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Submissions from 2024

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Risk factors for and outcomes of ring expulsions with a one year contraceptive vaginal system, Marlena Gehret Plagianos, Shaalini Ramanadhan, Ruth Merkatz, Vivian Brache, Barbara Friedland, and Lisa Haddad

Submissions from 2023

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Center for Biomedical Research at the Population Council, Population Council

Submissions from 2022

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Nestorone nanosuspension-loaded dissolving microneedles array patch: A promising novel approach for “on-demand” hormonal female-controlled peritcoital contraception, Ebru Altuntaş, Ismaiel A. Tekko, Lalitkumar K. Vora, Narender Kumar, Rebecca Brodsky, Olivier Chevallier, Emma McAlister, Qonita Kurnia Anjani, Helen O. McCarthy, and Ryan F. Donnelly

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Measuring potential interest in a postpartum contraceptive vaginal ring among breastfeeding women in India, Lorna Begg, James Sailer, Avishek Hazra, Malabika Roy, Ruth Merkatz, Lisa Haddad, Rebecca Brodsky, and John Bongaarts

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Recap of the Sixth International Symposium on Intrauterine Devices and Systems for Women's Health, Rachel Ferat, Lisa Haddad, Carolyn Westhoff, and David Hubacher

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Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): A prospective cohort study protocol, Lisa Haddad, Gina Bailey Herring, C. Christina Mehta, Tyree Staple, Marisa R. Young, Sakthivel Govindaraj, Vijayakumar Velu, and Alicia K. Smith

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Husbands’ concerns and experiences with the progesterone vaginal ring in three sub-Saharan African countries: A mixed methods study, Francis Obare Onyango, Fatou Mbow, Saumya RamaRao, and Avishek Hazra

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What have we learned? Implementation of a shared learning agenda and access strategy for the hormonal intrauterine device, Kate Rademacher, Tabitha Sripipatana, Kendal Danna, Deborah Sitrin, Aurélie Brunie, Katie M. Williams, Kayode Afolabi, Francia Rasoanirina, Saumya RamaRao, Anne Pfitzer, Devon Cain, Morgan Simon, Elaine Menotti, Anna Hazelwood, Anthony Adindu Nwala, Zainab Saidu, Raveena Chowdhury, Anne Taiwo, Agnes Chidanyika, Gathari Ndirangu, Markus J. Steiner, Marie Chantale Lepine, Rick Homan, Abdulmumin Saad, John Vivalo, and Laneta J. Dorflinger

Submissions from 2021

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Griffithsin and carrageenan combination results in antiviral synergy against SARS-CoV-1 and 2 in a pseudoviral model, Sahar Alsaidi, Nadjet Cornejal, Oneil Mahoney, Claudia Melo, Neeharika Verma, Thierry Bonnaire, Theresa Chang, Barry R. O'Keefe, James Sailer, Thomas Zydowsky, Natalia Teleshova, and José Fernández-Romero

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Polymorphism characterization of segesterone acetate: A comprehensive study using XRPD, FT-IR and Raman spectroscopy, Fermin F.H. Aragon, Clement M. Haeck, Paulo C. Morais, and Bruce Variano

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Estimating the market size for a dual prevention pill: Adding contraception to pre-exposure prophylaxis (PrEP) to increase uptake, Lorna Begg, Rebecca Brodsky, Barbara Friedland, Sanyukta Mathur, James Sailer, and George W. Creasy

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Pharmacodynamics and pharmacokinetics of a copper intrauterine contraceptive system releasing ulipristal acetate: A randomized proof-of-concept study, Vivian Brache, Carolina Sales Vieira, Marlena Gehret Plagianos, Maud Lansiaux, Ruth Merkatz, Heather Sussman, Leila Cochon, Ana-Sofia Tejada, Narender Kumar, Dan Loeven, Diana Blithe, Abi Santhosh Aprem, Alistair Williams, Athilakshmi Kannan, Indrani C. Bagchi, and Régine Sitruk-Ware

