular perspective, C. Yan Cheng and Dolores D. Mruk
An in vivo study on adjudin and blood-testis barrier dynamics, Ilona A. Kopera, Linlin Su, Barbara Bilínska, C. Yan Cheng, and Dolores D. Mruk
An occludin-focal adhesion kinase protein complex at the blood-testis barrier: A study using the cadmium model, Erica R. Siu, Elissa W.P. Wong, Dolores D. Mruk, K.L. Sze, Catarina S. Porto, and C. Yan Cheng
Cadmium-induced testicular injury, Erica R. Siu, Dolores D. Mruk, Catarina S. Porto, and C. Yan Cheng
Central modifications of allopregnanolone and β-endorphin following subcutaneous administration of Nestorone, E. Lenzi, N. Pluchino, S. Begliuomini, E. Casarosa, S. Merlini, A. Giannini, M. Luisi, Narender Kumar, Régine Sitruk-Ware, and A.R. Genazzani
Characterization of a novel gain of function glucocorticoid receptor knock-in mouse, Junhui Zhang, Renshan Ge, Catherine Matte-Martone, Julie Goodwin, Warren D. Shlomchik, Mark J. Mamula, Ali Kooshkabadi, Matthew P. Hardy, and David Geller
Combined transdermal testosterone gel and the progestin Nestorone suppresses serum gonadotropins in men, Vahid Mahabadi, John K. Amory, Ronald S. Swerdloff, William J. Bremner, Stephanie T. Page, Régine Sitruk-Ware, Peter D. Christensen, Narender Kumar, Yun-yen Tsong, Diana Blithe, and Christina Wang
Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Coordinating cellular events during spermatogenesis: A biochemical model, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk
Cytokines and junction restructuring events during spermatogenesis in the testis: An emerging concept of regulation, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Deprival of testicular innervation induces apoptosis of Leydig cells via caspase-8-dependent signaling: A novel survival pathway revealed, Yong-Guang Gong, Yi-Qiu Wang, Min Gu, Ming-Ming Feng, Wei Zhang, and Renshan Ge
Different cardiovascular effects of progestins according to structure and activity, Anita Nath and Régine Sitruk-Ware
Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying blood-testis barrier dynamics?, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Distribution, metabolism and excretion of a synthetic androgen 7α-methyl-19-nortestosterone, a potential male-contraceptive, Pramod Vishwanath Prasad, Ramamani Arumugam, Mark Willman, Renshan Ge, Régine Sitruk-Ware, and Narender Kumar
Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G, Susanna Trapp, Nina Derby, Rachel Singer, Andrew Shaw, Vennansha G. Williams, Stuart G. Turville, Julian W. Bess Jr., Jeffrey D. Lifson, and Melissa Robbiani
Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier, Linlin Su, C. Yan Cheng, and Dolores D. Mruk
Effectiveness of medical abortion with mifepristone and buccal misoprostol through 59 gestational days, Mary Fjerstad, Irving Sivin, E. Steve Lichtenberg, James Trussell, Kelly Cleland, and Vanessa Cullins
Effect of sexual intercourse on the absorption of levonorgestrel after vaginal administration of 0.75 mg in Carraguard® gel: A randomized, cross-over, pharmacokinetic study, Vivian Brache, Horacio B. Croxatto, Narender Kumar, Régine Sitruk-Ware, Leila Cochón, Veronica Schiappacasse, Irving Sivin, Carla Muñoz, Robin A. Maguire, and Anibal Faundes
Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium, Pearl P.Y. Lie, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Extracellular matrix and its role in spermatogenesis, Michelle K.Y. Siu and C. Yan Cheng
