The Population Council’s Center for Biomedical Research (CBR) is a vibrant hub of scientific investigation and product development. Our scientists address critical questions in reproductive health and develop innovative products that protect the health and well-being of millions of people worldwide. CBR is located at Rockefeller University in New York City.

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Submissions from 2014

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Differential effects of c-Src and c-Yes on the endocytic vesicle-mediated trafficking events at the Sertoli cell blood-testis barrier: An in vitro study, Xiang Xiao, Dolores D. Mruk, Elissa W.P. Wong, Will M. Lee, Daishu Han, Chris K.C. Wong, and C. Yan Cheng

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Efficacy of the selective progesterone receptor agonist Nestorone for chronic experimental autoimmune encephalomyelitis, Laura Garay, Maria Claudia Gonzalez Deniselle, Régine Sitruk-Ware, Rachida Guennoun, Michael Schumacher, and Alejandro De Nicola

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Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins, Xiang Xiao, Dolores D. Mruk, Elizabeth I. Tang, Chris K.C. Wong, Will M. Lee, Constance M. John, Paul J. Turek, Bruno Silvestrini, and C. Yan Cheng

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Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques, Mayla Hsu, Brandon F. Keele, Meropi Aravantinou, Noa Krawczyk, Samantha Seidor, Ciby J. Abraham, Shimin Zhang, Aixa Rodriguez, Larisa Kizima, Nina Derby, Ninochka Jean-Pierre, Olga Mizenina, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, José Fernández-Romero, Thomas Zydowsky, and Melissa Robbiani

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Ezrin is an actin binding protein that regulates Sertoli cell and spermatid adhesion during spermatogenesis, N. Ece Gungor-Ordueri, Elizabeth I. Tang, Ciler Celik-Ozenci, and C. Yan Cheng

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Fascin 1 is an actin filament-bundling protein that regulates ectoplasmic specialization dynamics in the rat testis, N. Ece Gungor-Ordueri, Ciler Celik-Ozenci, and C. Yan Cheng

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First-in-human safety and pharmacokinetics (PK) of a MIV-150/zinc acetate/carrageenan gel (PC-1005), George W. Creasy, Craig Hoesley, Barbara Friedland, Shimin Zhang, Marlena Gehret Plagianos, Kyle Kleinbeck, Keith Levendosky, José Fernández-Romero, and Thomas Zydowsky

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Germ cell transport across the seminiferous epithelium during spermatogenesis, Xiang Xiao, Dolores D. Mruk, Chris K.C. Wong, and C. Yan Cheng

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HSV-2-driven increase in the expression of α_4β_7 correlates with increased susceptibility to vaginal SHIV_SF162P3 infection, Diana J. Goode, Rosaline Truong, Guillermo Villegas, Giulia Calenda, Natalia Guerra-Perez, Michael Piatak Jr., Jeffrey D. Lifson, James Blanchard, Agegnehu Gettie, Melissa Robbiani, and Elena Martinelli

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Intercellular adhesion molecule 1: Recent findings and new concepts involved in mammalian spermatogenesis, Dolores D. Mruk, Xiang Xiao, Marta Lydka, Michelle W.M. Li, Barbara Bilinska, and C. Yan Cheng

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In vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition, Aixa Rodriguez, Kyle Kleinbeck, Olga Mizenina, Larisa Kizima, Keith Levendosky, Ninochka Jean-Pierre, Guillermo Villegas, Brian E. Ford, Michael Cooney, Natalia Teleshova, Melissa Robbiani, Betsy C. Herold, Thomas Zydowsky, and José Fernández-Romero

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Microbicidas para la prevención de infecciones de transmisión sexual: estado actual y estrategias para la evaluación preclínica de nuevos candidatos, José Fernández-Romero, Pedro I. Gil, Viviana Re, Melissa Robbiani, and Gabriela Paglini

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MIV-150-containing intravaginal rings protect macaque vaginal explants against SHIV-RT infection, Louise Ouattara, Patrick Barnable, Paul Mawson, Samantha Seidor, Thomas Zydowsky, Larisa Kizima, Aixa Rodriguez, José Fernández-Romero, Michael Cooney, Kevin Roberts, Agegnehu Gettie, James Blanchard, Melissa Robbiani, and Natalia Teleshova

