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Submissions from 2005
Regulation of sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/β-catenin (CATNB) signaling pathway: An in vitro and in vivo study, Nikki P.Y. Lee, Dolores D. Mruk, Ching-hang Wong, and C. Yan Cheng
Regulation of sertoli-germ cell adherens junction dynamics via changes in protein-protein interactions of the N-cadherin-β-catenin protein complex which are possibly mediated by c-Src and myotubularin-related protein 2: An in vivo study using an androgen suppression model, Jiayi Zhang, Ching-hang Wong, Weiliang Xia, Dolores D. Mruk, Nikki P.Y. Lee, Will M. Lee, and C. Yan Cheng
Sertoli cell expression of steroidogenic acute regulatory protein-related lipid transfer 1 and 5 domain-containing proteins and sterol regulatory element binding protein-1 are interleukin-1 regulated by activation of c-Jun N-terminal kinase and cyclooxygenase-2 and cytokine induction, Tomomoto Ishikawa, KeumSil Hwang, Deborah Lazzarino, and Patricia L. Morris
Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases, Michelle K.Y. Siu, Ching-hang Wong, Will M. Lee, and C. Yan Cheng
Serum Nestorone® and ethinyl estradiol levels, and ovulation inhibition in women using three different dosage combinations of a Nestorone progestogen-ethinyl estradiol contraceptive vaginal ring on a bleeding-signaled regimen, Ian S. Fraser, Edith Weisberg, Vivian Brache, Francisco Alvarez, Rebeca Massai, Daniel R. Mishell Jr., Dan Apter, Judi Gale, Yun-yen Tsong, and Irving Sivin
Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated, Renshan Ge, Qiang Dong, Chantal M. Sottas, Syed A. Latif, David J. Morris, and Matthew P. Hardy
Stress hormone and male reproductive function, Matthew P. Hardy, Hui-Bao Gao, Qiang Dong, Renshan Ge, Qian Wang, Wei Ran Chai, Xing Feng, and Chantal M. Sottas
Testicular expression of small ubiquitin-related modifier-1 (SUMO-1) supports multiple roles in spermatogenesis: Silencing of sex chromosomes in spermatocytes, spermatid microtubule nucleation, and nuclear reshaping, Margarita Vigodner and Patricia L. Morris
TGF-β3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study, Weiliang Xia and C. Yan Cheng
The blood-testis barrier: Its biology, regulation, and physiological role in spermatogenesis, Ching-hang Wong and C. Yan Cheng
The levonorgestrel intrauterine system: Long-term contraception and therapeutic effects, Régine Sitruk-Ware and Pirjo Inki
The Sept4 septin locus is required for sperm terminal differentiation in mice, Holger Kissel, Maria-Magdalena Georgescu, Sarit Larisch, Katia Manova, Gary R. Hunnicutt, and Hermann Steller
Vaginal delivery of contraceptives, Régine Sitruk-Ware
α2-Macroglobulin expression in the liver in response to inflammation is mediated by the testis, Wing-Yee Lui, Yan Ho Cheng, Dolores D. Mruk, Chin Ho Cheng, Meng-Yun Mo, Will M. Lee, and C. Yan Cheng
Submissions from 2004
Adaptors, junction dynamics, and spermatogenesis, Nikki P.Y. Lee and C. Yan Cheng
Assay for establishing whether microbicide applicators have been exposed to the vagina, Andrea R. Wallace, Mitchell Thorn, Robin A. Maguire, Kristin M. Sudol, and David M. Phillips
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue, Qinxue Hu, Ines Frank, Vennansha G. Williams, John J. Santos, Patricia Watts, George E. Griffin, John P. Moore, Melissa Robbiani, and Robin J. Shattock
Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone β subunit in mouse gonadotrope cells, Daniel J. Bernard