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Harnessing the power of partnership to advance reproductive health and rights, Julia Bunting and Régine Sitruk-Ware

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The vaginal microbiota, bacterial biofilms and polymeric drug-releasing vaginal rings, Louise Carson, Ruth Merkatz, Elena Martinelli, Peter Boyd, Bruce Variano, Teresa Sallent, and R. Karl Malcolm

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Algal and cyanobacterial lectins and their antimicrobial properties, José Fernández-Romero, Maria Gabriela Paglini, Christine Priano, Adolfina Koroch, Yoel Rodriguez, James Sailer, and Natalia Teleshova

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The promise of the dual prevention pill: A framework for development and introduction, Barbara Friedland, Sanyukta Mathur, and Lisa Haddad

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Addressing contraceptive needs exacerbated by COVID-19: A call for increasing choice and access to self-managed methods, Lisa Haddad, Saumya RamaRao, Avishek Hazra, Harriet Birungi, and James Sailer

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Contraceptive technologies: Looking ahead to new approaches to increase options for family planning, Lisa Haddad, John Townsend, and Régine Sitruk-Ware

Programs increasing access to IUDs and IUSs in the USA and in lower- and middle-income countries (LMIC), Anna Hazelwood, Ricky Lu, Tessa Madden, Anita Makins, Susan Ontiri, Caitlin Quade, Kate Rademacher, James Sailer, and Tabitha Sripipatana

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Segesterone acetate serum levels with a regression model of continuous use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system, James Liu, Marlena Gehret Plagianos, David F. Archer, James A. Simon, Andrew M. Kaunitz, Shelli Graham, Brian Bernick, and Sebastian Mirkin

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Contraception au futur: Nouvelles techniques à l’horizon de la prochaine décennie, Régine Sitruk-Ware

Submissions from 2020

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The ins and outs of drug-releasing vaginal rings: A literature review of expulsions and removals, Peter Boyd, Ruth Merkatz, Bruce Variano, and R. Karl Malcolm

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Dose-finding study of a 90-day contraceptive vaginal ring releasing estradiol and segesterone acetate, Melissa J. Chen, Mitchell Creinin, David K. Turok, David F. Archer, Kurt T. Barnhart, Carolyn Westhoff, Michael A. Thomas, Jeffrey T. Jensen, Bruce Variano, Régine Sitruk-Ware, Anita Shanker, Jill Long, and Diana Blithe

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Editorial: The 6th International IUD Symposium, David Hubacher, James Sailer, Carolyn Westhoff, and IUD Symposium Organizing Committee

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The benefits and limitations of donating new contraceptive technology: The case of the International Contraceptive Access (ICA) Foundation and the LNG IUS Program in Brazil, Laura Miranda, John Townsend, Anibal Faundes, and Luis Bahamondes

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ICA Foundation supports LNG IUS access in low- and middle-income countries, Population Council

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The Population Council's Center for Biomedical Research: A nonprofit product-development entity, Population Council

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Infographic—Getting to market: Roadmap for user access, Saumya RamaRao, Wilson Liambila, Fatou Mbow, and Avishek Hazra

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Progesterone vaginal ring as a new contraceptive option for lactating mothers: Evidence from a multicenter non-randomized comparative clinical trial in India, Malabika Roy, Avishek Hazra, Ruth Merkatz, Marlena Gehret Plagianos, Mohcine Alami, L.N. Gaur, Kumudha Aruldas, Heather Sussman, Bruce Variano, and Régine Sitruk-Ware

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Commentary on research to improve contraceptive and multipurpose prevention technologies, J. Joseph Speidel, John Townsend, Elspeth Williams, Jamie Quam, and Kirsten M.J. Thompson

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Contraceptive technologies for global health: Ethically getting to safe, effective and acceptable options for women and men, John Townsend, Régine Sitruk-Ware, Saumya RamaRao, and James Sailer

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Choosing and using the progesterone vaginal ring: Women’s lived experiences in three African cities, Chi-Chi Undie, Saumya RamaRao, and Fatou Mbow

