Submissions from 2013
Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation, Jiaxiang Shao, Tengyuan Liu, Qian Reuben Xie, Tingting Zhang, Hemei Yu, Boshi Wang, Weihai Ying, Dolores D. Mruk, Bruno Silvestrini, C. Yan Cheng, and Weiliang Xia
Progesterone and related progestins: Potential new health benefits, Régine Sitruk-Ware and Martine El-Etr
Characteristics and metabolic effects of estrogen and progestins contained in oral contraceptive pills, Régine Sitruk-Ware and Anita Nath
The blood-follicle barrier (BFB) in disease and in ovarian function, Michelle K.Y. Siu and C. Yan Cheng
Role of P-glycoprotein at the blood-testis barrier on adjudin distribution in the testis a revisit of recent data, Linlin Su, Pranitha Jenardhanan, Dolores D. Mruk, Premendu P. Mathur, Yan Ho Cheng, Ka-Wai Mok, Michele Bonanomi, Bruno Silvestrini, and C. Yan Cheng
Germ cells contribute to the function of the Sertoli cell barrier: An in vitro study, Linlin Su, Ilona A. Kopera-Sobota, Barbara Bilinska, C. Yan Cheng, and Dolores D. Mruk
Regulation of actin dynamics and protein trafficking during spermatogenesis—Insights into a complex process, Wenhui Su, Dolores D. Mruk, and C. Yan Cheng
Polarity protein complex scribble/lgl/dlg and epithelial cell barriers, Wen Hui Su, Dolores D. Mruk, Elissa W.P. Wong, Wing-Yee Lui, and C. Yan Cheng
MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis, Elizabeth I. Tang and Dolores D. Mruk
p-FAK-Tyr^397 regulates spermatid adhesion in the rat testis via its effects on F-actin organization at the ectoplasmic specialization, Hin Ting Wan, Dolores D. Mruk, Stephen Y.T. Li, Ka-Wai Mok, Will M. Lee, Chris K.C. Wong, and C. Yan Cheng
Targeting testis-specific proteins to inhibit spermatogenesis: Lesson from endocrine disrupting chemicals, Hin Ting Wan, Dolores D. Mruk, Chris K.C. Wong, and C. Yan Cheng
The apical ES–BTB–BM functional axis is an emerging target for toxicant-induced infertility, Hin Ting Wan, Dolores D. Mruk, Chris K.C. Wong, and C. Yan Cheng
NC1 domain of collagen α3(IV) derived from the basement membrane regulates Sertoli cell blood-testis barrier dynamics, Elissa W.P. Wong and C. Yan Cheng
Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex, Elissa W.P. Wong, Will M. Lee, and C. Yan Cheng
Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat, Xiang Xiao, C. Yan Cheng, and Dolores D. Mruk
c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood–testis barrier axis via its effects on protein recruitment and distribution, Xiang Xiao, Dolores D. Mruk, and C. Yan Cheng
Intercellular adhesion molecules (ICAMs) and spermatogenesis, Xiang Xiao, Dolores D. Mruk, and C. Yan Cheng
C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics, Xiang Xiao, Dolores D. Mruk, Faith L. Cheng, and C. Yan Cheng
Nonreceptor protein kinases c-Src, c-Yes, and FAK are biomarkers for male contraceptive research, Xiang Xiao, Dolores D. Mruk, Pranitha Jenardhanan, Jayakanthan Mannu, Premendu P. Mathur, Will M. Lee, Bruno Silvestrini, Yan Ho Cheng, and C. Yan Cheng
Male contraceptive Adjudin is a potential anti-cancer drug, Qian Reuben Xie, Yewei Liu, Jiaxiang Shao, Jian Yang, Tengyuan Liu, Tingting Zhang, Boshi Wang, Dolores D. Mruk, Bruno Silvestrini, C. Yan Cheng, and Weiliang Xia
Submissions from 2012
Vasectomy reversal in humans, Aaron M. Bernie, E. Charles Osterberg, Peter J. Stahl, Ranjith Ramasamy, and Marc Goldstein
Effects of a novel estrogen-free, progesterone receptor modulator-contraceptive vaginal ring on inhibition of ovulation, bleeding patterns and endometrium in normal women, Vivian Brache; Régine Sitruk-Ware; A. Williams; Diana Blithe; Horacio B. Croxatto; Narender Kumar; Sushma Kumar; Yun-yen Tsong; Irving Sivin; Anita Nath; Heather Sussman; Leila Cochon; Marie-José Miranda; Veronica Reyes; Anibal Faundes; and Daniel R. Mishell, Jr.