Focal adhesion kinase is a blood-testis barrier regulator, Erica R. Siu, Elissa W.P. Wong, Dolores D. Mruk, Catarina S. Porto, and C. Yan Cheng
Increased proliferation but decreased steroidogenic capacity in Leydig cells from mice lacking cyclin-dependent kinase inhibitor 1B, Han Lin, Guo-Xin Hu, Lei Dong, Qiang Dong, Motoko Mukai, Bing-Bing Chen, Denise R. Holsberger, Chantal M. Sottas, Paul S. Cooke, Qing-Quan Lian, Xiao-Kun Li, and Renshan Ge
In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats, Han Lin, Qing-Quan Lian, Guo-Xin Hu, Yuan Jin, Yunhui Zhang, Dianne O. Hardy, Guo-Rong Chen, Zhong-Qiu Lu, Chantal M. Sottas, Matthew P. Hardy, and Renshan Ge
Leydig cells: From stem cells to aging, Haolin Chen, Renshan Ge, and Barry R. Zirkin
Meta-analysis of 200 or 600 mg mifepristone in association with two prostaglandins for termination of early pregnancy, Michel Lièvre and Régine Sitruk-Ware
Methods for female contraception: A model for innovation in drug delivery systems, Ruth Merkatz, Barbara A. Tokay, and Régine Sitruk-Ware
Mitogen-activated protein kinases in male reproductive function, Michelle W.M. Li, Dolores D. Mruk, and C. Yan Cheng
Mono-(2-ethylhexyl) phthalate (MEHP) regulates glucocorticoid metabolism through 11β-hydroxysteroid dehydrogenase 2 in murine gonadotrope cells, Dun Hong, Xing-Wang Li, Qing-Quan Lian, Pankaj Lamba, Daniel J. Bernard, Dianne O. Hardy, Hai-Xiao Chen, and Renshan Ge
Nitric oxide and cyclic nucleotides: Their roles in junction dynamics and spermatogenesis, Nikki P.Y. Lee and C. Yan Cheng
Normal responses to restraint stress in mice lacking the gene for neuronal nitric oxide synthase, Ben-Avi Weissman, Chantal M. Sottas, Michael Holmes, Ping Zhou, Costantino Iadecola, Dianne O. Hardy, Renshan Ge, and Matthew P. Hardy
Novel non-oral hormonal contraceptive methods for women, Anita Nath and Régine Sitruk-Ware
Parenteral administration of progestins for hormonal replacement therapy, Anita Nath and Régine Sitruk-Ware
Peptidergic not monoaminergic fibers profusely innervate the young adult human testis, Yong-Guang Gong, Ming-Ming Feng, Xiang-Nong Hu, Yi-Qiu Wang, Min Gu, Wei Zhang, and Renshan Ge
Pharmacology and clinical applications of selective estrogen receptor modulators, Anita Nath and Régine Sitruk-Ware
Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence, Guo-Xin Hu, Qing-Quan Lian, Renshan Ge, Dianne O. Hardy, and Xiao-Kun Li
Phthalate levels and low birth weight: A nested case-control study of Chinese newborns, Yunhui Zhang, Ling Lin, Yang Cao, Bingheng Chen, Lixing Zheng, and Renshan Ge
Polarity proteins and cell–cell interactions in the testis, Elissa W.P. Wong and C. Yan Cheng
RAB13 participates in ectoplasmic specialization dynamics in the rat testis, Dolores D. Mruk and Ann S.N. Lau
Rates of serious infection after changes in regimens for medical abortion, Mary Fjerstad, James Trussell, Irving Sivin, E. Steve Lichtenberg, and Vanessa Cullins
Regulation of blood-testis barrier dynamics by focal adhesion kinase (FAK): An unexpected turn of events, C. Yan Cheng and Dolores D. Mruk
Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring, Joseph W. Romano, Bruce Variano, P. Coplan, J. Van Roey, K. Douville, Zeda Rosenberg, Marleen Temmerman, H. Verstraelen, L. Van Bortel, S. Weyers, and M. Mitchnick
Testicular cell junction: A novel target for male contraception, Nikki P.Y. Lee, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
TGF-β3 and TNFα perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: A new concept of BTB regulation during spermatogenesis, Weiliang Xia, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