Submissions from 2019

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Combined Nestorone–testosterone gel suppresses serum gonadotropins to concentrations associated with effective hormonal contraception in men, Bradley D. Anawalt, Mara Y. Roth, Jonas Ceponis, Vijaya Surampadi, John K. Amory, Ronald S. Swerdloff, Peter Y. Liu, Clint Dart, William J. Bremner, Régine Sitruk-Ware, Narender Kumar, Diana Blithe, Stephanie T. Page, and Christina Wang

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Efficacy of the 1-year (13-cycle) segesterone acetate and ethinylestradiol contraceptive vaginal system: Results of two multicentre, open-label, single-arm, phase 3 trials, David F. Archer, Ruth Merkatz, Luis Bahamondes, Carolyn Westhoff, Philip Darney, Dan Apter, Jeffrey T. Jensen, Vivian Brache, Anita L. Nelson, Erika Banks, György Bártfai, David J. Portman, Marlena Gehret Plagianos, Clint Dart, Narender Kumar, George W. Creasy, Régine Sitruk-Ware, and Diana Blithe

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In vitro release testing methods for drug-releasing vaginal rings, Peter Boyd, Bruce Variano, Patrick Spence, Clare F. McCoy, Diarmaid J. Murphy, Yahya H. Dallal Bashi, and R. Karl Malcolm

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Topical formulations to prevent sexually transmitted infections: Are we on track?, José Fernández-Romero, Maria Gabriela Paglini, and Thomas Zydowsky

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Segesterone acetate/ethinyl estradiol 12-month contraceptive vaginal system safety evaluation, Kristina Gemzell-Danielsson, Régine Sitruk-Ware, Mitchell Creinin, Michael Thomas, Kurt T. Barnhart, George W. Creasy, Heather Sussman, Mohcine Alami, Anne E. Burke, Edith Weisberg, Ian S. Fraser, Marie-José Miranda, Melissa Gilliam, James Liu, Bruce R. Carr, Marlena Gehret Plagianos, Kevin Roberts, and Diana Blithe

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Efficacy and safety of a 1-year segesterone acetate and ethinyl estradiol contraceptive vaginal system, Ruth Merkatz, Maureen Magnani, Heather Sussman, George W. Creasy, and Régine Sitruk-Ware

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Post-use ring weight and residual drug content as potential objective measures of user adherence to a contraceptive progesterone vaginal ring, Diarmaid J. Murphy, Clare F. McCoy, Marlena Gehret Plagianos, Saumya RamaRao, Ruth Merkatz, Heather Clark, Peter Boyd, Bruce Variano, and R. Karl Malcolm

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Factors influencing satisfaction with oral contraceptive pills and injectables among past users in Kenya, George Odwe, Joyce Mumah, Francis Obare, Marylene Wamukoya, Kazuyo Machiyama, John C. Cleland, and John B. Casterline

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Contraception and public health ethics, Saumya RamaRao and John Townsend

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Bone turnover markers in women participating in a dose-finding trial of a contraceptive vaginal ring releasing Nestorone and estradiol, Molly Tiedeken, Carolyn Westhoff, Adi Cohen, Serge Cremers, Régine Sitruk-Ware, Diana Blithe, and The NICHD Contraceptive Trials Network Vaginal Ring Group

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Bleeding profile associated with 1-year use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system: Pooled analysis from phase 3 trials, Carolina Sales Vieira, Ian S. Fraser, Marlena Gehret Plagianos, Anne E. Burke, Carolyn Westhoff, Jeffrey T. Jensen, Vivian Brache, Luis Bahamondes, Ruth Merkatz, Régine Sitruk-Ware, and Diana Blithe

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Preventing secondary exposure to women from men applying a novel Nestorone/testosterone contraceptive gel, F. Yuen, S. Wu, A. Thirumalai, Ronald S. Swerdloff, Stephanie T. Page, Peter Y. Liu, Clint Dart, H. Wu, Diana Blithe, Régine Sitruk-Ware, J. Long, F. Bai, L. Hull, William J. Bremner, Bradley D. Anawalt, and Christina Wang