Cell-cell interactions at the ectoplasmic specialization in the testis, Dolores D. Mruk and C. Yan Cheng
Cloning and characterization of rat spermatid protein SSP411: A thioredoxin-like protein, Hui-Juan Shi, Ai Zhen Wu, Michelle Santos, Zong-Ming Feng, Li Huang, Yong-Mei Chen, Kai Zhu, and Ching-Ling C. Chen
Cloning of a novel inhibin alpha cDNA from rhesus monkey testis, Daniel J. Bernard, Teresa K. Woodruff, and Tony M. Plant
CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-γ-secreting simian immunodeficiency virus-specific T cells, Natalia Teleshova, Jessica Kenney, Jennifer Jones, Jason Marshall, Gary Van Nest, Jason Dufour, Rudolf Bohm, Jeffrey D. Lifson, Agegnehu Gettie, and Melissa Robbiani
Development of Leydig cells in the insulin-like growth factor-I (IGF-I) knockout mouse: Effects of IGF-I replacement and gonadotropic stimulation, Gui-Min Wang and Matthew P. Hardy
Disruption of Mtmr2 CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis, Alessandra Bolino, Annalisa Bolis, Stefano Carlo Previtali, Giorgia Dina, Simona Bussini, Gabriele Dati, Stefano Amadio, Ubaldo Del Carro, Dolores D. Mruk, Maria Laura Feltri, C. Yan Cheng, Angelo Quattrini, and Lawrence Wrabetz
Dynamic cross-talk between cells and the extracellular matrix in the testis, Michelle K.Y. Siu and C. Yan Cheng
Ectoplasmic specialization, a testis-specific cell-cell actin-based adherens junction type: Is this a potential target for male contraceptive development?, Nikki P.Y. Lee and C. Yan Cheng
Effect of chenodeoxycholic acid on 11β-hydroxysteroid dehydrogenase in various target tissues, David J. Morris, Graham W. Souness, Syed A. Latif, Matthew P. Hardy, and Andrew S. Brem
Exogenous progestagens and the human breast, Régine Sitruk-Ware and Genevieve Plu-Bureau
Extracellular matrix: Recent advances on its role in junction dynamics in the seminiferous epithelium during spermatogenesis, Michelle K.Y. Siu and C. Yan Cheng
Future developments in hormonal contraception, Elof D.B. Johansson
Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells, Stuart G. Turville, John J. Santos, Ines Frank, Paul U. Cameron, John Wilkinson, Monica Miranda-Saksena, Joanne Dable, Hella Stoessel, Nikolaus Romani, Michael Piatak Jr., Jeffrey D. Lifson, Melissa Robbiani, and Anthony L. Cunningham
Induction of neutralising antibodies restricts the use of human granulocyte/macrophage colony stimulating factor for vaccine studies in rhesus macaques, Martin Eisenblätter, Christiane Stahl-Hennig, Seraphin Kuate, Nicole Stolte, Edith Jasny, Helmut Hahn, Melissa Robbiani, Klara Tenner-Racz, Paul Racz, Ralph M. Steinman, Klaus Uberla, and Ralf Ignatius
Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells, Benson T. Akingbemi, Chantal M. Sottas, Anna I. Koulova, Gary R. Klinefelter, and Matthew P. Hardy
Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis, Michelle K.Y. Siu and C. Yan Cheng
Lubricants containing N-9 may enhance rectal transmission of HIV and other STIs, David M. Phillips, Kristin M. Sudol, Clark L. Taylor, Laura Guichard, Robert Elsen, and Robin A. Maguire
Macaque dendritic cells infected with SIV-recombinant canarypox ex vivo induce SIV-specific immune responses in vivo, Loreley Villamide-Herrera, Ralf Ignatius, Michael A. Eller, Kelly Wilkinson, Catherine Griffin, Erin Mehlhop, Jennifer Jones, Seol-Young Han, Mark G. Lewis, Stephanie Parrish, Tom C. VanCott, Jeffrey D. Lifson, Sarah Schlesinger, John R. Mascola, and Melissa Robbiani