The (+)- and (-)-gossypols potently inhibit human and rat 11β-hydroxysteroid dehydrogenase type 2, Bing-Bing Chen, Han Lin, Guo-Xin Hu, Ying Su, Hong-Yu Zhou, Qing-Quan Lian, Hui Cai, Dianne O. Hardy, Ding-Ying Gu, and Renshan Ge
Tonsillar application of AT-2 SIV affords partial protection against rectal challenge with SIVmac239, Panagiotis Vagenas; Vennansha G. Williams; Michael Piatak, Jr.; Julian W. Bess; Jeffrey D. Lifson; James Blanchard; Agegnehu Gettie; and Melissa Robbiani
Transcription regulation in spermatogenesis, Wing-Yee Lui and C. Yan Cheng
Unexpected heaping in reported gestational age for women undergoing medical abortion, Irving Sivin, James Trussell, E. Steve Lichtenberg, Mary Fjerstad, Kelly Cleland, and Vanessa Cullins
Value of serum antisperm antibodies in diagnosing obstructive azoospermia, Richard Lee, Marc Goldstein, Brant W. Ullery, Joshua Ehrlich, Marc Soares, Renee A. Razzano, Michael Herman, Mark A. Callahan, Philip S. Li, Peter N. Schlegel, and Steven S. Witkin
Submissions from 2008
Adult varicocele, Howard H. Kim and Marc Goldstein
A fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells, Ines Frank, Hella Stössel, Agegnehu Gettie, Stuart G. Turville, Julian W. Bess, Jeffrey D. Lifson, Irving Sivin, Nikolaus Romani, and Melissa Robbiani
An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis, Helen H.N. Yan, Dolores D. Mruk, Elissa W.P. Wong, Will M. Lee, and C. Yan Cheng
Anchoring junctions as drug targets: Role in contraceptive development, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng
A randomized, placebo-controlled trial to assess the safety and acceptability of use of carraguard vaginal gel by heterosexual couples in Thailand, Peter H. Kilmarx, Kelly Blanchard, Supaporn Chaikummao, Barbara Friedland, Nucharee Srivirojana, Cathy Connolly, Paisit Witwatwongwana, Somsak Supawitkul, Philip A. Mock, Thanyanan Chaowanachan, and Jordan W. Tappero
Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Candida albicans-induced DC activation partially restricts HIV amplification in DCs and increases DC to T-cell spread of HIV, Laurence Vachot, Vennansha G. Williams, Julian W. Bess, Jeffrey D. Lifson, and Melissa Robbiani
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics, Andreas Schweizer, Peter Rusert, Livia Berlinger, Claudia R. Ruprecht, Axel Mann, Stéphanie Corthesy, Stuart G. Turville, Meropi Aravantinou, Marek Fischer, Melissa Robbiani, Patrick Amstutz, and Alexandra Trkola
Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion, Xiao-Dong Fu, Maria Silva Giretti, Lorenzo Goglia, Marina Ines Flamini, Angel Matias Sanchez, Chiara Baldacci, Silvia Garibaldi, Régine Sitruk-Ware, Andrea R. Genazzani, and Tommaso Simoncini
Cross-talk between tight and anchoring junctions: Lesson from the testis, Helen H.N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Cyclic 3′,5′-AMP causes ADAM1/ADAM2 to rapidly diffuse within the plasma membrane of guinea pig sperm, Gary R. Hunnicutt, Dennis E. Koppel, Susanna Kwitny, and Ann E. Cowan
Delivering non-hormonal contraceptives to men: Advances and obstacles, Dolores D. Mruk and C. Yan Cheng
Delivery of contraceptives to men: Lesson from other therapeutic drugs, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: An integrated analysis, Peter Y. Liu, Ronald S. Swerdloff, Bradley D. Anawalt, Richard A. Anderson, William J. Bremner, Joerg Elliesen, Yi-Qun Gu, Wendy M. Kersemaekers, Robert I. McLachlan, M. Cristina Meriggiola, Eberhard Nieschlag, Régine Sitruk-Ware, Kirsten M. Vogelsong, Xing-Hai Wang, Frederick C.W. Wu, Michael Zitzmann, David J. Handelsman, and Christina Wang