Submissions from 2018

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Feasibility of patent and proprietary medicine vendor provision of injectable contraceptives: Preliminary results from implementation science research in Oyo and Nasarawa, Nigeria, Sara Chace Dwyer, Salisu Mohammed Ishaku, Faizah Okunade, Laura Reichenbach, and Aparna Jain

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Introducing the progesterone vaginal ring (PVR) as a new option for postpartum family planning in sub-Saharan Africa: Insights from engagements with stakeholders, Salisu Mohammed Ishaku, Nafissatou Diop, Babacar Mane, Wilson Liambila, Saumya RamaRao, Heather Clark, Harriet Birungi, Godwin Unumeri, and Francis Obare

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Continuous dosing of a novel contraceptive vaginal ring releasing Nestorone® and estradiol: Pharmacokinetics from a dose-finding study, Jeffrey T. Jensen, Alison E. Edelman, Beatrice A. Chen, D.F. Archer, Kurt T. Barnhart, M.A. Thomas, Anne E. Burke, Carolyn Westhoff, Livia Wan, Régine Sitruk-Ware, Narender Kumar, Bruce Variano, and Diana Blithe

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Solid state ^13C NMR spectroscopy provides direct evidence for reaction between ethinyl estradiol and a silicone elastomer vaginal ring drug delivery system, Clare F. McCoy, David C. Apperley, Bruce Variano, Heather Sussman, Dan Loeven, Peter Boyd, and R. Karl Malcolm

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Introduction of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) injectable contraception at facility and community levels: Pilot results from 4 districts of Uganda, George Odwe, Kate Gray, Annet Kyarimpa, Francis Obare, and Grace Nagendi

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Patent: Combination product for the prevention of sexually transmitted infections, Barry R. O'Keefe, Melissa Robbiani, and José Fernández-Romero

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Do women find the progesterone vaginal ring acceptable? Findings from Kenya, Nigeria, and Senegal, Saumya RamaRao, Francis Obare, Salisu Mohammed Ishaku, Babacar Mane, Heather Clark, Wilson Liambila, Godwin Unumeri, Harriet Birungi, Nafissatou Diop, Deepa Rajamani, and John Townsend

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Effects of concurrent vaginal miconazole treatment on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol delivered from a contraceptive vaginal ring: A randomized, crossover drug–drug interaction study, Katharine B. Simmons, Narender Kumar, Marlena Gehret Plagianos, Kevin Roberts, Elena Hoskin, Leo Han, Mohcine Alami, George W. Creasy, Bruce Variano, and Ruth Merkatz

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Non-clinical studies of progesterone, Régine Sitruk-Ware

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Patent: Neuroprotection and myelin repair using Nestorone.RTM, Régine Sitruk-Ware, Michael Schumacher, Maria Helmut, Roberta Brinton, Martine El-Etr, Abdelmouman Ghoumari, and Rachida Guennoun

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Factors associated with non-adherence to instructions for using the Nestorone®/ethinyl estradiol contraceptive vaginal ring, Bianca M. Stifani, Marlena Gehret Plagianos, Carolina Sales Vieira, and Ruth Merkatz

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Dynamics of injectable contraceptive use in India, The Evidence Project

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Dynamics of oral contraceptive pill use in India, The Evidence Project

Submissions from 2017

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MZC gel inhibits SHIV-RT and HSV-2 in macaque vaginal mucosa and SHIV-RT in rectal mucosa, Giulia Calenda, Guillermo Villegas, Patrick Barnable, Claudia Litterst, Keith Levendosky, Agegnehu Gettie, Michael Cooney, James Blanchard, José Fernández-Romero, Thomas Zydowsky, and Natalia Teleshova

