Microneedle of drug delivery systems
Document Type
Chapter
Publication Date
6-18-2024
Abstract
Over the past few years, there has been significant interest in a developing transdermal delivery technology due to its ability to effectively deliver therapeutic and cosmeceutical products for various purposes. These applications include vaccines, drugs, and biomolecules aimed at addressing skin-related issues. One major advantage of transdermal administration is its ability to bypass the initial metabolic breakdown of the drug and facilitate sustained release. However, the stratum corneum acts as a barrier, limiting drug delivery. To overcome this challenge, microneedles (MNs) have emerged as a painless, minimally invasive, and user-friendly transdermal drug delivery system, offering high drug bioavailability. In recent years, various types of MNs have been developed using innovative production techniques. These MNs can be classified morphologically as solid, coated, dissolved, or hollow, depending on the specific transdermal drug delivery method employed, namely “poke and patch,” “coat and poke,” “poke and release,” and “poke and flow,” respectively.
Recommended Citation
Damiri, Fouad, Hitendra M. Patel, Sagar Salave, K. Bharathi, Nagavendra Kommineni, B. H. Jaswanth Gowda, Karthika Paul, Sanju Bala Dhull, and Mohammed Berrada. 2024. "Microneedle of drug delivery systems," in Nanoscience and Nanotechnology for Smart Prevention, Diagnostics and Therapeutics: Fundamentals to Applications (pp. 243–260), https://doi.org/10.1002/9781394175222.ch10.
DOI
10.1002/9781394175222.ch10
Language
English
https://doi.org/10.1002/9781394175222.ch10