Does estrogen therapy reduce coronary artery calcification in postmenopausal women?, Régine Sitruk-Ware
Dynamins, spermatogenesis and contraceptive development, Pearl P.Y. Lie, Dolores D. Mruk, and C. Yan Cheng
Efficacy of Carraguard®-based microbicides in vivo despite variable in vitro activity, Stuart G. Turville, Meropi Aravantinou, Todd Miller, Jessica Kenney, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M. Zydowsky, Michael Piatak Jr., Julian W. Bess Jr., Jeffrey D. Lifson, James Blanchard, Agegnehu Gettie, and Melissa Robbiani
Efficacy of Carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebo-controlled trial, Stephanie Skoler-Karpoff, Gita Ramjee, Khatija Ahmed, Lydia Altini, Marlena Gehret Plagianos, Barbara Friedland, Sumen Govender, Alana de Kock, Nazira Cassim, Thesla Palanee, Gregory Dozier, Robin A. Maguire, and Pekka Lahteenmaki
Endocrine manipulation in male infertility, Howard H. Kim and Peter N. Schlegel
Feline immunodeficiency virus dendritic cell infection and transfer, Wendy S. Sprague, Melissa Robbiani, Paul R. Avery, Kevin P. O'Halloran, and Edward A. Hoover
Identification and characterization of the minimal androgen-regulated kidney-specific kidney androgen-regulated protein gene promoter, Liqiang Fan, Dianne O. Hardy, James F. Catteral, Jian Zhao, and Suxia Li
Inhibition of 11β-hydroxysteroid dehydrogenase enzymatic activities by glycyrrhetinic acid in vivo supports direct glucocorticoid-mediated suppression of steroidogenesis in leydig cells, Guo-Xin Hu, Han Lin, Chantal M. Sottas, David J. Morris, Matthew P. Hardy, and Renshan Ge
Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat, Oli Sarkar, Premendu P. Mathur, C. Yan Cheng, and Dolores D. Mruk
Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero, Han Lin, Renshan Ge, Guo-Rong Chen, Guo-Xin Hu, Lei Dong, Qing-Quan Lian, Dianne O. Hardy, Chantal M. Sottas, Xiao-Kun Li, and Matthew P. Hardy
Microbicide product development, Robin A. Maguire
Microbicides: Chemistry, structure, and strategy, Thomas Zydowsky
Modulation of 11β-hydroxysteroid dehydrogenase expression by bombesin: A possible mechanism for glucocorticoid resistance in androgen independent prostate cancer, J.G. Lee, Renshan Ge, Dianne O. Hardy, K. Leong, D.M. Nanus, Matthew P. Hardy, and R. Shen
Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2, Thomas M. Onorato, Petrice W. Brown, and Patricia L. Morris
New perspectives in non-hormonal male contraception, Dolores D. Mruk
New vistas in contraceptive technology, Saumya Ramarao, Régine Sitruk-Ware, and John Townsend
Nitric oxide-cGMP signaling: Its role in cell junction dynamics during spermatogenesis, Oli Sarkar, Premendu P. Mathur, and Dolores D. Mruk
Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis, Elissa W.P. Wong, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Progesterone and progestins: Neuroprotection and myelin repair, Michael Schumacher, Régine Sitruk-Ware, and Alejandro De Nicola
Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells, Qin Xu, Noriyuki Ohara, Jin Liu, Mariko Amano, Régine Sitruk-Ware, Shigeki Yoshida, and Takeshi Maruo
Rapid mechanisms of glucocorticoid signaling in the Leydig cell, Guo-Xin Hu, Qing-Quan Lian, Han Lin, Syed A. Latif, David J. Morris, Matthew P. Hardy, and Renshan Ge