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MZC and 1% TFV gel: Multipurpose prevention approaches, Ninochka Jean-Pierre, Patrick Barnable, Larisa Kizima, Aixa Rodriguez, Samantha Seidor, Meredith R. Clark, Gustavo F. Doncel, Melissa Robbiani, Thomas Zydowsky, Natalia Teleshova, and José Fernández-Romero

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New insights into FAK function and regulation during spermatogenesis, N. Ece Gungor-Ordueri, Dolores D. Mruk, Hin Ting Wan, Elissa W.P. Wong, Ciler Celik-Ozenci, Pearl P.Y. Lie, and C. Yan Cheng

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N-WASP is required for structural integrity of the blood-testis barrier, Xiang Xiao, Dolores D. Mruk, Elizabeth I. Tang, R'ada Massarwa, Ka-Wai Mok, Nan Li, Chris K.C. Wong, Will M. Lee, Scott B. Snapper, Ben-Zion Shilo, Eyal D. Schejter, and C. Yan Cheng

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p204-initiated innate antiviral response in mouse Leydig cells, Weiwei Zhu, Peng Liu, Lili Yu, Qiaoyuan Chen, Zhenghui Liu, Keqin Yan, Will M. Lee, C. Yan Cheng, and Daishu Han

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Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr^407: An in vitro study, Hin Ting Wan, Dolores D. Mruk, Chris K.C. Wong, and C. Yan Cheng

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Revisiting the roles of progesterone and allopregnanolone in the nervous system: Resurgence of the progesterone receptors, Michael Schumacher, Claudia Mattern, Abdel M. Ghoumari, J.P. Oudinet, Florencia Labombarda, Régine Sitruk-Ware, Alejandro De Nicola, and Rachida Guennoun

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Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis, H.T. Wan, Dolores D. Mruk, Elizabeth I. Tang, Xiang Xiao, Yan Ho Cheng, Elissa W.P. Wong, Chris K.C. Wong, and C. Yan Cheng

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rpS6 regulates blood–testis barrier dynamics through Akt-mediated effects on MMP-9, Ka-Wai Mok, Dolores D. Mruk, and C. Yan Cheng

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Sertolin mediates blood-testis barrier restructuring, Michelle W.M. Li, C. Yan Cheng, and Dolores D. Mruk

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Sex hormones selectively impact the endocervical mucosal microenvironment: Implications for HIV transmission, Diana J. Goode, Meropi Aravantinou, Sebastian Jarl, Rosaline Truong, Nina Derby, Natalia Guerra-Perez, Jessica Kenney, James Blanchard, Agegnehu Gettie, Melissa Robbiani, and Elena Martinelli

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Short communication: A repeated simian human immunodeficiency virus reverse transcriptase/herpes simplex virus type 2 cochallenge macaque model for the evaluation of microbicides, Jessica Kenney, Nina Derby, Meropi Aravantinou, Kyle Kleinbeck, Ines Frank, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, Thomas Zydowsky, and Melissa Robbiani

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The free perinatal/postpartum contraceptive services project for migrant women in Shanghai: Effects on the incidence of unintended pregnancy, Yong-mei Huang, Ruth Merkatz, Hao-ping Zhu, Kevin Roberts, Régine Sitruk-Ware, Li-nan Cheng, and The Perinatal/Postpartum Contraceptive Services Project for Migrant Women Study Group

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Thyroid hormone function in the rat testis, Ying Gao, Will M. Lee, and C. Yan Cheng

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Vaginal expression of efflux transporters and the potential impact on the disposition of microbicides in vitro and in rabbits, Carolien Grammen, Myriam Baes, Steven Haenen, Jasper Verguts, Koen Augustyns, Thomas Zydowsky, Paolo La Colla, Patrick Augustijns, and Joachim Brouwers

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Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis, Qing Wen, Qiao-Song Zheng, Xi-Xia Li, Zhao-Yuan Hu, Fei Gao, C. Yan Cheng, and Yi-Xun Liu

