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Submissions from 2019

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New subtype B containing HIV-1 circulating recombinant of sub-Saharan Africa origin in Nigerian men who have sex with men, Erik Billings, Gustavo H. Kijak, Eric Sanders-Buell, Nicaise Ndembi, Anne Marie O'Sullivan, Sylvia Adebajo, Afoke Kokogho, Mark Milazzo, Kara Lombardi, Stefan Baral, Rebecca G. Nowak, Habib O. Ramadhani, Robert Gramzinski, Merlin L. Robb, Nelson L. Michael, Manhattan E. Charurat, Julie Ake, Trevor A. Crowell, Sodsai Tovanabutra, MHRP Viral Sequencing Core, and TRUST/RV368 Study Group

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Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques, Giulia Calenda, Ines Frank, Geraldine Arrode-Bruses, Amarendra Pegu, Keyun Wang, James Arthos, Claudia Cicala, Kenneth A. Rogers, Lisa Shirreff, Brooke Grasperge, James L. Blanchard, Stephanie Maldonado, Kevin Roberts, Agegnehu Gettie, Francois Villinger, Anthony S. Fauci, John R. Mascola, and Elena Martinelli

Submissions from 2018

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Integrin α_4β_7 blockade preferentially impacts CCR6^+ lymphocyte subsets in blood and mucosal tissues of naive rhesus macaques, Giulia Calenda, Rassamon Keawvichit, Geraldine Arrode-Bruses, Kovit Pattanapanyasat, Ines Frank, Siddappa Byrareddy, James Arthos, Claudia Cicala, Brooke Grasperge, James L. Blanchard, Agegnehu Gettie, Keith A. Reimann, Aftab A. Ansari, and Elena Martinelli

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Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo, Nina Derby, Manjari Lal, Meropi Aravantinou, Larisa Kizima, Patrick Barnable, Aixa Rodriguez, Manshun Lai, Asa Wesenberg, Shweta Ugaonkar, Keith Levendosky, Olga Mizenina, Kyle Kleinbeck, Jeffrey D. Lifson, M. Melissa Peet, Zachary Lloyd, Michael Benson, Walid Heneine, Barry R. O'Keefe, Melissa Robbiani, Elena Martinelli, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Natalia Teleshova, José Fernández-Romero, and Thomas Zydowsky

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Development of a vaginal fast-dissolving insert combining griffithsin and carrageenan for potential use against sexually transmitted infections, Manjari Lal, Manshun Lai, Shweta Ugaonkar, Asa Wesenberg, Larisa Kizima, Aixa Rodriguez, Keith Levendosky, Olga Mizenina, José Fernández-Romero, and Thomas Zydowsky

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Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7, Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa Byrareddy, Philip J. Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D. Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A. Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S. Fauci, and James Arthos

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MAdCAM costimulation through Integrin-α_4β_7 promotes HIV replication, Fatima Nawaz, Livia R. Goes, Jocelyn C. Ray, Ronke Olowojesiku, Alia Sajani, Aftab A. Ansari, Ian Perrone, Joseph Hiatt, Donald Van Ryk, Danlan Wei, Mia Waliszewski, Marcelo A. Soares, Katija Jelicic, Mark Connors, Stephen A. Migueles, Elena Martinelli, Francois Villinger, Claudia Cicala, Anthony S. Fauci, and James Arthos

Submissions from 2017

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Experimental oral herpes simplex virus-1 (HSV-1) co-infection in simian immunodeficiency virus (SIV)-infected rhesus macaques, Meropi Aravantinou, Olga Mizenina, Giulia Calenda, Jessica Kenney, Ines Frank, Jeffrey D. Lifson, Moriah Szpara, Lichen Jing, David M. Koelle, Natalia Teleshova, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Elena Martinelli, and Nina Derby

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MZC gel inhibits SHIV-RT and HSV-2 in macaque vaginal mucosa and SHIV-RT in rectal mucosa, Giulia Calenda, Guillermo Villegas, Patrick Barnable, Claudia Litterst, Keith Levendosky, Agegnehu Gettie, Michael Cooney, James Blanchard, José Fernández-Romero, Thomas Zydowsky, and Natalia Teleshova

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Pixuna virus modifies host cell cytoskeleton to secure infection, Pedro Ignacio Gil, Guillermo Albrieu-Llinás, Estela Cecilia Mlewski, Marina Monetti, Laura Fozzatti, Cecilia Cuffini, José Fernández-Romero, Patricia Kunda, and Maria Gabriela Paglini

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MIV-150 and zinc acetate combination provides potent and broad activity against HIV-1, Olga Mizenina, Mayla Hsu, Ninochka Jean-Pierre, Meropi Aravantinou, Keith Levendosky, Maria Gabriela Paglini, Thomas Zydowsky, Melissa Robbiani, and José Fernández-Romero

Submissions from 2016

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PolyICLC exerts pro- and anti-HIV effects on the DC-T cell milieu in vitro and in vivo, Meropi Aravantinou, Ines Frank, Magnus Hallor, Rachel Singer, Hugo Tharinger, Jessica Kenney, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Andres M. Salazar, Michael Piatak Jr., Jeffrey D. Lifson, Melissa Robbiani, and Nina Derby

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A small molecule, which competes with MAdCAM-1, activates integrin α4β7 and fails to prevent mucosal transmission of SHIV-SF162P3, Geraldine Arrode-Bruses, Diana J. Goode, Kyle Kleinbeck, Jolanta Wilk, Ines Frank, Siddappa Byrareddy, James Arthos, Brooke Grasperge, James Blanchard, Thomas Zydowsky, Agegnehu Gettie, and Elena Martinelli

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Rectal HSV-2 infection may increase rectal SIV acquisition even in the context of SIVΔnef vaccination, Natalia Guerra-Perez, Meropi Aravantinou, Filippo Veglia, Diana J. Goode, Rosaline Truong, Nina Derby, James Blanchard, Brooke Grasperge, Agegnehu Gettie, Melissa Robbiani, and Elena Martinelli

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In vitro inhibition of human papillomavirus following use of a carrageenan-containing vaginal gel, Akiva P. Novetsky, Marla J. Keller, Ana Gradissimo, Zigui Chen, Stephanie L. Morgan, Xiaonan Xue, Howard D. Strickler, José Fernández-Romero, Robert Burk, and Mark H. Einstein

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In vitro exposure to PC-1005 and cervicovaginal lavages from women vaginally administered PC-1005 inhibit HIV-1 and HSV-2 infection in human cervical mucosa, Guillermo Villegas, Giulia Calenda, Shimin Zhang, Olga Mizenina, Kyle Kleinbeck, Michael Cooney, Craig Hoesley, George W. Creasy, Barbara Friedland, José Fernández-Romero, Thomas Zydowsky, and Natalia Teleshova