Mifepristone does not induce cervical softening in non-pregnant women, Avraham Ben-Chetrit, Talia Eldar-Geva, Tzina Lindenberg, Morshed Farhat, Shlomo Shimonovitz, David Zacut, Hadassa Gelber, Régine Sitruk-Ware, and Irving M. Spitz
Müllerian-inhibiting substance inhibits rat Leydig cell regeneration after ethylene dimethanesulphonate ablation, Antonio Salva, Matthew P. Hardy, Xiu-feng Wu, Chantal M. Sottas, David T. MacLaughlin, Patricia K. Donahoe, and Mary M. Lee
New delivery systems in contraception: Vaginal rings, Elof D.B. Johansson and Régine Sitruk-Ware
New progestogens: A review of their effects in perimenopausal and postmenopausal women, Régine Sitruk-Ware
Nitric oxide/nitric oxide synthase, spermatogenesis, and tight junction dynamics, Nikki P.Y. Lee and C. Yan Cheng
Patent: Androgen as a male contraceptive and non-contraceptive androgen replacement, Alfred J. Moo-Young
Pharmacological profile of progestins, Régine Sitruk-Ware
Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances, Benson T. Akingbemi, Renshan Ge, Gary R. Klinefelter, and Matthew P. Hardy
Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress, Qiang Dong, Antonio Salva, Chantal M. Sottas, Enmei Niu, Michael Holmes, and Matthew P. Hardy
Regulation of blood-testis barrier dynamics: An in vivo study, Ching-hang Wong, Dolores D. Mruk, Wing-Yee Lui, and C. Yan Cheng
Relative safety of sexual lubricants for rectal intercourse, Kristin M. Sudol and David M. Phillips
Release-modulating factors strongly affecting steroid diffusion from silicone elastomer, Harold A. Nash, Dale N. Robertson, and Simone J. Evans
Sertoli-sertoli and sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis, Dolores D. Mruk and C. Yan Cheng
Short-term Flt3L treatment effectively mobilizes functional macaque dendritic cells, Natalia Teleshova, Jennifer Jones, Jessica Kenney, Jeanette Purcell, Rudolf Bohm, Agegnehu Gettie, and Melissa Robbiani
Two-year performance of a Nestorone®-releasing contraceptive implant: A three-center study of 300 women, Irving Sivin, Horacio B. Croxatto, Luis Bahamondes, Vivian Brache, Francisco Alvarez-Sanchez, Rebeca Massai, Janet Schechter, Sirpa Ranta, Narender Kumar, Esther Wu, Ana-Sofia Tejeda, Veronica Reyes, Elaine Travers, Arthur Allen, and Alfred J. Moo-Young
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis, Nikki P.Y. Lee, Dolores D. Mruk, Anne M. Conway, and C. Yan Cheng
Submissions from 2003
A clinical trial of 7α-methyl-19-nortestosterone implants for possible use as a long-acting contraceptive for men, Sigrid von Eckardstein, Gabriela Noe, Vivian Brache, Eberhard Nieschlag, Horacio B. Croxatto, Francisco Alvarez-Sanchez, Alfred J. Moo-Young, Irving Sivin, Narender Kumar, Margaret Small, and Kalyan Sundaram
Adherens junction dynamics in the testis and spermatogenesis, Wing-Yee Lui, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Adhering junction dynamics in the testis are regulated by an interplay of β1-integrin and focal adhesion complex-associated proteins, Michelle K.Y. Siu, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
A role for kit receptor signaling in Leydig cell steroidogenesis, Gerson Rothschild, Chantal M. Sottas, Holger Kissel, Valter Agosti, Katia Manova, Matthew P. Hardy, and Peter Besmer
Carrageenan formulation prevents macrophage trafficking from vagina: Implications for microbicide development, Maria-Elisa Perotti, Alessia Pirovano, and David M. Phillips
Dendritic cells as a conduit to improve HIV vaccines, Melissa Robbiani
Effects of insulin-like growth factor I on steroidogenic enzyme expression levels in mouse Leydig cells, Gui-Min Wang, Peter J. O'Shaughnessy, Curtis Chubb, Bernard Robaire, and Matthew P. Hardy