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An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques, Nina Derby, Meropi Aravantinou, Jessica Kenney, Shweta Ugaonkar, Asa Wesenberg, Jolanta Wilk, Larisa Kizima, Aixa Rodriguez, Shimin Zhang, Olga Mizenina, Keith Levendosky, Michael Cooney, Samantha Seidor, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael Piatak Jr., Jeffrey D. Lifson, José Fernández-Romero, Thomas Zydowsky, and Melissa Robbiani

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Nestorone® (NES) a novel progestin for non-oral contraception: Structure-activity relationships and brain metabolism studies, Narender Kumar, Jerome Fagart, Philippe Liere, Scott J. Mitchell, Alanah R. Knibb, Isabelle Petit-Topin, Marion Rame, Martine El-Etr, Michael Schumacher, Jeremy J. Lambert, Marie-Edith Rafestin-Oblin, and Régine Sitruk-Ware

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What do users really want?, Saumya RamaRao, John Townsend, and James Sailer

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Use of male methods of contraception worldwide, John Ross and Karen Hardee

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Patent: Nestorone®/estradiol transdermal gel, Régine Sitruk-Ware, Dario Norberto Ramon Carrara, and Arnaud Grenier

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Factors predicting improper use of a woman-controlled long-acting reversible contraceptive: Results from the acceptability study of a novel contraceptive vaginal ring, Bianca M. Stifani, Marlena Gehret Plagianos, Carolina Sales Vieira, and Ruth Merkatz

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Impact of various progestins with or without transdermal testosterone on gonadotropin levels for non-invasive hormonal male contraception: A randomized clinical trial, Michael Zitzmann, Julia Rohayem, J. Raidt, Sabine Kliesch, Narender Kumar, and Régine Sitruk-Ware

Submissions from 2016

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Impact on hepatic estrogen-sensitive proteins by a 1-year contraceptive vaginal ring delivering Nestorone® and ethinyl estradiol, David F. Archer, M.A. Thomas, Jacqueline Conard, Ruth Merkatz, George W. Creasy, Kevin Roberts, Marlena Gehret Plagianos, Diana Blithe, and Régine Sitruk-Ware

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Delivering contraceptive vaginal rings to breastfeeding women, Population Council

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Introducing contraceptive methods in low-resource settings: New opportunities in Kenya, Population Council

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Introducing contraceptive methods in low-resource settings: New opportunities in Nigeria, Population Council

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Introducing contraceptive methods in low-resource settings: New opportunities in Senegal, Population Council

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Introducing the progesterone contraceptive vaginal ring in sub-Saharan Africa, Population Council

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Progesterone vaginal ring: Beneficial role in supporting breastfeeding, Population Council

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« Manifesto » de Paris : le temps est venu de disposer de nouvelles méthodes contraceptives masculines, David Serfaty, Régine Sitruk-Ware, Christina Wang, and Eberhard Nieschlag

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Hormonal contraception and thrombosis, Régine Sitruk-Ware

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Risk of pregnancy in breastfeeding mothers: Role of the progesterone vaginal ring on birth spacing, Régine Sitruk-Ware, Saumya RamaRao, Ruth Merkatz, and John Townsend

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A novel microbicide/contraceptive intravaginal ring protects macaque genital mucosa against SHIV-RT infection ex vivo, Guillermo Villegas, Giulia Calenda, Shweta Ugaonkar, Shimin Zhang, Larisa Kizima, Olga Mizenina, Agegnehu Gettie, James Blanchard, Michael Cooney, Melissa Robbiani, José Fernández-Romero, Thomas Zydowsky, and Natalia Teleshova

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Editorial: It is time for new male contraceptives!, Christina Wang, Régine Sitruk-Ware, and David Serfaty

Submissions from 2015

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A dose-finding, cross-over study to evaluate the effect of a Nestorone®/Estradiol transdermal gel delivery on ovulation suppression in normal ovulating women, Vivian Brache; Ruth Merkatz; Narender Kumar; Cristian Jesam Gaete; Heather Sussman; Elena Hoskin; Kevin Roberts; Mohcine Alami; DeShawn Taylor; Aidelis Jorge; Horacio B. Croxatto; Ellen Lorange; Daniel R. Mishell, Jr.; and Régine Sitruk-Ware