The blood–testis barrier and its implications for male contraception, C. Yan Cheng and Dolores D. Mruk
A new combination of testosterone and nestorone transdermal gels for male hormonal contraception, Niloufar Ilani, Mara Y. Roth, John K. Amory, Ronald S. Swerdloff, Clint Dart, Stephanie T. Page, William J. Bremner, Régine Sitruk-Ware, Narender Kumar, Diana Blithe, and Christina Wang
The biology of interleukin-1: Emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk
Focal adhesion kinase-Tyr^407 and -Tyr^397 exhibit antagonistic effects on blood–testis barrier dynamics in the rat, Pearl P.Y. Lie, Dolores D. Mruk, Ka-Wai Mok, Linlin Su, Will M. Lee, and C. Yan Cheng
Progesterone receptors: A key for neuroprotection in experimental stroke, Ailing Liu, Isabelle Margaill, Shaodong Zhang, Florencia Labombarda, Berard Coqueran, Brigitte Delespierre, Philippe Liere, Catherine Marchand-Leroux, Bert W. O'Malley, John P. Lydon, Alejandro De Nicola, Régine Sitruk-Ware, Claudia Mattern, Michel Plotkine, Michael Schumacher, and Rachida Guennoun
Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton, Marta Lydka, Barbara Bilinska, C. Yan Cheng, and Dolores D. Mruk
Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility, Ka-Wai Mok, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
rpS6 regulates blood–testis barrier dynamics by affecting F-actin organization and protein recruitment, Ka-Wai Mok, Dolores D. Mruk, Bruno Silvestrini, and C. Yan Cheng
Drug transporters in spermatogenesis: A re-evaluation of recent data on P-glycoprotein, Dolores D. Mruk and C. Yan Cheng
In search of suitable in vitro models to study germ cell movement across the blood-testis barrier, Dolores D. Mruk and C. Yan Cheng
Increased impact of a contraceptive vaginal ring with ethinyl estradiol and nestorone on C-reactive protein, Mandana Rad, Jacobus Burggraaf, Régine Sitruk-Ware, Marieke L. de Kam, Adam F. Cohen, and Cornelius Kluft
Regulation of drug transporters in the testis by environmental toxicant cadmium, steroids and cytokines, Linlin Su, Dolores D. Mruk, and C. Yan Cheng
Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor, Linlin Su, Dolores D. Mruk, and C. Yan Cheng
A peptide derived from laminin-γ3 reversibly impairs spermatogenesis in rats, Linlin Su, Dolores D. Mruk, Pearl P.Y. Lie, Bruno Silvestrini, and C. Yan Cheng
Filamin A: A regulator of blood-testis barrier assembly during post-natal development, Wenhui Su, Dolores D. Mruk, and C. Yan Cheng
Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis, Wenhui Su, Dolores D. Mruk, Pearl P.Y. Lie, Wing-Yee Lui, and C. Yan Cheng
The Scribble/Lgl/Dlg polarity protein complex is a regulator of blood–testis barrier dynamics and spermatid polarity during spermatogenesis, Wenhui Su, Elissa W.P. Wong, Dolores D. Mruk, and C. Yan Cheng
Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis, Elizabeth I. Tang, Xiang Xiao, Dolores D. Mruk, Xiao-jing Qian, Ka-Wai Mok, Pranitha Jenardhanan, Will M. Lee, Premendu P. Mathur, and C. Yan Cheng
Intercellular adhesion molecule-1 is a regulator of blood-testis barrier function, Xiang Xiao, C. Yan Cheng, and Dolores D. Mruk
Submissions from 2011
Interactions of laminin β3 fragment with β1-integrin receptor: A revisit of the apical ectoplasmic specialization-blood–testis-barrier-hemidesmosome functional axis in the testis, C. Yan Cheng, Pearl P.Y. Lie, Ka-Wai Mok, Yan Ho Cheng, Elissa W.P. Wong, Jayakanthan Mannu, Premendu P. Mathur, Helen H.N. Yan, and Dolores D. Mruk
Adjudin disrupts spermatogenesis via the action of some unlikely partners: Eps8, Arp2/3 complex, drebrin E, PAR6 and 14-3-3, C. Yan Cheng, Pearl P.Y. Lie, Elissa W.P. Wong, Dolores D. Mruk, and Bruno Silvestrini
Actin binding proteins and spermiogenesis: Some unexpected findings, C. Yan Cheng and Dolores D. Mruk
Male contraception: Where do we go from here?, C. Yan Cheng and Dolores D. Mruk
Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: Novel insights from studies on Eps8 and Arp3, C. Yan Cheng and Dolores D. Mruk
Regulation of blood–testis barrier dynamics by desmosome, gap junction, hemidesmosome and polarity proteins: An unexpected turn of events, C. Yan Cheng, Elissa W.P. Wong, Pearl P.Y. Lie, Michelle W.M. Li, Dolores D. Mruk, Helen H.N. Yan, Ka-Wai Mok, Jayakanthan Mannu, Premendu P. Mathur, Wing-Yee Lui, Will M. Lee, Michele Bonanomi, and Bruno Silvestrini