Submissions from 2013

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7a-methyl-19-nortestosterone (MENT®): The Population Council's contribution to research on male contraception and treatment of hypogonadism, Eberhard Nieschlag, Narender Kumar, and Régine Sitruk-Ware

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Actin cross-linking protein palladin and spermatogenesis, Xiao-jing Qian, Dolores D. Mruk, Yan Ho Cheng, and C. Yan Cheng

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Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation, Jiaxiang Shao, Tengyuan Liu, Qian Reuben Xie, Tingting Zhang, Hemei Yu, Boshi Wang, Weihai Ying, Dolores D. Mruk, Bruno Silvestrini, C. Yan Cheng, and Weiliang Xia

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Adjudin disrupts spermatogenesis by targeting drug transporters: Lesson from the breast cancer resistance protein (BCRP), Xiao-jing Qian, Yan Ho Cheng, Pranitha Jenardhanan, Dolores D. Mruk, Premendu P. Mathur, Weiliang Xia, Bruno Silvestrini, and C. Yan Cheng

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A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo, Jessica Kenney; Aixa Rodriguez; Larisa Kizima; Samantha Seidor; Radhika Menon; Ninochka Jean-Pierre; Pavel Pugach; Keith Levendosky; Nina Derby; Agegnehu Gettie; James Blanchard; Michael Piatak, Jr.; Jeffrey D. Lifson; Gabriela Paglini; Thomas Zydowsky; Melissa Robbiani; and José Fernández-Romero

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Breast cancer resistance protein (Bcrp) and the testis—An unexpected turn of events, Xiao-jing Qian, Yan Ho Cheng, Dolores D. Mruk, and C. Yan Cheng

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Breast cancer resistance protein regulates apical ectoplasmic specialization dynamics stage specifically in the rat testis, Xiao-jing Qian, Dolores D. Mruk, Elissa W.P. Wong, and C. Yan Cheng

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Characteristics and metabolic effects of estrogen and progestins contained in oral contraceptive pills, Régine Sitruk-Ware and Anita Nath

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Characteristics associated with suppression of spermatogenesis in a male hormonal contraceptive trial using testosterone and Nestorone® gels, Mara Y. Roth, Niloufar Ilani, Christina Wang, Stephanie T. Page, William J. Bremner, Ronald S. Swerdloff, Clint Dart, Régine Sitruk-Ware, Narender Kumar, Diana Blithe, and John K. Amory

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Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors, Axel Mann, Nikolas Friedrich, Anders Krarup, Jacqueline Weber, Emanuel Stiegeler, Birgit Dreier, Pavel Pugach, Melissa Robbiani, Tina Riedel, Kerstin Moehle, John A. Robinson, Peter Rusert, Andreas Pluckthun, and Alexandra Trkola

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Contraception technology: Past, present and future, Régine Sitruk-Ware; Anita Nath; and Daniel R. Mishell, Jr.

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c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood–testis barrier axis via its effects on protein recruitment and distribution, Xiang Xiao, Dolores D. Mruk, and C. Yan Cheng

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Focal adhesion kinase and actin regulatory/binding proteins that modulate F-actin organization at the tissue barrier: Lesson from the testis, C. Yan Cheng, Pearl P.Y. Lie, Elissa W.P. Wong, and Dolores D. Mruk

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Focal adhesion kinase is a regulator of F-actin dynamics: New insights from studies in the testis, Stephen Y.T. Li, Dolores D. Mruk, and C. Yan Cheng

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Germ cells contribute to the function of the Sertoli cell barrier: An in vitro study, Linlin Su, Ilona A. Kopera-Sobota, Barbara Bilinska, C. Yan Cheng, and Dolores D. Mruk

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Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humans, Kun Li, Ya Ni, Yi He, Wen-Ying Chen, Jian-Xin Lu, C. Yan Cheng, Renshan Ge, and Qi-Xian Shi

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In search of the optimal delivery method for anti-HIV microbicides: Are intravaginal rings the way forward?, Nina Derby, Thomas Zydowsky, and Melissa Robbiani

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Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat, Xiang Xiao, C. Yan Cheng, and Dolores D. Mruk

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Intercellular adhesion molecules (ICAMs) and spermatogenesis, Xiang Xiao, Dolores D. Mruk, and C. Yan Cheng