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An innovative financing model for the progesterone contraceptive vaginal ring through voucher programs, Ishita Chattopadhyay, John Townsend, and Saumya RamaRao

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Offering progesterone contraceptive vaginal rings for postpartum women through integrated family planning and immunization services, Ishita Chattopadhyay, John Townsend, and Saumya RamaRao

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Utilizing social marketing and social franchising models to expand access to the progesterone contraceptive vaginal ring, Ishita Chattopadhyay, John Townsend, and Saumya RamaRao

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Effects of a one year reusable contraceptive vaginal ring on vaginal microflora and the risk of vaginal infection: An open-label prospective evaluation, Yong-mei Huang, Ruth Merkatz, Sharon L. Hillier, Kevin Roberts, Diana Blithe, Régine Sitruk-Ware, and Mitchell Creinin

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Progesterone vaginal ring: Results of an acceptability study in Nigeria, Salisu Mohammed Ishaku, Afolabi Kayode, Godwin Unumeri, Ayodeji Oginni, Adekunle Adeyemi, Deepa Rajamani, Heather Clark, Naomi Rijo, and Saumya RamaRao

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Willingness to pay for contraceptive vaginal rings in Nigeria, Salisu Mohammed Ishaku, Ayodeji Oginni, Godwin Unumeri, and Deepa Rajamani

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Introduction of DMPA in public health facilities of Uttar Pradesh and Rajasthan: An evaluation, M.E. Khan, Anvita Dixit, Jaleel Ahmad, and G. Pillai

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Willingness to pay for contraceptive vaginal rings in Kenya, Wilson Liambila, Deepa Rajamani, Francis Obare, Saumya RamaRao, Harriet Birungi, and Heather Clark

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Delivering contraceptive vaginal rings: Review of postpartum service packages in Kenya, Wilson Liambila, Saumya RamaRao, and Heather Clark

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Delivering contraceptive vaginal rings—Task shifting and task sharing in the delivery of family planning services: Experiences from Kenya, Wilson Liambila, Saumya RamaRao, and Heather Clark

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Combination delivery of Adjudin and Doxorubicin via integrating drug conjugation and nanocarrier approaches for the treatment of drug-resistant cancer cells, Xu Li, Cuixia Gao, Yupei Wu, C. Yan Cheng, Weiliang Xia, and Zhiping Zhang

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L’anneau vaginal à progestérone: Résultats de l’étude d’acceptabilité au Sénégal, Babacar Mane, Papa Chimere Diaw, Nafissatou Diop, Fatou Mbow, Heather Clark, Saumya RamaRao, and Deepa Rajamani

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Delivering contraceptive vaginal rings—Task sharing in the delivery of family planning programs: Experiences from Senegal, Babacar Mane, Nafissatou Diop, and Saumya RamaRao

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Willingness to pay for contraceptive vaginal rings in Senegal, Babacar Mane, Fatou Mbow, Deepa Rajamani, Nafissatou Diop, and Saumya RamaRao

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L’offre des anneux vaginaux contraceptifs— La planification familiale postpartum: experience du Sénégal, Fatou Mbow, Babacar Mane, and Saumya RamaRao

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Progesterone vaginal ring: Results of an acceptability study in Kenya, Francis Obare, Wilson Liambila, Chi-Chi Undie, Harriet Birungi, Shiphrah Kuria, Heather Clark, Deepa Rajamani, and Saumya RamaRao

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Anneau vaginal à la progesterone: Appel a l'action pour combler les ecarts importants dans la planification familiale postnatal, Population Council

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Anneau vaginal à progestérone: aussi sûr pour maman que pour bébé, Population Council

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Anneau vaginal à progestérone: évite les grossesses, Population Council

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Delivering contraceptive vaginal rings, Population Council

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Distribution d'anneaux vaginaux contraceptifs, Population Council

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Expanding access to long-acting reversible contraceptives, Population Council