Effects of levonorgestrel-releasing intra-uterine system on the expression of vascular endothelial growth factor and adrenomedullin in the endometrium in adenomyosis, Jovelle B. Laoag-Fernandez, Takeshi Maruo, Paivi Pakarinen, Irving M. Spitz, and Elof D.B. Johansson
Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types, Thomas J. Ketas, Per Johan Klasse, Catherine Spenlehauer, Mirjana Nesin, Ines Frank, Melissa Robbiani, Julie M. Strizki, Gregory R. Reyes, Bahige M. Baroudy, and John P. Moore
Estradiol-progesterone interaction during the preparation of vaginal rings, Saleh I. Saleh, Sayed H. Khidr, Sayed M. Ahmed, Theodore M. Jackanicz, and Harold A. Nash
Estradiol/progesterone-releasing vaginal rings for hormone replacement therapy in postmenopausal women, Anna Lissa Hamada, Takeshi Maruo, Takashi Samoto, Shigeki Yoshida, Harold A. Nash, Irving M. Spitz, and Elof D.B. Johansson
Estrogen receptor-α gene deficiency enhances androgen biosynthesis in the mouse Leydig cell, Benson T. Akingbemi, Renshan Ge, Cheryl S. Rosenfeld, Leslie G. Newton, Dianne O. Hardy, James F. Catterall, Dennis B. Lubahn, Kenneth S. Korach, and Matthew P. Hardy
Evidence for tissue selectivity of the synthetic androgen 7α-methyl-19-nortestosterone in hypogonadal men, Richard A. Anderson, A. Michael Wallace, Naveed Sattar, Narendar Kumar, and Kalyan Sundaram
Fer kinase/FerT and adherens junction dynamics in the testis: An in vitro and in vivo study, Yong-Mei Chen, Nikki P.Y. Lee, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Gestational exposure to ethane dimethanesulfonate permanently alters reproductive competence in the CD-1 mouse, Dana K. Tarka-Leeds, Juan D. Suarez, Naomi L. Roberts, John M. Rogers, Matthew P. Hardy, and Gary R. Klinefelter
Human genital epithelial cells capture cell-free human immunodeficiency virus type 1 and transmit the virus to CD4+ cells: Implications for mechanisms of sexual transmission, Zhiwei Wu, Zhiwei Chen, and David M. Phillips
Human immunodeficiency virus type 1 attachment, coreceptor, and fusion inhibitors are active against both direct and trans infection of primary cells, Thomas J. Ketas, Ines Frank, Per Johan Klasse, Brian M. Sullivan, Jason P. Gardner, Catherine Spenlehauer, Mirjana Nesin, William C. Olson, John P. Moore, and Melissa Robbiani
Immunodeficiency virus exploitation of dendritic cells in the early steps of infection, Natalia Teleshova, Ines Frank, and Melissa Robbiani
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?, Nikki P.Y. Lee, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Mechanisms of glucocorticoid-induced Leydig cell apoptosis, Hui-Bao Gao, Ming-Han Tong, Yan-Qin Hu, Hai-Yan You, Qiang-Su Guo, Renshan Ge, and Matthew P. Hardy
Nestorone®: Clinical applications for contraception and HRT, Régine Sitruk-Ware, Margaret Small, Narender Kumar, Yun-yen Tsong, Kalyan Sundaram, and Theodore M. Jackanicz
Normal reproductive function in InhBP/p120-deficient mice, Daniel J. Bernard, Kathleen H. Burns, Bisong Haupt, Martin M. Matzuk, and Teresa K. Woodruff
Pharmacological properties of mifepristone: Toxicology and safety in animal and human studies, Régine Sitruk-Ware and Irving M. Spitz
Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses, Ines Frank, John J. Santos, Erin Mehlhop, Loreley Villamide-Herrera, Christine Santisteban, Agegnehu Gettie, Ralf Ignatius, Jeffrey D. Lifson, and Melissa Robbiani