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Male contraceptive Adjudin is a potential anti-cancer drug, Qian Reuben Xie, Yewei Liu, Jiaxiang Shao, Jian Yang, Tengyuan Liu, Tingting Zhang, Boshi Wang, Dolores D. Mruk, Bruno Silvestrini, C. Yan Cheng, and Weiliang Xia

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MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis, Elizabeth I. Tang and Dolores D. Mruk

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NC1 domain of collagen α3(IV) derived from the basement membrane regulates Sertoli cell blood-testis barrier dynamics, Elissa W.P. Wong and C. Yan Cheng

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New vision for contraceptive research and development, Régine Sitruk-Ware and Peter J. Donaldson

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Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes, Xiao-jing Qian, Dolores D. Mruk, Elissa W.P. Wong, Pearl P.Y. Lie, and C. Yan Cheng

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p-FAK-Tyr^397 regulates spermatid adhesion in the rat testis via its effects on F-actin organization at the ectoplasmic specialization, Hin Ting Wan, Dolores D. Mruk, Stephen Y.T. Li, Ka-Wai Mok, Will M. Lee, Chris K.C. Wong, and C. Yan Cheng

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Progesterone and related progestins: Potential new health benefits, Régine Sitruk-Ware and Martine El-Etr

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RAI14 (retinoic acid induced protein 14) is an F-actin regulator—Lesson from the testis, Xiao-jing Qian, Dolores D. Mruk, Yan Ho Cheng, and C. Yan Cheng

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Rai14 (Retinoic Acid Induced Protein 14) is involved in regulating F-Actin dynamics at the ectoplasmic specialization in the rat testis, Xiao-jing Qian, Dolores D. Mruk, and C. Yan Cheng

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Regulation of actin dynamics and protein trafficking during spermatogenesis—Insights into a complex process, Wenhui Su, Dolores D. Mruk, and C. Yan Cheng

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Regulation of blood–testis barrier (BTB) dynamics during spermatogenesis via the 'yin' and 'yang' effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2, Ka-Wai Mok, Dolores D. Mruk, and C. Yan Cheng

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Rictor/mTORC2 regulates blood-testis barrier dynamics via its effects on gap junction communications and actin filament network, Ka-Wai Mok, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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Safety and adherence of a non-medicated intravaginal ring (IVR) (MTN-005), Population Council

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Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex, Elissa W.P. Wong, Will M. Lee, and C. Yan Cheng

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Signalling pathways regulating the blood–testis barrier, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk

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Simian immunodeficiency virus interactions with macaque dendritic cells, Natalia Teleshova, Nina Derby, Elena Martinelli, Pavel Pugach, Giulia Calenda, and Melissa Robbiani

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Spermatogenesis, Mammals, C. Yan Cheng and Dolores D. Mruk

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Statement on combined hormonal contraceptives containing third- or fourth-generation progestogens or cyproterone acetate, and the associated risk of thromboembolism, Johannes Bitzer, Jean-Jacques Amy, Rob Beerthuizen, Martin Birkhauser, Teresa Bombas, Mitchell Creinin, Philip Darney, Lisa Ferreira Vicente, Kristina Gemzell-Danielsson, Bruno Imthurn, Jeffrey T. Jensen, Andrew M. Kaunitz, Ali Kubba, Medard M. Lech, Diana Mansour, Gabriele Merki, Thomas Rabe, Katrina Sedlecki, David Serfaty, Jacques Seydoux, Lee P. Shulman, Régine Sitruk-Ware, Sven O. Skouby, Anne Szarewski, James Trussell, and Carolyn Westhoff

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Targeting testis-specific proteins to inhibit spermatogenesis: Lesson from endocrine disrupting chemicals, Hin Ting Wan, Dolores D. Mruk, Chris K.C. Wong, and C. Yan Cheng

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The apical ES–BTB–BM functional axis is an emerging target for toxicant-induced infertility, Hin Ting Wan, Dolores D. Mruk, Chris K.C. Wong, and C. Yan Cheng