Environmental toxicants and male reproductive function, C. Yan Cheng, Elissa W.P. Wong, Pearl P.Y. Lie, Michelle W.M. Li, Linlin Su, Erica R. Siu, Helen H.N. Yan, J. Mannu, Premendu P. Mathur, Michele Bonanomi, Bruno Silvestrini, and Dolores D. Mruk
Polarity proteins and actin regulatory proteins are unlikely partners that regulate cell adhesion in the seminiferous epithelium during spermatogenesis, C. Yan Cheng, Elissa W.P. Wong, Pearl P.Y. Lie, Dolores D. Mruk, Xiang Xiao, Michelle W.M. Li, Wing Yee Lui, and Will M. Lee
Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis, Yan Ho Cheng, Elissa W.P. Wong, and C. Yan Cheng
Characterization and functionality of proliferative human sertoli cells, Kitty Chui, Alpa Trivedi, C. Yan Cheng, Diana B. Cherbavaz, Paul F. Dazin, Ai Lam Thu Huynh, James B. Mitchell, Gabriel A. Rabinovich, Linda J. Noble-Haeusslein, and Constance M. John
Effects of methoxychlor and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase-3 activities in human and rat testes, Guo-Xin Hu, Binghai Zhao, Yanhui Chu, X.H. Li, Benson T. Akingbemi, Zhi-Qiang Zheng, and Renshan Ge
Differential nuclear receptor and gene expression in human endometrial adenocarcinoma cells: Regulation by a novel selective progesterone receptor modulator, KeumSil Hwang, Lyann Mitchell, Catherine Rapelje, and Patricia L. Morris
Role of 11β-OH-C_19 and C_21 steroids in the coupling of 11β-HSD1 and 17β-HSD3 in regulation of testosterone biosynthesis in rat Leydig cells, Syed A. Latif, Mae Shen, Renshan Ge, Chantal M. Sottas, Matthew P. Hardy, and David J. Morris
Interleukin-1α is a regulator of the blood-testis barrier, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk
The biology of the desmosome-like junction: A versatile anchoring junction and signal transducer in the seminiferous epithelium, Pearl P.Y. Lie, C. Yan Cheng, and Dolores D. Mruk
Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis, Michelle W.M. Li, Xiang Xiao, Dolores D. Mruk, Yee-ling Lam, Will M. Lee, Wing-Yee Lui, Michele Bonanomi, Bruno Silvestrini, and C. Yan Cheng
Environmental inhibitors of 11β-hydroxysteroid dehydrogenase type 2, Xue Ma, Qing-Quan Lian, Qiang Dong, and Renshan Ge
A study to assess the assembly of a functional blood–testis barrier in developing rat testes, Ka-Wai Mok, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes, Ka-Wai Mok, Dolores D. Mruk, Pearl P.Y. Lie, Wing Yee Lui, and C. Yan Cheng
An in vitro system to study sertoli cell blood-testis barrier dynamics, Dolores D. Mruk and C. Yan Cheng
Desmosomes in the testis: Moving into an unchartered territory, Dolores D. Mruk and C. Yan Cheng
Enhanced chemiluminescence (ECL) for routine immunoblotting. An inexpensive alternative to commercially available kits, Dolores D. Mruk and C. Yan Cheng
Environmental contaminants: Is male reproductive health at risk?, Dolores D. Mruk and C. Yan Cheng
Testin and actin are key molecular targets of adjudin, an anti-spermatogenic agent, in the testis, Dolores D. Mruk and C. Yan Cheng
The myotubularin family of lipid phosphatases in disease and in spermatogenesis, Dolores D. Mruk and C. Yan Cheng
Emerging role for drug transporters at the blood-testis barrier, Dolores D. Mruk, Linlin Su, and C. Yan Cheng
The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes, Michelle K.Y. Siu, Ching-hang Wong, Weiliang Xia, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Drug transporters, the blood–testis barrier, and spermatogenesis, Linlin Su, Dolores D. Mruk, and C. Yan Cheng
Drug transporters and blood–testis barrier function, Linlin Su, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
P-glycoprotein regulates blood–testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK), Linlin Su, Dolores D. Mruk, Wing Yee Lui, Will M. Lee, and C. Yan Chen
Impacts of environmental toxicants on male reproductive dysfunction, Elissa W.P. Wong and C. Yan Cheng
c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes, Xiang Xiao, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
The inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 by perfluoroalkylated substances, Binghai Zhao, Qing-Quan Lian, Yanhui Chu, Dianne O. Hardy, Xiao-Kun Li, and Renshan Ge
Submissions from 2010
Intrauterine administration of CDB-2914 (Ulipristal) suppresses the endometrium of rhesus macaques, Robert M. Brenner, Ov D. Slayden, Anita Nath, Yun-yen Tsong, and Régine Sitruk-Ware
A local autocrine axis in the testes that regulates spermatogenesis, C. Yan Cheng and Dolores D. Mruk
New frontiers in nonhormonal male contraception, C. Yan Cheng and Dolores D. Mruk
New frontiers in nonhormonal male contraception, C. Yan Cheng and Dolores D. Mruk
The biology of spermatogenesis: The past, present and future, C. Yan Cheng and Dolores D. Mruk
Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: New insights and advances, C. Yan Cheng, Elissa W.P. Wong, Helen H.N. Yan, and Dolores D. Mruk
Perinatal exposure to di-(2-ethylhexyl) phthalate leads to restricted growth and delayed lung maturation in newborn rats, Shang-Qin Chen, Jin-Ni Chen, Xiao-Hong Cai, Guo-Rong Chen, Yuan Gao, Renshan Ge, Hai-Shan Wu, Zhen-Lang Lin, and Jing Lin
7α-hydroxytestosterone affects 11β-hydroxysteroid dehydrogenase 1 direction in rat leydig cells, Guo-Xin Hu, Qing-Quan Lian, Bing-Bing Chen, Pramod Vishwanath Prasad, Narender Kumar, Zhi-Qiang Zheng, and Renshan Ge
Deletion of the Igf1 gene: Suppressive effects on adult Leydig cell development, Guo-Xin Hu, Han Lin, Guo-Rong Chen, Bing-Bing Chen, Qing-Quan Lian, Dianne O. Hardy, Barry R. Zirkin, and Renshan Ge
The annulus of the mouse sperm tail is required to establish a membrane diffusion barrier that is engaged during the late steps of spermiogenesis, Susanna Kwitny, Angela V. Klaus, and Gary R. Hunnicutt
Restricted Arp3 expression in the testis prevents blood–testis barrier disruption during junction restructuring at spermatogenesis, Pearl P.Y. Lie, Apple Y.N. Chan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Cytoskeletal dynamics and spermatogenesis, Pearl P.Y. Lie, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Connexin 43 is critical to maintain the homeostasis of the blood–testis barrier via its effects on tight junction reassembly, Michelle W.M. Li, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Clinically relevant progestins regulate neurogenic and neuroprotective responses in vitro and in vivo, Lifei Liu, Liqin Zhao, Hongyun She, Shuhua Chen, Jun Ming Wang, Charisse Wong, Kelsey McClure, Régine Sitruk-Ware, and Roberta Diaz Brinton
Claudin and occludin expression and function in the seminiferous epithelium, Carla M.K. Morrow, Dolores D. Mruk, C. Yan Cheng, and R. A. Hess
Tight junctions in the testis: New perspectives, Dolores D. Mruk and C. Y. Cheng
Endometrial effect of progesterone delivered by vaginal rings in estrogen-treated postmenopausal women, Gabriela Noe; Régine Sitruk-Ware; Fernando Zegers-Hochschild; Bruce Variano; Juan Carlos Montero; P. Arriagada; A. Li; Frank Z. Stanczyk; J.C. Felix; Daniel R. Mishell, Jr.; and Horacio B. Croxatto
No-needle local anesthesia for adult male circumcision, Yifeng Peng, Puneet Masson, Philip S. Li, Yue Chang, Long Tian, Richard Lee, Howard H. Kim, David C. Sokal, and Marc Goldstein
Single-dose Pharmacokinetics of Nestorone®, a potential female-contraceptive, Pramod Vishwanath Prasad, Mohammad Bashir, Régine Sitruk-Ware, and Narender Kumar
Sertoli-germ cell junctions in the testis: A review of recent data, Ilona A. Ropera, Barbara Bilinska, C. Yan Cheng, and Dolores D. Mruk
The use of newer progestins for contraception, Régine Sitruk-Ware and Anita Nath
The use of newer progestins for contraception, Régine Sitruk-Ware and Anita Nath
Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo, Linlin Su, C. Yan Cheng, and Dolores D. Mruk
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood–testis barrier, Linlin Su, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Regulation of blood–testis barrier dynamics by TGF-β3 is a Cdc42-dependent protein trafficking event, Elissa W.P. Wong, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng
Inhibition of LH-stimulated androgen production in rat immature Leydig cells: Effects on nuclear receptor steroidogenic factor 1 by FGF2, Ye-Chen Xiao, Dianne O. Hardy, Chantal M. Sottas, Xiao-Kun Li, and Renshan Ge