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120, Ronald S. Veazey, Robin J. Shattock, Melissa Robbiani, J. Christian Kirijan, Jennifer Jones, Qinxue Hu, Thomas J. Ketas, Preston A. Marx, Per Johan Klasse, Dennis R. Burton, and John P. Moore
Progestins in hormonal therapy (HT) today, tomorrow and the next day: A roundtable discussion, Régine Sitruk-Ware
Prostaglandin (PG) FP and EP1 receptors mediate PGF2α and PGE2 regulation of interleukin-1β expression in Leydig cell progenitors, Laurence Walch, Emanuela Clavarino, and Patricia L. Morris
Rab8B GTPase and junction dynamics in the testis, Ann S.N. Lau and Dolores D. Mruk
Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3′,5′-cyclic guanosine monophosphate/protein kinase G signaling pathway: An in vitro study, Nikki P.Y. Lee and C. Yan Cheng
Rho GTPases and spermatogenesis, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
Risks and benefits, advantages and disadvantages of levonorgestrel-releasing contraceptive implants, Irving Sivin
Role of tissue inhibitor of metalloproteases-1 in junction dynamics in the testis, Dolores D. Mruk, Michelle K.Y. Siu, Anne M. Conway, Nikki P.Y. Lee, Ann S.N. Lau, and C. Yan Cheng
Sertoli cell tight junction dynamics: Their regulation during spermatogenesis, Wing-Yee Lui, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Sertoli-germ cell adherens junction dynamics in the testis are regulated by RhoB GTPase via the ROCK/LIMK signaling pathway, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
Subdermal progestin implant (Nestorone®) in the treatment of endometriosis: Clinical response to various doses, Kaija Ylänen, Timo Laatikainen, Pekka Lähteenmäki, and Alfred J. Moo-Young
TGF-β3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: An in vivo study, Wing-Yee Lui, Daria C.H. Wong, Dolores D. Mruk, and C. Yan Cheng
TGF-βs: Their role in testicular function and Sertoli cell tight junction dynamics, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
The functional roles of 11β-HSD1: Vascular tissue, testis and brain, David J. Morris, Andrew S. Brem, Renshan Ge, P. Harry Jellinck, Randall R. Sakai, and Matthew P. Hardy
The interplay of collagen IV, tumor necrosis factor-α, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates sertoli cell-tight junction dynamics in the rat testis, Michelle K.Y. Siu, Will M. Lee, and C. Yan Cheng
Transforming growth factor β3 regulates the dynamics of sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway, Wing-Yee Lui, Will M. Lee, and C. Yan Cheng
Transmission, acute HIV-1 infection and the quest for strategies to prevent infection, Melissa Robbiani and Ashley T. Haase
Submissions from 2002
Jadelle® levonorgestrel rod implants: A summary of scientific data and lessons learned from programmatic experience, Irving Sivin, Harold A. Nash, and Sandra N. Waldman
Submissions from 2000
Patent: Silicone core long term androgen delivery implant, Alfred J. Moo-Young and Saleh I. Saleh
Submissions from 1999
Patent: Intravaginal rings with insertable drug-containing core, Saleh I. Saleh, Harold A. Nash, C. Wayne Bardin, and Troy Harmon
Patent: Progesterone vaginal ring for treatment of infertility, Theodore M. Jackanicz, Horacio B. Croxatto, Leopoldo Glasser Drexler, and Fernando Zegers-Hochschild
Submissions from 1998
Patent: Male contraceptive implant, Alfred J. Moo-Young and Saleh I. Saleh
Patent: Method of preparation of ester derivatives of steroids, Fang Li
Submissions from 1997
Patent: Isolated DNA molecule encoding SPRM-1 protein, Bogi Andersen, Richard V. Pearse, Peter N. Schlegel, Michael G. Rosenfeld, and C. Wayne Bardin