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The frequency of α4β7high memory CD4+ T cells correlates with susceptibility to rectal simian immunodeficiency virus infection, Elena Martinelli; Filippo Veglia; Diana J. Goode; Natalia Guerra-Perez; Meropi Aravantinou; James Arthos; Michael Piatak, Jr.; Jeffrey D. Lifson; James Blanchard; Agegnehu Gettie; and Melissa Robbiani

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The neural androgen receptor: A therapeutic target for myelin repair in chronic demyelination, Rashad Hussain, Abdel M. Ghoumari, Bartosz Bielecki, Jerome Steibel, Nelly Boehm, Philippe Liere, Wendy B. Macklin, Narender Kumar, Rene Habert, Sakina Mhaouty-Kodja, Francois Tronche, Régine Sitruk-Ware, Michael Schumacher, and M. Said Ghandour

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Ulipristal blocks ovulation by inhibiting progesterone receptor-dependent pathways intrinsic to the ovary, Shanmugasundaram Nallasamy, Jaeyeon Kim, Régine Sitruk-Ware, Milan K. Bagchi, and Indrani C. Bagchi

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Why do we need male contraceptives?, C. Yan Cheng and Dolores D. Mruk

Submissions from 2012

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A new combination of testosterone and nestorone transdermal gels for male hormonal contraception, Niloufar Ilani, Mara Y. Roth, John K. Amory, Ronald S. Swerdloff, Clint Dart, Stephanie T. Page, William J. Bremner, Régine Sitruk-Ware, Narender Kumar, Diana Blithe, and Christina Wang

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An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaques, Rachel Singer, Paul Mawson, Nina Derby, Aixa Rodriguez, Larisa Kizima, Radhika Menon, Daniel Goldman, Jessica Kenney, Meropi Aravantinou, Samantha Seidor, Agegnehu Gettie, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, José Fernández-Romero, Melissa Robbiani, and Thomas Zydowsky

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A peptide derived from laminin-γ3 reversibly impairs spermatogenesis in rats, Linlin Su, Dolores D. Mruk, Pearl P.Y. Lie, Bruno Silvestrini, and C. Yan Cheng

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A single dose of a MIV-150/zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use, Jessica Kenney, Rachel Singer, Nina Derby, Meropi Aravantinou, Ciby J. Abraham, Radhika Menon, Samantha Seidor, Shimin Zhang, Agegnehu Gettie, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, José Fernández-Romero, Thomas Zydowsky, and Melissa Robbiani

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Characterization of peripheral and mucosal immune responses in rhesus macaques on long-term tenofovir and emtricitabine combination antiretroviral therapy, Edith Jasny, Suzanne Geer, Ines Frank, Panagiotis Vagenas, Meropi Aravantinou, Andres M. Salazar, Jeffrey D. Lifson, Michael Piatak Jr., Agegnehu Gettie, James L. Blanchard, and Melissa Robbiani

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Drug transporters in spermatogenesis: A re-evaluation of recent data on P-glycoprotein, Dolores D. Mruk and C. Yan Cheng

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Effects of a novel estrogen-free, progesterone receptor modulator-contraceptive vaginal ring on inhibition of ovulation, bleeding patterns and endometrium in normal women, Vivian Brache; Régine Sitruk-Ware; A. Williams; Diana Blithe; Horacio B. Croxatto; Narender Kumar; Sushma Kumar; Yun-yen Tsong; Irving Sivin; Anita Nath; Heather Sussman; Leila Cochon; Marie-José Miranda; Veronica Reyes; Anibal Faundes; and Daniel R. Mishell, Jr.

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Filamin A: A regulator of blood-testis barrier assembly during post-natal development, Wenhui Su, Dolores D. Mruk, and C. Yan Cheng

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Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis, Wenhui Su, Dolores D. Mruk, Pearl P.Y. Lie, Wing-Yee Lui, and C. Yan Cheng

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Focal adhesion kinase-Tyr^407 and -Tyr^397 exhibit antagonistic effects on blood–testis barrier dynamics in the rat, Pearl P.Y. Lie, Dolores D. Mruk, Ka-Wai Mok, Linlin Su, Will M. Lee, and C. Yan Cheng

