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As noted in this brief, the female condom (FC) is the only female-initiated prevention product that provides simultaneous protection against pregnancy and sexually transmitted infections, including HIV. Although available for more than a decade, the FC remains limited in supply, not readily available, and underutilized. Obstacles to widespread availability and use are often generalized (e.g., high costs, resistance of partners, or unavailability). With the upcoming second generation of FCs—and ultimately microbicides—being added to female-initiated prevention methods, the need to overcome these impediments with concrete solutions is critical. Government and donor commitment to long-term, sustained supply and program support is essential. The Population Council will generate evidence through innovative program experimentation and by mapping the FC landscape in Kenya. Acceptability of the FC to users has been established through research in many countries, but no effort has been made to compare different programmatic delivery mechanisms and service delivery models. The Female-Initiated Prevention Methods project explores the appropriateness, feasibility, and effectiveness of three different means of delivering FC services in Kenya. Findings will inform a more acceptable delivery of FC to Kenyan women.