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Increased impact of a contraceptive vaginal ring with ethinyl estradiol and nestorone on C-reactive protein, Mandana Rad, Jacobus Burggraaf, Régine Sitruk-Ware, Marieke L. de Kam, Adam F. Cohen, and Cornelius Kluft

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In search of suitable in vitro models to study germ cell movement across the blood-testis barrier, Dolores D. Mruk and C. Yan Cheng

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Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis, Elizabeth I. Tang, Xiang Xiao, Dolores D. Mruk, Xiao-jing Qian, Ka-Wai Mok, Pranitha Jenardhanan, Will M. Lee, Premendu P. Mathur, and C. Yan Cheng

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Non-specific microbicide development: Then and now, Joseph W. Romano, Melissa Robbiani, Gustavo F. Doncel, and Thomas Moench

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Postpartum unintended pregnancy and contraception practice among rural-to-urban migrant women in Shanghai, Yong-mei Huang, Ruth Merkatz, Jian-Zhong Kang, Kevin Roberts, Xiao-Yu Hu, Francis Di Donato, Régine Sitruk-Ware, and Li-nan Cheng

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Progesterone receptors: A key for neuroprotection in experimental stroke, Ailing Liu, Isabelle Margaill, Shaodong Zhang, Florencia Labombarda, Berard Coqueran, Brigitte Delespierre, Philippe Liere, Catherine Marchand-Leroux, Bert W. O'Malley, John P. Lydon, Alejandro De Nicola, Régine Sitruk-Ware, Claudia Mattern, Michel Plotkine, Michael Schumacher, and Rachida Guennoun

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Regulation of drug transporters in the testis by environmental toxicant cadmium, steroids and cytokines, Linlin Su, Dolores D. Mruk, and C. Yan Cheng

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Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor, Linlin Su, Dolores D. Mruk, and C. Yan Cheng

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rpS6 regulates blood–testis barrier dynamics by affecting F-actin organization and protein recruitment, Ka-Wai Mok, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng

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Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility, Ka-Wai Mok, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

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The biology of interleukin-1: Emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk

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The blood–testis barrier and its implications for male contraception, C. Yan Cheng and Dolores D. Mruk

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The nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT infection, Meropi Aravantinou, Rachel Singer, Nina Derby, Giulia Calenda, Paul Mawson, Ciby J. Abraham, Radhika Menon, Samantha Seidor, Daniel Goldman, Jessica Kenney, Guillermo Villegas, Agegnehu Gettie, James Blanchard, Jeffrey D. Lifson, Michael Piatak Jr., José Fernández-Romero, Thomas Zydowsky, Natalia Teleshova, and Melissa Robbiani

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The Scribble/Lgl/Dlg polarity protein complex is a regulator of blood–testis barrier dynamics and spermatid polarity during spermatogenesis, Wenhui Su, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng

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Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton, Marta Lydka, Barbara Bilinska, C. Yan Cheng, and Dolores D. Mruk

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Vasectomy reversal in humans, Aaron M. Bernie, E. Charles Osterberg, Peter J. Stahl, Ranjith Ramasamy, and Marc Goldstein

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Zinc acetate/carrageenan gels exhibit potent activity in vivo against high dose HSV-2 vaginal and rectal challenge, José Fernández-Romero, Ciby J. Abraham, Aixa Rodriguez, Larisa Kizima, Ninochka Jean-Pierre, Radhika Menon, Othell Begay, Samantha Seidor, Brian E. Ford, Pedro I. Gil, Jennifer Peters, David Katz, Melissa Robbiani, and Thomas Zydowsky

Submissions from 2011

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7 α-methyl-19-nortestosterone vs. testosterone implants for hypogonadal osteoporosis: A preclinical study in the aged male orchidectomized rat model, M. Sinnesael, F. Callewaert, M. Morreels, Narender Kumar, Régine Sitruk-Ware, K. van Proeyen, P. Hespel, Steven Boonen, F. Claessens, and Dirk Vanderschueren

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Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis, Michelle W.M. Li, Xiang Xiao, Dolores D. Mruk, Yee-ling Lam, Will M. Lee, Wing-Yee Lui, Michele Bonanomi, Bruno Silvestrini, and C. Yan Cheng